@YHGanLab

We are led by @yunnhwen and are dedicated to Klebsiella pnuemoniae research. Tweets are by lab members and do not represent the opinions of our institute

 MD7, 8 Medical Drive, NUS
gyhlab.wixsite.com/gyhlab
Joined April 2020
  • Tweets403
  • Following111
  • Followers291
67Media
Our most recent story delves into the realm of small RNAs in hvKp🧬! Led by @KJwushuguy, he applied RIL-seq to unravel the Hfq-mediated RNA-RNA interaction network, and revealed the capsule gene loci as a major hub for sRNAs to regulate capsule physiology. academic-oup-com.libproxy1.n…
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📣 Postdoc position available in my group at Pitt to study how Klebsiella controls its cell surface and develop new projects. themikelab.com Read more and apply here by Jan 12: cfopitt.taleo.net/careersect… Reposts are appreciated! #klebclub #newPI
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Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention Holmes, Bachman & co. explore major pathogens causing bloodstream infections, their pathogenesis, opportunities for prevention, diagnosis & treatment options.
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🆕 Antimicrobial resistance poses an important global health challenge in the 21st century. A new in-depth global analysis suggests more than 39 million deaths from antibiotic-resistant infections could occur between now & 2050. Explore the data: buff.ly/3zlVE0U #AMR
Figure showing global attributable and associated AMR burden in the reference scenario, 2022–2050. Copyright: 2024 The Author(s). Published by Elsevier Ltd. CC By 4.0

ALT Figure showing global attributable and associated AMR burden in the reference scenario, 2022–2050. Copyright: 2024 The Author(s). Published by Elsevier Ltd. CC By 4.0

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Last week, AMR researchers worldwide gathered in SG for the #AMRsymposium2024. Over three days, numerous great and inspiring presentations covered every key aspect of AMR!
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Hurry! Earlybird registration closes on June 30 for our #AMR symposium held in Singapore in Sept! Groups of 5 or more entitled to an additional 20% discount (please email [email protected]). Fantastic line-up of speakers!
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#JobAlert Interested in a #Postdoc in microbial genetics ? DM for more details Join me in #Toulouse, a vibrant dynamic city ☀️ offering high quality of life & near 🏔️ &🏖️ Applications until end of month. ** Please RT ! ** @CbiToulouse #ASMicrobe @KlebClub #Klebsiella
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Congratulations to Dr Chang kai qing 🥳🥳 @changkc_
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We will soon have open positions for PhD/postdocs with computational and/or experimental training to work on topics related with social interactions from an eco-evo perspective. Early and spontaneous applications are encouraged @KlebClub #AMR
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Congratulations on your achievement! 🥳 @yihan_kaiserin
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We are holding an #AMR symposium in sunny Singapore with regional and international speakers. Hope you can join us! Registration and abstract details will be released soon and meanwhile check out the preliminary website for more details. snbc.sg/news-events-2/antimi…
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I'm happy to share our latest publication on⚔️ warfare between hypervirulent #klebsiella pnuemoniae and gut bacteria! Led by Tan Yi Han, we showed that the ST23 lineage employs colibactin to kill commensal species with the help of microcin E492 academic.oup.com/ismej/advan…

Hypervirulent Klebsiella pneumoniae employs genomic island encoded toxins against bacterial...

Abstract. The hypervirulent lineages of Klebsiella pneumoniae (HvKp) cause invasive infections such as Klebsiella-liver abscess. Invasive infection often o

academic.oup.com
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YHGanLab retweeted
Yuan@Yuanqiao10027 Mar 2024
#SGBUG online seminar is back on 21st March. Join us to hear the exciting work by Xiaohui Zhao (Zhejiang University). Scan the QR code to register! 😃
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Setting sail for a great year after CNY~ ⛴️⛴️
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We are hiring! If you have expertise in metagenomics, genome assembly, microbial isolation or high-throughput biology and want to do #AMR research, please do write to me with your CV
A*STAR Research@astar_research21 Feb 2024
Congratulations to Niranjan Nagarajan of @astar_gis, who was recently selected for the prestigious NRF Investigatorship! 🌟 @astar_research recently featured Nagarajan’s in-depth study on CPE, a class of antibiotic-resistant bacteria. Full story here ⬇️ bit.ly/46lBTkW

Hidden threats from benign colonisers

Genomic profiles of the human gut microbiome reveal the hidden impacts of asymptomatic, antibiotic-resistant bacterial infections, as well as potential solutions for their reversal.

research.a-star.edu.sg
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Increase of hypervirulent carbapenem-resistant Klebsiella pneumoniae in the EU/EEA ecdc.europa.eu/en/news-event…

Increase of hypervirulent carbapenem-resistant Klebsiella pneumoniae in the EU/EEA

Since the most recent ECDC rapid risk assessment in 2021, the number of EU/EEA countries reporting hypervirulent Klebsiella pneumoniae (hvKp) sequence type (ST) 23 has increased from four to ten and...

ecdc.europa.eu
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Our latest publication, led by @changkc_, examines the role of short-chain fatty acids in deterrence against Klebsiella pneumoniae and Enterobacteriaceae species. Longer SCFA alkyl chain lengths exert more potent inhibition! Read further: journals-asm-org.libproxy1.n…
YunnHwen Gan@yunnhwen3 Feb 2024
Congrats to @changkc on her publication based on her PhD! Short-chain fatty acids of various lengths differentially inhibit Klebsiella pneumoniae and Enterobacteriaceae species | mSphere (asm.org) @YHGanLab @NiranjanTW
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Registration is still open for the fifth annual Klebsiella Seminar Series! Join us for a great line up of speakers from all across the pathogenesis field. Abstracts will be accepted until February 11th and are welcome from all training levels! #KlebClub sites.google.com/view/klebcl…
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Here's our latest endeavour into #AI-driven identification of synergistic drug combinations (out of half a million possible ones!) with broad spectrum activity against #MDR bacteria Read more: onlinelibrary.wiley.com/doi/….
YunnHwen Gan@yunnhwen19 Jan 2024
A great group effort in identifying broad spectrum,new drug combinations against #MDR bacteria using #AI platform! onlinelibrary.wiley.com/doi/…. @thedeanh @YHGanLab @echow310 @OonTek1
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New papers out in @Nature on a new antibiotic class targeting the LPS transporter in carbapenem-resistant Acinetobacter baumannii nature.com/articles/s41586-0… nature.com/articles/s41586-0…
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