@WeersmaLab

Gastroenterologist, Translational research, microbiome & integrative omics analyses, host-microbe interactions in the context of IBD and other chronic diseases

 Groningen, Nederland
Joined October 2022
  • Tweets193
  • Following170
  • Followers430
36Media
Dear all, we decided to leave twitter / X You can find us on Bluesky: weersmalab.bsky.social
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Our Consensus statement on #microbiome testing in clinical practice is out in @LancetGastroHep! authors.elsevier.com/a/1kDP5… Here we recommend how to standardise the framework for test release (indications, pre-testing protocols, sequencing & analysis, result reporting). A thread🧵⬇️
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WeersmaLab retweeted
Gut Journal
@Gut_BMJ11 Nov 2024
#GUTImage from the #RecentAdvancesInClinicalPractice paper by @arnauvich et al on "Untargeted faecal metabolomics for the discovery of biomarkers and treatment targets for inflammatory bowel diseases" via bit.ly/4dyIID3 @WeersmaLab #IBD
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Congratulations to Laura Bolte @umcg. Cum Laude distinction for her PhD studying the relation between #diet #microbiome and #immunity in #ibd and response to immune checkpoint inhibition. Work in her PhD thesis has been published in @NatureMedicine @Gut_BMJ and @JAMAOnc
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📢 New Study Alert! 📢Happy to share the latest results from the Lifelines NEXT Mother-Infant cohort! (1/8). Here we profile the gut microbiome in 4,577 longitudinal samples from 714 mother-infant pairs, from 12 weeks of pregnancy to 1 year post-birth doi.org/10.21203/rs.3.rs-533…
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I am incredibly proud that 2 out of the 5 top abstracts #UEGWeek are from our department @umcg (out of >3500 abstracts). Huge congratulations to @BourgonjeArno and Anne van der Waai for their groundbreaking work and this important recognition! @my_UEG @LifelinesNL @researchumcg
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WeersmaLab retweeted
Gut Journal
@Gut_BMJ28 Oct 2024
#GUTImage from the #RecentAdvancesInClinicalPractice paper by @arnauvich et al on "Untargeted faecal metabolomics for the discovery of biomarkers and treatment targets for inflammatory bowel diseases" via bit.ly/4dyIID3 @WeersmaLab #IBD
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Amazing meeting at the Paris Immuno-Oncology Conference 2024! So much food for thought from top leaders in microbiome and immunology: @EranElinav, @derosa__lisa, @nsegata, @WeersmaLab, and more. Honored to present our latest work published in @NatImmunol with @julienCMarie1.
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I am incredibly proud that 2 out of the 5 top abstracts #UEGWeek are from our department @umcg (out of >3500 abstracts). Huge congratulations to @BourgonjeArno and Anne van der Waai for their groundbreaking work and this important recognition! @my_UEG @LifelinesNL @researchumcg
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WeersmaLab retweeted
Gut Journal
@Gut_BMJ14 Oct 2024
#GUTImage from the #RecentAdvancesInClinicalPractice paper by @arnauvich et al on "Untargeted faecal metabolomics for the discovery of biomarkers and treatment targets for inflammatory bowel diseases" via bit.ly/4dyIID3 @WeersmaLab #IBD
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Join us on October 13 for the presentation of our Top Abstract Prize Awardee, Arno R. Bourgonje: CROHN'S DISEASE AND ULCERATIVE COLITIS EXHIBIT PRE-DIAGNOSTIC ANTIBODY SIGNATURES WITH SHARED AND DIVERGENT CHANGES TOWARDS DISEASE ONSET 🔬 👉 bit.ly/3yIvcOg #UEGWeek
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The gut microbiome acetyltransferase genes were involved in the metabolism of 5-ASA in IBD. However, new findings from @WeersmaLab et al. didn't replicate the original findings: gut.bmj.com/content/early/20…
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WeersmaLab retweeted
Gut Journal
@Gut_BMJ12 Sep 2024
#GUTImage from the paper by @CasSwarte et al on "Multiple indicators of gut dysbiosis predict all-cause and cause-specific mortality in solid organ transplant recipients" via bit.ly/3LcQlTL @jingyuan_fu @HarmsenHermie @WeersmaLab
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In contrast to previous reports we found limited predictive value of the gut #microbiome (and #metabolome) for response to biological therapy in #IBD Still small sample sizes but relatively similar to other studies. @GroMicrobiome @umcgmdl @researchumcg www-tandfonline-com.proxy-ub…
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here's the working link to the paper (open access) tandfonline.com/doi/full/10.…

Limited predictive value of the gut microbiome and metabolome for response to biological therapy in...

Emerging evidence suggests the gut microbiome’s potential in predicting response to biologic treatments in patients with inflammatory bowel disease (IBD). In this prospective study, we aimed to pre...

tandfonline.com
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Exploring the previously reported gut #microbiome acetyltransferase genes involved in metabolism of 5-ASA in #ibd we could not replicate the original findings from @NatureMedicine in our Dutch 1000IBD cohort. More work needed. @GroMicrobiome gut.bmj.com/content/early/20…
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WeersmaLab retweeted
Gut Journal
@Gut_BMJ28 Aug 2024
#GUTImage from the paper by Gabriels et al entitled "Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease" via bit.ly/3YIzWP0 @wouternagengast @researchumcg #IBD #Vedolizumab
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(1/6) 📢 New Study Alert! In our randomized controlled trial we compare the gut microbiomes of infants whose mothers received prophylactic antibiotics pre-incision versus post umbilical cord clamping.🤰 doi.org/10.1016/j.chom.2024.…
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WeersmaLab retweeted
Gut Journal
@Gut_BMJ18 Jul 2024
#GUTPressRelease #GUTInTheNews paper by @CasSwarte et al on "Multiple indicators of gut dysbiosis predict all-cause and cause-specific mortality in solid organ transplant recipients" via bit.ly/3LcQlTL @jingyuan_fu @HarmsenHermie @WeersmaLab
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Time to slice some fresh ideas…gut microbiome ,genes, IBD …great to reunite with our team & look forward for more learnings & collaborations @DrThelma @GarimaJuyal @dr_singh_gastro @WeersmaLab @RGacesa @Dr Ajit Sood
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