Professor of Computational Biology for Individualised Infection Medicine

Hannover, Germany
Joined March 2015
Happy to share our latest review paper. "The role of DNA methylation in personalized medicine for immune-relate diseases " #PersonalizedMedicine #ImmuneDiseases #DNAmethylation sciencedirect.com/science/ar…. @MANOJKU05959576 @YangLi_Lab
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Are you a recent Ph.D. graduate eager to take the next step in your academic career? Our research group is looking for a dedicated postdoctoral scholar to work on cutting-edge projects in single-cell omics. rb.gy/xck8o
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Happy to share my latest research on disease prediction "Nasal DNA methylation at three CpG sites predicts childhood allergic disease". nature.com/articles/s41467-0…, published in @NatureComms . Great team work with @CancanQi @micompanynl @researchumcg @Helmholtz_CiiM @MHH_life
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A lot of good wishes for the future CiiM were just put into the foundation stone. The time capsule also contains some Polaroids from the day, a newspaper and information about the CiiM.
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If you're interested in how genetics affect our immune responses to pathogens, how this helps us understand #LymeDisease or how not to iron a shirt, come visit my reviewer's choice awarded poster at 3pm #ASHG2022 Poster No. 1235 Or drop me a DM anytime!
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New preprint, in which we investigate gene essentiality across Escherichia, Salmonella, Klebsiella and related genome-reduced endosymbionts -- we show that some genes rapidly change essentiality status over evolution, probably driven by genomic context biorxiv.org/content/10.1101/…
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Our paper is out @NatureComms, Single-cell transcriptomics analyses reveal reprogramming of myeloid cells and their progenitors in thyroid carcinoma patients. Great team work with Romana T. Netea-Maier, Katrin Rabold, Martijn Zoodsma and @YangLi_Lab. nature.com/articles/s41467-0…
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The response to anti-#tuberculosis BCG vaccine is variable. @VKoeken @YangLi_Lab &co show that the baseline plasma metabolome can partially predict trained immunity upon BCG #vaccination, identifying it as a potential source of heterogeneity #PLOSBiology plos.io/3LgHDDd
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Noch 20 Tage bis zum 14. TWINCORE Symposium! Dieses Jahr gemeinsam mit den 13. Internationalen VPM-Tagen am 15. und 16 September. Infos und Anmeldung unter twincore.de/veranstaltungen/…
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Yang Li retweeted
Very happy to share our current work "Cell-type eQTL deconvolution of bronchial epithelium through integration of single-cell and bulk RNA-seq" @ChengjianXu @MC_Nawijn @YangLi_Lab onlinelibrary.wiley.com/shar…
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Very readable article about unmet needs in IBD by @charlie_lees🎊 - I myself believe in the high necessity of precision medicine in IBD therapies and can only agree with Charlie: due to the high complexity we will need to break it down on a single cell level: @YangLi_Lab 🧬
Replying to @charlie_lees
Read Atomic IBD for a detailed exploration of the urgent unmet need in IBD I am interested in your comments. What would you add? Which to do you see as the easiest wins and the biggest challenges? charlielees.substack.com/p/t…
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Jetzt im vollen Gange: Der erste jährliche #Retreat des @BIOMEDAS_PhD Programms am #TWINCORE, Die Teilnehmenden u.a. von @Helmholtz_CiiM, @MHH_life. @TWINCOREtweets, @TIBHannover, @Helmholtz_HZI, @tuBraunschweig präsentieren ihre Forschungsprojekte. 💻🔬🧬translationsallianz.de/biome…
So proud of coordinating together with the team @MHH_life the D-SOLVE consortium funded by @HorizonEU that aim for personalized #HepatitisD treatment. ciim-hannover.de/en/d-solve/
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Welche genetischen Faktoren sind an den Immunmechanismen bei der Entstehung von Typ-1-#Diabetes beteiligt? Lest zur Studie von @YangLi_Lab, Direktorin @Helmholtz_CiiM, auch die Pressemitteilung vom Journal @eLife. #T1D elifesciences.org/for-the-pr…
How genetics influence immunity in patients with type 1 diabetes. elifesciences.org/articles/7…
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We are looking for candidates for a new department on #personalised #immunotherapy ciim-hannover.de/en/personal…. Interested in joining our growing team @Helmholtz_CiiM and help establishing a new field and institute? We are curious to get to know you!
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Very excited to share our article “The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses " frontiersin.org/article/10.3…. Great team work together with Mihai Netea, @YangLi_Lab,@YunusKuijpers, @Helmholtz_HZI, @Helmholtz_CiiM, @radboudumc_weet
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