Neurodegeneration and stroke research lab at QBI. We specialise in epigenetics and mitochondria in C. elegans.

University of Queensland, Brisbane, Aust…
Joined June 2016
Out today! We find that an epigenetic modification (6mA) to the mitochondrial genome (mtDNA) influences lifespan and the heritability of mtDNA mutations to the next generation. It implies that epigenetics determines genetic composition in future offspring. cell.com/cell-metabolism/ful…
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Abstract submission and registration closes soon for the Cell Biology of the Nervous System in Crete. Hope to see you there!
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Congratulations to Anne Hahn from our lab who has won the best PhD student publication in 2024 at our institute @QldBrainInst 🥳🥳🥳 2nd year in a row we have won this award! Well done, Anne! Her amazing paper is pinned above.
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This year’s medicine laureates Victor Ambros and Gary Ruvkun studied a relatively unassuming 1 mm long roundworm, C. elegans. Despite its small size, C. elegans possesses many specialised cell types such as nerve and muscle cells also found in larger, more complex animals, making it a useful model for investigating how tissues develop and mature in multicellular organisms. Read how the 2024 medicine laureates’ investigations into C. elegans revealed an entirely new dimension to gene regulation: bit.ly/4dlPE6f #NobelPrize
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BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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Anne from tha lab, has a podcast episode!
While many products promise to reverse ageing without scientific backing, the real secret may lie in epigenetics! Dr Anne Hahn discusses her research into a mechanism in DNA that regulates the inheritance of disease-causing mutations. Listen: bit.ly/3TKI8L5 @ZurynLab
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Do you know a grad student who has completed an outstanding PhD research project in #genetics & #genomics of #Celegans? Nominate them for the Sydney Brenner Dissertation Thesis Award by Sept 30—the recipient will present their research at #Worm25: bit.ly/3MGtVLv 🪱🧬
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Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳 Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!  biorxiv.org/content/10.1101/…
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Very cool that our lab will be part of this new NHMRC centre of research excellence led by Prof Jürgen Götz @AustraliaGoetz to investigate the mitochondrial contribution to Alzheimer's disease and treatments 👏 @QldBrainInst
Exciting news! #UQ researchers at have secured two $3 million grants from the National Health and Medical Research Council (NHMRC) to fast-track Alzheimer's disease treatments and enhance gynaecological cancer care. Read: qbi.uq.edu.au/article/2024/0…
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We find that mtDNA 6mA is wdiely conserved across animals and plants, including human cells implying an ancient mechanism of regulation. This work was driven by Dr Anne Hahn in the lab and is out in @Cell_Metabolism.
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QBI researchers have discovered a DNA mechanism that controls how disease-causing mutations are inherited. Dr. Anne Hahn and A/Professor Steven Zuryn believe this could lead to therapies that prevent heritable and age-related diseases. Read: bit.ly/3Mhm5Yu @ZurynLab
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We built a simple App to help identify genetic markers for C. elegans crosses. Great for the lab and for teaching genetics! academic.oup.com/g3journal/a…
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Congratulations to Assoc Prof Steven Zuryn @ZurynLab , the winner of the @GeneticsAus Ross Crozier Medal for outstanding contributions to the field of genetics research by mid-career Australasian scientist. #GSA2024
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Wrapping up the middle session with Anne Hahn from @ZurynLab 🪱 🧬 @QldBrainInst #BCDBM @anzsc
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Congratulations to Professor Barry Dickson who was elected as a Fellow of the Royal Society. The neurobiologist has been involved with science for 30 years and is known for his studies of fruit fly mating behaviours. 🔗bit.ly/3QOiW4W
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The brain makes us human, yet we are only just starting to develop a detailed understanding of its function. What lies ahead in the world of neuroscience? Find out in our latest edition of The Brain Magazine. Read: 🔗 bit.ly/3RDmqZ3 #UQ #QBI #brain #science #magazine
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Zuryn Lab retweeted
🎉On this day, 25 years ago, the first complete animal genome sequenced was published in Science. 25 years later, this nematode is still a pioneer in many scientific fields. Long life to #Celegans research!
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What an incredible way to celebrate 20 years at the Queensland Brain Institute! 🎉 From our humble beginnings in 2003 to now standing tall as a global leader, this incredible journey wouldn't have been possible without our amazing community. 💜 #UQ #QBI #20Years Ahead
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