
@YasarHammori
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Asst Prof| Medical Oncologist| Medical Educator| @annualsdui SDUI 2017-2020|๐ธ๐ฉ๐ฎ๐ช
Dublin , Ireland
Joined April 2018
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Some call us Arabs, some call us Africans, and some call us Afro-arab... Being Sudanese is not about ethnicity, it's all about the values that we embrace, love we share, ethics and values embroided to our souls.
#SudanProtests
#SudanUprising
#ุงูุณูุฏุงู โ at Khartoum, Sudan
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Exploring the immunological effects of antibodyโdrug conjugates
nature.com/articles/s41571-0โฆ
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Are you heading to #ESMO26 in Madrid? Donโt forget to attend the ESMO-MCBS special session on Friday afternoon! @oncology_bg will talk on how to read a clinical trial! cslide.ctimeetingtech.com/esโฆ
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๐Excited to share our publication evaluating TP53 alterations with a closer look at TP53 Y220C alteration in metastatic breast cancer @JCOOA_ASCO
ascopubs.org/doi/10.1200/OA-โฆ
@YaleBreast @YaleCancer @FoundationATCG @maryam_lustberg @AdrianaKahnMD
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Advances in Systemic Treatment of Breast Cancer | New England Journal of Medicine nejm.org/doi/full/10.1056/NEโฆ Excellent review @NEJM @OncoAlert
Presented at #IGCS2026: Our structured needs assessment on Gynecologic Oncology capacity in Sudan post-armed conflict (14 facilities across 10 states):
โข Brachytherapy unavailable across all surveyed sites
โข Radiation wait times >5โ8 weeks where referrals exist
โข Screening absent in 79% of centers
Internally displaced persons comprise up to 50% of the patient volume at receiving peripheral centers, alongside severe deficits in surgical oncology workforce and basic palliative care (oral morphine).
Targeted global oncology support is urgent.
โ๐ shorturl.at/RE7To
@IGCSociety
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This randomized trial examined whether adding a multicancer early-detection blood test to usual care reduces late-stage cancer diagnoses in adults 50 to 77 years of age. Research findings from the NHS-Galleri trial are summarized in a new Quick Take video. nej.md/4iZFheW
How should we govern AI in health professions education?
1/5 AI in health professions education is not just a technology question. It is a question of governance, ethics, academic integrity, equity and professional identity.
Our critical narrative review examines these challenges.
๐ shorturl.at/V450L
2/5 First: governance. Institutional responses may be fragmented, while educational applications of AI continue to evolve.
How can policies remain useful without becoming quickly outdated?
3/5 Second: ethics. AI raises difficult questions about autonomy, beneficence, non-maleficence and justiceโparticularly when systems are opaque or data-driven.
4/5 Third and fourth: generative AI challenges established ideas of authorship and academic integrity, while bias and unequal access raise concerns about equity and professional development.
5/5 Responsible AI in medical education needs more than a blanket โallowโ or โban.โ
Our review proposes a risk-based governance taxonomy. What should institutions prioritise first: transparency, assessment integrity, fairness or accountability?
#MedicalEducation #AIethics
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Use of Vaginal Estrogen in Breast and Gynecologic Cancer Survivors | JCO Oncology Practice ascopubs.org/doi/10.1200/OP-โฆ @OncoAlert @JCOOP_ASCO @MMAlHilli @ClevelandClinic in selected patients with refractory symptoms low dose vaginal estrogen could be effective !
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Pretty stunning review on advances in breast cancer treatment in this weekโs NEJM
So many new approvals since 2020 that they could only fit on a 2-page centerfold!!!
Looks like itโs the roaring 20s in breast cancer research!
#bcsm
โ๏ธShould AI in medical education be banned, permitted, or governed according to risk?
๐ฐOur new critical narrative review examines the ethical and regulatory challenges of AI in Health Professions Education.
๐452 records โ 34 included sources โ 4 major themes โ a proposed risk-based governance taxonomy.
๐กThe question may no longer be simply whether AI belongs in medical education, but how different AI applications should be governed according to their educational risk.
๐ J Adv Med Educ Prof. 2026;14(4):307โ319
DOI: 10.30476/jamp.2026.110257.2340
shorturl.at/xrag2
#AI #MedEd #MedicalEducation #AIgovernance
๐งฌ Can molecular profiling help us understand survival after liver-directed therapy in metastatic uveal melanoma?
Our abstract in ESMO Open explores the impact of tumour biology on outcomes following chemosaturation with percutaneous hepatic perfusion (CS-PHP).
In our cohort of 12 patients, exploratory molecular analysis found that:
๐น BAP1 loss/mutation was associated with shorter overall survival
๐น Monosomy 3 was also associated with less favourable outcomes
These findings suggest that molecular features may provide important prognostic information beyond clinical treatment outcomes and could potentially help refine patient selection and treatment strategies.
The study also reports an ORR of 66.7%, median hepatic PFS of 18.4 months and median OS of 28 months, with no treatment-related fatalities.
While these molecular findings require validation in larger prospective cohorts, they highlight the importance of integrating tumour biology with liver-directed treatment in metastatic uveal melanoma.
๐ Read our study in ESMO Open:
shorturl.at/Z6ald
Guidelines still disagree on how long to taper steroids after ICI-myocarditis.
ESC favours 17โ20 weeks to reduce recurrence, SITC/ASCO/NCCN favour 4โ6 weeks to limit infection, metabolic and CV toxicity.
Convert IV to oral prednisone ~1 mg/kg (max 80 mg) once troponin has fallen >50% & the patient is electrically and haemodynamically stable.
Then individualise the taper to troponin normalisationโnot a fixed calendar.
#CardioOnc #CardioOncology #ICI #Myocarditis #irAE #Immunotherapy
rdcu.be/4ExuHmNDiGna
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#WCLC 2026 "One slide says it all"! from our presentation on impact of KRAS G12C on patient outcomes in EMPOWER lung 01 phase 3 trial of 1st line cemiplimab vs platinum chemotherapy. Explanation: G12C is highly associated with smoking, most neoantigenic, favorable to ICI.
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Exam-Important Chest X-Rays: Key Findings for Medical Students.
#Radiology #ChestXRay #MedEd #Medicine #Doctor
Landmark, practice-changing data at @IASLC #WCLC26! ๐จ The Phase 3 MAVERIC trial compared PCI vs MRI surveillance in SCLC (~68% LS, 32% ES).
โก๏ธMRI surveillance improved cognitive failure-free survival (CFFS) with NO detriment to OS, avoiding the significant G3+ toxicity of the PCI arm. While PCI decreased brain mets, PFS was unchanged.
In the MRI era, PCI has no clear role in either LS- or ES-SCLC management.
RIP PCI! ๐ชฆ๐
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IASLC expert panel proposes an updated pulmonary carcinoid/NET classification ( Expected to be included into the forthcoming WHO thoracic blue book)
1. Keep โcarcinoidโ as the main diagnostic term for thoracic clinicians, while moving toward the โNETโ nomenclature used in other organs
2. Add Ki-67 as a diagnostic criterion. 5% threshold is pulmonary specific
3. Formally recognize rare carcinoid/NET G3 tumors (higher proliferation, but molecularly closer to NETs than to high-grade NECs)
More on jto.org/article/S1556-0864%2โฆ
Slides below from Dr. Bellizziโs presentation: Whatโs New in Neuroendocrine Tumors (WHO 6th Edition, 2026)
youtube.com/live/o8IqIDiN_Jwโฆ #pathology #pathX
Delighted to share our new review, open access in Discover Medicine: "Current evidence on the diagnosis and management of immune checkpoint inhibitor associated myocarditis."
A practical map through a rare but frequently fatal irAE. Thread
ICI-myocarditis hits ~1% of patients on checkpoint inhibitors, more with combination regimens. Mortality was reported as high as 50% in early cohorts โ recent data (2021โ22) puts it closer to 26%, likely from earlier detection + faster steroids ๐งต.
Diagnosis: we walk through the IC-OS 2021 criteria and the 2024 ACC Consensus Pathway โ troponin-anchored, cardiac MRI as the major imaging criterion, endomyocardial biopsy as the diagnostic fail-safe when CMR is non-diagnostic or the patient is unstable.
4/ Risk stratification: a validated 8-point score predicts 30-day MACE from 4% (score 0) to >80% (score โฅ4) using thymoma status, symptoms, QRS voltage, LVEF and troponin magnitude. Very-low-risk patients may avoid high-dose steroids entirely.
Up to 50% of patients fail first-line high-dose corticosteroids. We review the evidence โ almost all case-series level โ for second-line agents: MMF, tacrolimus, abatacept, ATG, infliximab, tocilizumab, ruxolitinib. No RCT data yet exists for any of them.
Full text (open access): doi.org/10.1007/s44337-026-0โฆ With Hatim Ibrahim, Diya M Sabu, Hebatalla Ismail, Fahad Farooq โ St. Vincent's UCD Cancer Centre.
#CardioOncology #Oncology #Cardiology #MedTwitter @UCDMedicine , @svuh @SpringerNature @Discovery_Med @Discover_Jrnls




































