Associate Professor & CPRIT scholar @MDAndersonNews studying stress responses in tumor microenvironment and anti-tumor immunity.
Houston, TX
Joined September 2020
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Many congratulations to @LV_Xiangdong who has been awarded the CPRIT scholar award to set up his own lab at @UTHealthHouston! He is amazing!
BREAKING NEWS: #CPRIT approved $89 million in grants to advance the state’s fight against cancer, including CPRIT Scholar recruitment awards, evidence-based prevention programs and innovative companies developing new cancer drugs and treatments.
READ: ow.ly/m9Qg50Ub8qi
Xi Chen retweeted
Thank you @theNAMedicine @MDAndersonNews and all who contribute to our mission to #endcancer - patients and families, care teams, researchers and supporters worldwide. Honored to continue this important work together
Jennifer A. Wargo (@jenwargomd) of @MDAndersonNews was elected as a member of the National Academy of Medicine in 2023. Congratulations and welcome! #NAMclassof2023
Happy to share our latest work showing that an ancient ER-localized RNase IRE1 coordinates with p53 to silence taxane-induced dsRNA and protect immune-cold TNBC from pore-forming pyroptosis. @CellCellPress @MDAndersonNews cell.com/cell/abstract/S0092…
Xi Chen retweeted
Here are 10 things to know about our Dr. Jim Allison, who was recently elected to the 2024 National Inventors Hall of Fame. @JimAllisonPhD @InventorsHOF #EndCancer
#NIHF2024 Inductee @JimAllisonPhD has a deep appreciation for endeavors that enrich life. His love of music has led him to play in a blues band composed of @sitcancer members & immunologists or oncologists, called The Checkpoints. @MDAndersonNews bit.ly/44nkB72
Xi Chen retweeted
The Allison Institute will be hosting a Next Gen Colloquium in Houston ahead of SITC in November. Details in photo. Please sign up or contact me with any questions.
Xi Chen retweeted
Recruiting faculty to the Dept of Molecular and Cellular Biology at Baylor College of Medicine in Houston! Recruiting broadly in cancer and cell biology. Apply by Nov 1, 2023. @BCMhouston
nature.com/naturecareers/job…
bcm.edu/departments/molecula…
Wonderful session on #UPR and #ISR. Learned a lot from the amazing talks from @ACKoongMDPhD @Eric_Chevet @apoptosislab !
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Happy to share our latest work in collaboration with @HaoqiangY published in @ScienceMagazine today: Proteostasis network reprogramming is a key convergence point of multiple KRAS inhibitor resistance mechanisms.
science.org/doi/10.1126/scie…
Kudos to @LV_Xiangdong @XuanLu11447800 and all authors for the fantastic teamwork. Thanks @NCICancerBio for supporting this work.
Happy to share our latest work with Stanley Adoro on identifying #ERAD as a critical protein quality control checkpoint for T cell development. @eLife @bcmhouston doi.org/10.7554/eLife.69975
Xi Chen retweeted
FEATURED Review in this month's issue: JR Cubillos-Ruiz @JCubRuiz & X Chen @XiChenLab discuss how #ERstress can influence pro-tumoural features of cancer cells & reprogram the function of #immunecells, creating targetable vulnerabilities. go.nature.com/2UKRrMo
@NatResCancer
Excited to share our review with @JCubRuiz on ER stress in cancer @NatureRevCancer under the wonderful guidance of @annaedart ! @bcmhouston
nature.com/articles/s41568-0…
Thank you @Eric_Chevet @costas_koumenis and the anonymous reviewer for the insightful comments!
Join us @bcmhouston. Fantastic department with incredible environment and support to start your lab!
Recruiting faculty @bcmhouston! Multiple assistant prof positions in the MCB dept AND the Stem Cell Cntr! Looking for expertise in #epigenetics #generegulation #cellbio #synbio #organoids #stemcells…
bit.ly/2HyoOhY
bit.ly/363q46V
Why consider BCM? Read on.
Thank you @Goodell_Lab ! So fortunate to be in the amazing MCB department @bcmhouston with enormous support from Peggy and incredible colleagues!
Please give a warm Twitter welcome to @XiChenLab who just joined. -Fantastic faculty member in MCB department @bcmhouston. Beautiful new @NatureCellBio paper on protein QC in #HSCs! Congrats!
Thank you @SignerLab for writing a wonderful and insightful News & Views highlighting our paper @NatureCellBio ! We love the title "ERADicating stem cells from their niche"!
ERADicating stem cells from their niche. Our News & Views on exquisite new work from @XiChenLab in @NatureCellBio on how proteostasis regulation by the ERAD pathway influences the interaction of HSCs with their perivascular niche in the bone marrow. rdcu.be/b7vFR
Very pleased to share our latest work on ER-Associated Degradation (#ERAD) as a critical protein quality checkpoint that controls HSC-niche interaction and determines the fate of HSCs. @NatureCellBio @bcmhouston
nature.com/articles/s41556-0…