The Supramolecular Engineering Lab Notre Dame Dept. of Chemical and Biomolecular Engineering

Notre Dame, IN
Joined November 2015
The @WebberLab is looking to hire a synthetic supramolecular chemist for a project to identify and screen new macrocycles for biologically relevant recognition. Please send inquiries to me via email, including a CV and statement of research accomplishments.
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We were pleased to host Prof Markita Landry (@Landry_Lab) from @UCBerkeley to celebrate her receipt of the 2024 Thiele Lectureship from @NDCBE. Prof Landry treated us to an exciting talk on imaging neurochemistry using nanomaterial probes. Congratulation!
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Happy to share latest @WebberLab paper from Matt Sis and team out today in @MacroJrnls_ACS: "Iterative Design Reveals Molecular Domain Relationships in Supramolecular Peptide–Drug Conjugates" to explore molecular design in this class of molecules. doi.org/10.1021/acs.biomac.4…
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Congrats to the @WebberLab’s 5th PhD, @SihanYu_, who defended her stellar PhD work today! Hannah led our groups glucagon work and had a number of nice papers, including two this year: doi.org/10.1002/adma.2023114… (Adv Mat) & doi.org/10.1021/jacs.3c13139 (JACS). Congrats Hannah! 🎉🎉🎉
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Happy to share our latest @WebberLab @NDCBE publication led by @ZhouYeLab out today in @AdvSciNews Advanced Functional Materials on "Implications of Supramolecular Crosslinking on Hydrogel Toughening by Directional Freeze-Casting and Salting-Out" [1/3] doi.org/10.1002/adfm.2024026…
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Check out our latest @WebberLab @NDCBE paper out today in @ACS_ANM on "Capture and Detection of Fentanyl with Thiolated Cucurbit[7]uril Macrocycles on Silver Nanoparticles" on collaborative with our @NotreDame colleagues in the Camden lab. doi.org/10.1021/acsanm.4c014…
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Happy to share our newest @WebberLab paper out today in Journal of Materials Chemistry B @JMaterChem on "Using a Biocatalyzed Reaction Cycle for Transient and pH-Dependent Host–Guest Supramolecular Hydrogels" led by @NDCBE PhD Student Bo Su. [1/3] doi.org/10.1039/D4TB00545G
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Happy to share our latest paper by @SihanYu_ and the team out today in @J_A_C_S on "Glucose-Driven Droplet Formation in Complexes of a Supramolecular Peptide and Therapeutic Protein" doi.org/10.1021/jacs.3c13139 [1/3]
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Thanks to @ASEE_DC for award of the 2024 Curtis McGraw research award! Happy to represent @NDCBE @NDengineering @UNDResearch and have the @WebberLab’s research recognized.
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Perhaps the most impressive component of this work was structural cryoEM to elucidate the packing of these oligopeptides into nanocoils. Thanks to Ravi Sonani and Ed Egelman from @UVA for this beautiful data! [3/4]
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Happy to share our latest work by @SihanYu_ @ZhouYeLab and a great team published today in Advanced Materials @AdvSciNews entitled "Glucose-Triggered Gelation of Supramolecular Peptide Nanocoils with Glucose-Binding Motifs" doi.org/10.1002/adma.2023114… [1/4]
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Happy Holidays from the @WebberLab . We gathered last week for a team dinner to celebrate the end to a successful year.
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