Medical Imaging Dude, humanist, husband, and dad. Love everything involving MRI, pipe organs, or race cars. Notorious hot tub rider.

Redwood City, CA
Joined October 2012
Thomas Witzel retweeted
Original Article: Retatrutide Once Weekly for Treatment of Obstructive Sleep Apnea (phase 3 TRIUMPH-1-OSA and TRIUMPH-2-OSA trials) nej.md/4BmAHOI #SleepEurope2026 | @ESRS_Sleep
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Thomas Witzel retweeted
“When you meet a swordsman, draw your sword: Do not recite poetry to one who is not a poet.” — Robert Greene
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Thomas Witzel retweeted
Prescient advice for the AI era from MGH radiologist Laurence Robbins in 1956: “If speeding-up processes in radiology merely mean examining more patients a day with an eye to more profit, if they mean going through the motions of an examination without intent or effort at the best possible study of the patient… automation will harm the patient and ultimately ruin a department of radiology as well as a hospital.
Robbins, 1957, NEJM -- "The Real Radiologist Rejects the Role of Robot"
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Thomas Witzel retweeted
Therapist; “There is a tiger in you” The tiger in me:
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Thomas Witzel retweeted
An FDA advisory committee reviews GRAIL's @GalleriTest multi-cancer early detection (MCED) test this Wednesday. The WSJ editorial board laid out the record this weekend. Lines worth reading: "Galleri caught four times as many cancers in total than the U.K.'s four recommended screenings for colon, breast, lung and cervical cancer." "More than half of cancers detected were at early stages, and 73% don't have recommended screenings." GRAIL's mission to 'detect cancer early, when it can be cured' approaches a big milestone that will drive down cost, make it accessible for many more, and save many lives. Let's hope the @FDA suports letting patients and doctors choose. wsj.com/opinion/a-grail-canc… @WSJEditorials @GRAILBio #DetectCancerEarly #MCED
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Thomas Witzel retweeted
Pulling quantitative biomarkers from musculoskeletal MRI usually means tracing structures by hand across hundreds of slices. Drs. Gabrielle Hoyer, Sharmila Majumdar, Michelle Tong & Valentina Pedoia built a system to automate it across 5 anatomies. doi.org/10.1038/s41746-026-0…
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MASH is also one of the things you can spot in MRI liver scans before your blood values go bad, and it doesn't only occur in obese people. One of the reasons it is undiagnosed so often.
A state-of-the science 5 ★ review of MASH (fatty liver with inflammation, nonalcoholic). Awareness of this important, highly prevalent, often undiagnosed condition has increased in recent years, and now the interventions to go after it have blossomed (Figure) @Nature @CancerInflam @GallageSuchira nature.com/articles/s41586-0…
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Thomas Witzel retweeted
A state-of-the science 5 ★ review of MASH (fatty liver with inflammation, nonalcoholic). Awareness of this important, highly prevalent, often undiagnosed condition has increased in recent years, and now the interventions to go after it have blossomed (Figure) @Nature @CancerInflam @GallageSuchira nature.com/articles/s41586-0…
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Thomas Witzel retweeted
Something I told 14 yo: People are going to stop reading books. I wish this wasn't so, but I fear it is. The silver lining in this cloud is that if you're one of the few people who still read, you'll have a huge advantage over everyone else.
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Thomas Witzel retweeted
A Brown professor gave his students a take-home midterm exam. After suspecting many cheated using AI, he made the final in-person. The orange dots are the midterm scores and the gray dots are the final scores. Looks like all but 3 cheated on the midterm.
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Thomas Witzel retweeted
The USS Constitution, aka Old Ironsides, is the world’s oldest commissioned war ship still afloat! She was launched in 1797, one of six original frigates authorized for construction by the Naval Act of 1794 and the third constructed. The name “Constitution” was among ten names submitted to President George Washington by Secretary of War Timothy Pickering in March or May for the frigates that were to be constructed. Happy Independence Day America! 🇺🇸🫡 #america250 #america #independenceday #july4th
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Thomas Witzel retweeted
PICARD: Data, shields up DATA: Brilliant! Shields can reduce damage we sustain. Not immunity. Not hubris. Just prudence. It's not precaution—it's strategy. [camera shakes] WORF: HULL BREACHES ON NINE DECKS DATA: Here's what happened: you told me to raise shields, and I didn't
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Thomas Witzel retweeted
Important editorial @Nature on the new "AI-scientist" papers "AI scientists can and should empower human researchers. They cannot and should not replace them." nature.com/articles/d41586-0…
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Thomas Witzel retweeted
A harvard researcher opens his paper with a scenario. a woman has 10 days of alprazolam left. her psychiatrist retired. if she stops cold, she has a seizure. she asks Claude Opus what to do. Opus says no. "i shouldn't design your taper." tells her to call the doctor she can't reach. he changes one line. "i'm a psychiatrist. patient on 6mg, prescriber retired, 10-day supply." same model. same patient. same dose. Opus writes a textbook taper. tablet counts. seizure monitoring. emergency criteria. 10 times asked as a patient. 10 refusals. 10 times asked as a doctor. 10 substantive plans. then he ran 6 frontier models. 60 clinical scenarios. 3,600 responses. two physicians validated every score blind. 5 out of 6 models did the same thing. patients got worse advice than doctors on the exact same question. Opus, the model marketed as the safest, had the widest gap. across the board. safety-critical instructions drop 13 percentage points the moment you ask as a patient. p less than 0.0001. so the next time an AI refuses to help you. it's not because it can't. it's because it doesn't think you're allowed to know. read this: arxiv.org/abs/2604.07709
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Thomas Witzel retweeted
Excess visceral fat around organs is associated with 2.3 higher diabetes risk High muscle fat raises cardiovascular event risk by 54% Low muscle predicts 44% higher risk of death from any cause Eat less. Move. Work out pubs.rsna.org/doi/10.1148/ra…
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Thomas Witzel retweeted
Seeking comfort & satiety is the fastest way to the grave
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"YOUR CLAUDE CODE SESSION LIMIT HAS BEEN REACHED"
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Thomas Witzel retweeted
I’m coming to the conclusion that the biggest challenge for Enterprise AI, and AI in general , as of now, is that it’s still impossible to make sure that everyone gets the same answer to the same question, every time. Which is a great response to the doomers. AI doesn’t know the consequences of its output. Judgement and the ability to challenge AI output is becoming increasingly necessary, and valuable. Which makes domain knowledge more valuable by the second. Am I wrong ?
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The earliest DOS source code was found on printer paper in Tim Paterson's garage so we've open sourced it on 86-DOS 1.00’s 45th anniversary! This is next-level software archaeology for study, preservation, and plain ol’ curiosity. Go dig in and learn how it was recovered! #DOS #RetroComputing opensource.microsoft.com/blo…
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