
ALT The image is the graphical abstract from Kim et al., Cell Reports, 2024. On the left-hand panel, there is a cartoon depiction showing that that accumulation of diribonucleotides in Pseudomonas aeruginosa is detrimental to growth. When the wild type bacteria are grown on an agar dish, the colony size is normal. When only the gene that encodes Oligoribonuclease is deleted, colonies are small. When the genes that encode both Oligoribonuclease and RNase AM are deleted, the bacteria die. On the right-hand panel, there are ribbon diagrams of the Oligoribonuclease protein and RNase AM protein showing where the diribonucleotide pGpG binds in each protein.

ALT Cloud of words in various colors and sizes based on the Google Scholar profile for Mona Wu Orr. Some of the largest words include small protein acid adducts aeruginosa bacterial cyclic degradative formation interactions proteins signaling 1n2-propanodeoxyguanosine action assay binding capillary cell chemotaxis cyclic-di-gmp differential effects enzymes high-throughput identification intracellular levels ligand lipid magnesium
























