@WinnerLab

Research group of Beate Winner 👩🏼‍🎓, focusing on disease modeling of neurodegeneration using hiPSCs. 👩🏼‍🔬🧠 @UniFAU (posts from lab members)

 Erlangen, Deutschland
stammzellbiologie.uk-erlangen.de
Joined June 2019
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  • Followers546
203Media
Happy to share that our work on in vitro neurotoxicology assessment of an #RNA splicing modulator was published in #iScience: cell.com/iscience/fulltext/S… Joint work with Tom Boerstler, Florian Krach, Jürgen Winkler and Beate Winner 🚀 @Molecular_Neuro @UniFAU #WinnerLab ⬇️

RNA splicing modulator for Huntington’s disease treatment induces peripheral neuropathy

Pharmacology; Natural sciences; Biological sciences; Neuroscience; Cellular neuroscience; Cell biology

cell.com
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In this use case we leveraged the power of #iPSC-derived #neurons and were able to recapitulate adverse event findings arising in #HuntingtonsDisease patients during a #clinicaltrial. ⬇️
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This illustrates the need to complement current non-clinical #toxicology assessments with human model systems for #nucleicacid targeting #medicinalproducts. #science
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Great event organized by a team around our wonderful @NaimeZagha Followed by a discussion with experts and patients 🧑🏻‍⚕️ @CRU_GB_Com @MIB_GuentherLab
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Alpha synulcien targeting NPT100-18A rescues mitochondrial oxidative stress & neuronal degeneration in human iPSC-based #Parkinsons; First mechanistic insights into how a compartment-specific antioxidant effect in mitochondria might be involved in MoA bmcneurosci.biomedcentral.co…
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Very excited that our study in #BMCNeuroscience @BioMedCentral is out! We provide the first insights into the compartment-specific protective effects of #alphasynuclein anti-oligomerisation compounds in human dopaminergic neurons in the context of #ParkinsonsDisease. @WinnerLab
The Science of Parkinson's@ScienceofPD29 Jan 2025
Alpha synulcien targeting NPT100-18A rescues mitochondrial oxidative stress & neuronal degeneration in human iPSC-based #Parkinsons; First mechanistic insights into how a compartment-specific antioxidant effect in mitochondria might be involved in MoA bmcneurosci.biomedcentral.co…
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Winner_Lab retweeted
GRK2162@grk216228 Jan 2025
🌟Join us at the 3rd International Symposium: Developmental Processes in CNS Plasticity and Pathogenesis!🌟 🗓️April 9-11, 2025 📍Erlangen, Germany ✏️Register here: bit.ly/4jvs4Z5 #Neurogenesis #DevelopmentalBiology #NeuralCircuit #CNSdisorders #GRK2162 #Symposium
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We are excited to introduce first-of-a-kind immunofluorescent probes to visualize RNA in cells! @NAR_Open Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells academic.oup.com/nar/article…

Synthetic anti-RNA antibody derivatives for RNA visualization in mammalian cells

Abstract. Although antibody derivatives, such as Fabs and scFvs, have revolutionized the cellular imaging, quantification and tracking of proteins, analogo

academic.oup.com
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An integrated transcriptomic cell atlas of human neural organoids | Nature nature.com/articles/s41586-0…

An integrated transcriptomic cell atlas of human neural organoids

Nature - A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary and organoid...

nature.com
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The position is still available!! Plz RT and apply!! Send DM
Tomohisa Toda@TomohisaToda23 Aug 2024
#JobAlert join us as a ERC-funded postdoc to uncovered long-lived RNA dependent epigenetic regulation in brain aging @UniFAU,@MPZ_PhysMed, #RNA #chromatin #epigenome #aging. Plz check todalab.com. Dm if you are interested in. And Plz RT!!!

The Toda Lab

Neural Epigenomics lab @ FAU Erlangen and MPZ-PM

todalab.com
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Good morning! ☀️ Off to a fresh new week full of exciting science 🧬 🔬 #WinnerLab
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Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown biorxiv.org/content/10.1101/…

Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown

Neurons rely on mRNA transport and local translation to facilitate rapid protein synthesis in processes far from the cell body. These processes allow precise spatial and temporal control of transla...

biorxiv.org
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Looking back at our #ScienceSlam last night @ewerk_erlangen 🚀💪🏻 Thanks to everyone who joined us, thanks to the moderator @schroep, the organization team @CRU_GB_Com, and of course a huge thank you to the slammers! @krummla @bruno_ghirotto @DuarteLEG @vivien_ruder @klarametzner
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It was a fabulous opening ceremony for the Max-Planck-Zentrum für Physik und Medizin! Many thanks to all participants who made this day so special! 🙏 We are looking forward to the research at the MPZPM taking off! 💨 #Research #Physics #Medicine #Inspire #MPZPM @UniFAU
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Physics 🤝 medicine Scientists specializing in physics, biology & medicine will be working at the Max-Planck-Zentrum für Physik und Medizin (MPZPM) to shape the future of medical research. In 7 days, we will be celebrating the opening of the MPZPM! 👉bit.ly/About-MPZPM
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👏🏻 See you at the Science Slam!
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The event will be in English. Tickets available from September 10th—grab yours quickly as spots are limited. Free entry! Tickets at: eveeno.com/gb-forinter-scien… @WinnerLab @MIB_GuentherLab @UniFAU
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🚀Our 2021 Science Slam was a hit with 500+ attendees!🎉Now, join us on #September24th at 6 p.m. at E-Werk Erlangen for more exciting discoveries! 🎙️ Scientists 👨‍🔬👩‍🔬 will dive into stem cell biology 🔬 and gut-brain communication, plus some fun surprises ;)#ScienceSlam
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Congrats Beate 👏🏻👏🏻👏🏻
Joachim Hornegger@Hornegger3 Sep 2024
#FAUcongrats: Beate Winner is now appointed W3 Professor at #FAU's Medical Faculty. Beate’s scientific research focuses on human stem cell models that can used to understand the disease pathologies of neurodegenerative disorders. @UniFAU @WinnerLab 👏👍
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We are back! -- Science Slam 2024 -- 🚀🎙️ fau.tv/clip/id/53668 When? September 24th, 2024; starting at 6pm Where? @ewerk_erlangen Get your ticket (soon) here: eveeno.com/gb-forinter-scien… @CRU_GB_Com @MIB_GuentherLab

Science Slam 2024 [ID:53668]

Entdecken Sie Videos und Livestreams der FAU .

fau.tv
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