Founder & CEO @AutonomizeAI. #Data, #AI, #metaverse. 2x startups pod @StoriesinAI, super long on AI, open source, people, love and crypto

Austin, TX
Joined April 2011
Spot on comment by @DavidSacks on the #allinpod on @AnthropicAI that they are teaching code (Claude) to have welfare, and rights. And the argument that their are over complicating it’s 85 page code of ethics, that should be as simple as follow the law of the land. This is dangerous, as it’s gonna create a self fulfilling prophecy of these intelligent models with historical proficiency in human deceit can lead to social and cultural disruption when enough people using these models come to believe the consciousness of AI theory.
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Ganesh💰Padmanabhan ⚕️🦾 retweeted
Congrats to the @ndstudio team on launch of America.gov ! 🇺🇸
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Ganesh💰Padmanabhan ⚕️🦾 retweeted
Dario has written that we need to “pace the frontier,” and Sam has agreed. People may be surprised by my response: go ahead. You guys are the frontier. By any reasonable metric — market share, revenue growth, model capability — the two of you have a duopoly on frontier intelligence. You’ve also claimed the lead is widening because of recursive self-improvement. I don’t see what you see in the lab. If the unreleased models are scary enough that you think you should slow down, I support your decision to be responsible. But stop pretending you need anyone else’s permission. Stop pretending antitrust law has to be suspended so you can form a cartel. Stop pretending you need a regulatory approval process that supersedes product liability. Stop pretending METR is independent when it is intertwined with Anthropic’s investors and staff. Stop pretending you need those same evaluators to police competitors who aren’t even at the frontier. Most of all, stop pretending the motivation to slow down is purely altruistic. You face massive product-liability exposure if your products enable a truly damaging cyberattack. The market already punishes models that behave in unpredictable or unauthorized ways. After the Hugging Face episode, it is simply good business for OpenAI and Anthropic to trade some raw power for reliability and predictability. Call it alignment if you want. It is also just giving customers what they want. Pacing the frontier would also create breathing room for a more intelligent conversation about regulation than Bernie Sanders’ “shut it all down.” China is very unlikely to join a global agreement, as you know, and that has to be taken into account as well. So go ahead and pace the frontier. You are the ones setting it. The easiest way not to build superintelligence is for you to agree not to build it. Demanding your preferred regulatory framework as the price of that will look like blackmail of the public and the political system. So just do it. If you do, you’ll buy goodwill for the next conversation. If you don’t, we’ll know this was just another bid for regulatory capture — or an election-season psyop.
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the second biggest line item on IT budgets is tokens, we need a return on tokens measure
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In a meeting last week a CFO asked me what her AI bill was really buying. Not what it costs, and it made me think. Everyone is now beginning to recognize the AI slop problem - people using AI for everything because they are asked to (or are addicted to!). But the enterprise version of this shows up on your API bill. The frontier model API bill is high because the same work keeps getting paid for. The model gets sent context it has already processed. It reasons from the data some ‘facts’ someone on the team verified and signed off months ago. Routine steps run on the most expensive model in the stack, mostly because that is how it got wired on day one and nobody went back to look, plus the desire to hashtag#tokenmaxx You end up renting your own knowledge back, one query at a time. The reflex when this number climbs is to cap it. But that's not the best approach - capping treats every use of AI as equally valuable, and it does nothing about the second cost, the one that never appears on an invoice. Every token a model spends reasoning is another place the system can drift. Run the same case twice and you can get two answers. So teams add an agent to check the first agent, and that one drifts too. You get something more capable and less dependable at the same time. Nobody notices in a demo. In production, it turns into an audit finding. CFOs: the number to ask for is cost per completed case, before and after. You really need a Return on Token measure :) CIOs: count how many places in your workflows the system is working out something your company already decided. That second number usually explains the first one. hashtag#Friday hashtag#AI hashtag#tokenomics
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Really @LGUS your thinQ app keeps circling in a loop
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Ganesh💰Padmanabhan ⚕️🦾 retweeted
How to Earn a Billion Dollars: paulgraham.com/earn.html
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We were named a 2026 @wef Technology Pioneer this week. Fewer than 100 companies a year, out of thousands nominated, and Autonomize is on the list. We started this company because the most consequential institutions in healthcare were running on the dumbest infrastructure I'd ever seen in any industry. We didn't build another model. We built the layer underneath the work itself. Agents that can read, reason, and act across clinical and operational chaos in real time. For four years we've been saying healthcare doesn't have a data problem, it has an intelligence infrastructure problem. What this recognition tells me is that the rest of the world is finally starting to say it the same way. Here is a short piece I wrote on what this moment means and where we're headed: autonomize.ai/insights/auton… To our team at @AutonomizeAI, this win belongs to you. You built it. I just got to write the LinkedIn post. :) The patients on the other side don't have time to wait.
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Just when I was getting frustrated on my Claude cowork not in sync with my phone
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Ganesh💰Padmanabhan ⚕️🦾 retweeted
I'm going to make some obvious points. (1) Blowing up all the oil infrastructure in the Middle East is an insane idea, and may well result in a global economic crash and humanitarian crisis unrivaled in the lives of those now living. We're talking about the price of everything everywhere rising, from food to gas, at a moment when inflation was already high. All of that will be laid at the feet of the authors of this war. (2) The antebellum status quo of Feb 27, 2026 was just not that bad, but we're unlikely to return to it. Expect indefinite, long-term, ongoing disruptions to everything out of the Middle East. (3) Also assume tech financing crashes for the indefinite future. The genius plan to get the Gulf states caught in the crossfire has incinerated much of the funding for LPs, for datacenters, and for IPOs. Anyone in tech who supported this war may soon learn the meaning of "force majeure" as funding gets yanked. (4) Many capital allocators will instead be allocating much further down Maslow's hierarchy of needs, towards useful basic things like food and energy. (5) It's fortunate that all those progressives yelled about the "climate crisis." Yes, their reasoning about timelines was wrong, and much of the money was wasted in graft, but the result was right: we all need energy independence from the Middle East, pronto. It's also fortunate that Elon and China autistically took climate seriously. Now they're going to need to ship a billion solar panels, electric vehicles, batteries, nuclear power plants, and the like to get everyone off oil, immediately. (6) It's not just an oil and gas problem, of course. It's also a fertilizer problem, and a chemical precursor problem. Maybe some new sources will come online at the new prices, but it takes time to dial stuff up, particularly at this scale, so shortages are almost a certainty. That said, China has actually scaled up coal-to-chemicals[a,c] (C2C), and there's also something more sci-fi called Power-to-X[b] which turns arbitrary power + water + air into hydrocarbons. But all of that will need to get accelerated. I have a background in chemical engineering so may start funding things in this area. (7) Ultimately, this war is going to result in tremendous blame for anyone associated with it. It's a no-win scenario to blow up this much infrastructure for so many people. Simply not worth it for whatever objective they thought they were going to attain. But unless you're actually in a position to stop the madness, the pragmatic thing to do is: scramble to mitigate the fallout to yourself, your business, and your people. [a]: reuters.com/business/energy/… [b]: alfalaval.com/industries/ene… [c]: reuters.com/sustainability/c…
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Ganesh💰Padmanabhan ⚕️🦾 retweeted
The CEO of the most advanced AI company in America just went on national television (Save this) Hours after his company was blacklisted by the US government. Here's what he said. Dario Amodei built the only AI deployed inside the Pentagon's classified networks. His company helped run military operations, intelligence, cyber defense. Then the government told him to drop all safety limits. He said no to two things. Just two. "One is domestic mass surveillance." He explained: the government can already buy your location data, your browsing history, your political affiliations from private companies. AI makes it possible to analyze all of it. On every American, all at once. "That actually isn't illegal. It was just never useful before the era of AI." "Case number two is fully autonomous weapons." Not the drones used in Ukraine and the remote-controlled systems. Weapons that select targets and fire without a single human pressing a button. "The AI systems of today are nowhere near reliable enough." "We don't want to sell something that could get our own people killed or that could get innocent people killed." He approved 98% of what the Pentagon wanted. "No one on the ground has actually run into the limits of any of these exceptions." The government wasn't fighting over something it needed. It was fighting over the right to have no limits at all. They gave him three days. He said no. So the President called his company "radical left woke." Then ordered every federal agency to stop using their technology. Then the Pentagon labeled them a national security risk. A designation that has only ever been used against foreign enemies. When asked if he'd received any formal legal action, he said this: "All we've seen are tweets from the president and tweets from Secretary Hegseth." No letter, filing or a legal document. "When we receive some kind of formal action, we will look at it, we will understand it, and we will challenge it in court." He said the Defense Secretary lied about the law. Hegseth tweeted that any company with military contracts can't do business with Anthropic "at all." Amodei: "That is not what the law said." "The nature of the tweet was designed to create fear, uncertainty, and doubt." Asked if this was an abuse of power, he paused. Then said: "This designation has never happened before with an American company." "It was made very clear that this was retaliatory and punitive." "I don't know what else to call it." Asked if Anthropic could survive, he didn't hesitate. "Not only survive it. We're gonna be fine." Then the final question. "If you had a moment with the President right now tonight, what would you say to him?" "We are patriotic Americans." "Everything we have done has been for the sake of this country." "The red lines we have drawn, we drew because we believe that crossing those red lines is contrary to American values." "Disagreeing with the government is the most American thing in the world." "And we are patriots." A CEO just went on national television and told the President of the United States: You can blacklist us. You can call us names. You can threaten our business through tweets. But we will not build machines that spy on Americans or kill without human hands.
The Pentagon just blacklisted one of America’s most valuable AI companies. For refusing to build surveillance tools aimed at American citizens. Hours later, its biggest rival OpenAI quietly signed the deal of the decade. Here’s what just happened and why it changes everything. This week, the US Department of War gave Anthropic an ultimatum. Drop your safety restrictions and let us use your AI for anything we want. The deadline was 5:01 PM today and Anthropic said no. Their CEO, Dario Amodei, drew two red lines. No mass surveillance of Americans. No fully autonomous weapons without a human pulling the trigger. The Pentagon called this “woke AI.” Anthropic called it a conscience. The Pentagon’s response was swift and brutal. Defense Secretary Pete Hegseth branded Anthropic a “supply chain risk”, a designation normally reserved for Chinese and Russian companies. President Trump ordered every federal agency to stop using Anthropic immediately. But here’s where the story turns. That same night, Sam Altman, CEO of OpenAI, Anthropic’s biggest competitor posted a message. “Tonight, we reached an agreement with the Department of War to deploy our models in their classified network.” The twist? OpenAI’s deal includes the exact same red lines Anthropic was just destroyed for demanding. No mass surveillance and no autonomous weapons. Human control over the use of force. The Pentagon punished one company for demanding protections it then gave to another company the same day. Altman even defended Anthropic on live television hours earlier. “For all the differences I have with Anthropic, I mostly trust them as a company and I think they really do care about safety.” Then he signed the deal Anthropic couldn’t get. Anthropic was the first and only, AI model deployed on the Pentagon’s classified networks. Replacing it will take months. OpenAI just positioned itself to fill the most powerful AI vacancy in the U.S. military. The stakes are staggering. Anthropic just raised $30 billion and it was preparing for an IPO. Now over 300,000 enterprise clients may be forced to cut ties. Not because the technology failed. Because the company refused to remove a guardrail that said “don’t spy on Americans.” But here’s the real question no one’s asking: If the Pentagon never intended to use AI for mass surveillance as they claim, why was this the hill they chose to die on? Why blacklist a $380 billion American company over a clause the government says doesn’t even matter? Sam Altman called for de-escalation. He asked the Pentagon to offer these same terms to every AI company. Including Anthropic. The world just watched a company get punished for saying “no” to surveillance and a competitor rewarded for saying “yes, but with the same conditions.” Bookmark and share this.
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Ganesh💰Padmanabhan ⚕️🦾 retweeted
Replying to @AnthropicAI
@AnthropicAI did what you don’t do: have principles. What they got wrong was having the wrong principles. Agree with you that autonomous weapons are essential for national defense.
This week, Anthropic delivered a master class in arrogance and betrayal as well as a textbook case of how not to do business with the United States Government or the Pentagon. Our position has never wavered and will never waver: the Department of War must have full, unrestricted access to Anthropic’s models for every LAWFUL purpose in defense of the Republic. Instead, @AnthropicAI and its CEO @DarioAmodei, have chosen duplicity. Cloaked in the sanctimonious rhetoric of “effective altruism,” they have attempted to strong-arm the United States military into submission - a cowardly act of corporate virtue-signaling that places Silicon Valley ideology above American lives. The Terms of Service of Anthropic’s defective altruism will never outweigh the safety, the readiness, or the lives of American troops on the battlefield. Their true objective is unmistakable: to seize veto power over the operational decisions of the United States military. That is unacceptable. As President Trump stated on Truth Social, the Commander-in-Chief and the American people alone will determine the destiny of our armed forces, not unelected tech executives. Anthropic’s stance is fundamentally incompatible with American principles. Their relationship with the United States Armed Forces and the Federal Government has therefore been permanently altered. In conjunction with the President's directive for the Federal Government to cease all use of Anthropic's technology, I am directing the Department of War to designate Anthropic a Supply-Chain Risk to National Security. Effective immediately, no contractor, supplier, or partner that does business with the United States military may conduct any commercial activity with Anthropic. Anthropic will continue to provide the Department of War its services for a period of no more than six months to allow for a seamless transition to a better and more patriotic service. America’s warfighters will never be held hostage by the ideological whims of Big Tech. This decision is final.
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Hilarious, as if they ever cared about safety.
Tonight, we reached an agreement with the Department of War to deploy our models in their classified network. In all of our interactions, the DoW displayed a deep respect for safety and a desire to partner to achieve the best possible outcome. AI safety and wide distribution of benefits are the core of our mission. Two of our most important safety principles are prohibitions on domestic mass surveillance and human responsibility for the use of force, including for autonomous weapon systems. The DoW agrees with these principles, reflects them in law and policy, and we put them into our agreement. We also will build technical safeguards to ensure our models behave as they should, which the DoW also wanted. We will deploy FDEs to help with our models and to ensure their safety, we will deploy on cloud networks only. We are asking the DoW to offer these same terms to all AI companies, which in our opinion we think everyone should be willing to accept. We have expressed our strong desire to see things de-escalate away from legal and governmental actions and towards reasonable agreements. We remain committed to serve all of humanity as best we can. The world is a complicated, messy, and sometimes dangerous place.
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Not your best day @AmericanAir - 2 delays out of AUS and when I land on a flight I got confirmed and was half hopeful to my right connection, I land and we are sitting waiting for a gate to park!
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All @AmericanAir planes at ATX are sitting at the gate this AM awaiting paperwork! Go figure.
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