skyfall retweeted
We’re giving away a custom, crystal-white modded GAME BOY Color, with an included retro grip case and USB-C charging. 💎⚡️
✅ Follow @retro_dodo
✅ Share/Retweet this post
✅ Comment with your favourite retro game of all time. 🕹️
Winner announced in 7 days. 1 entry per person, spam/Ai will be disqualified. Worldwide shipping. 🫡🌍 Picked at random.
Check out BrickBoy — The kit that makes the LEGO® Game Boy come alive by Substance Labs on @Kickstarter kickstarter.com/projects/bri…
skyfall retweeted
Morph 2K pre-orders are now open!
A $199 analog video scaler for retro gaming with composite, S-Video, SCART, component, and VGA support. Incredible video quality, CRT simulation, auto-sampling, Wi-Fi updates, and more.
To celebrate launch day, we're giving away one Morph 2K.
To enter:
✓ Follow @PixelFXco
✓ Like & repost this post
Winner selected June 20th.
pixelfx.co/product-page/morp…
skyfall retweeted
Remember her name: Aliya Rahman
Her testimony is everything. It deserves to be heard, by everyone. Decide for yourself.
It’s powerful. It’s gut-wrenching. And no one should have to survive what she did.
God bless this woman.
ICE MUST GO‼️
skyfall retweeted
Appalled to see the Telegraph giving Aseem Malhotra a platform today. He has spread increasingly dangerous vaccine misinformation with impunity.
@gmcuk’s failure to remove him from the register is every bit as appalling. A spineless dereliction of duty.
The British media keeping up the negative stories about Spurs since Wednesday @spursshow @1MickyHazard
#COYS
skyfall retweeted
Something that the Lucy Connolly case has illustrated - something that is well known to those who work in criminal justice but often overlooked in public debate - is the complexity and nuance in the lives and characters of people appearing before the courts.
A short 🧵👇
skyfall retweeted
After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology. Lately, I’ve focused on unravelling the reasons why diets high in ultra-processed food are linked to epidemic proportions of chronic diseases such as diabetes and obesity. Our research leads the world on this topic.
Given recent bipartisan goals to prevent diet-related chronic diseases, and new agency leadership professing to prioritize scientific investigation of ultra-processed foods, I had hoped to expand our research program with ambitious plans to more rapidly and efficiently determine how our food is likely making Americans chronically sick.
Unfortunately, recent events have made me question whether NIH continues to be a place where I can freely conduct unbiased science. Specifically, I experienced censorship in the reporting of our research because of agency concerns that it did not appear to fully support preconceived narratives of my agency’s leadership about ultra-processed food addiction.
I was hoping this was an aberration. So, weeks ago I wrote to my agency’s leadership expressing my concerns and requested time to discuss these issues, but I never received a response. Without any reassurance there wouldn’t be continued censorship or meddling in our research, I felt compelled to accept early retirement to preserve health insurance for my family. (Resigning later in protest of any future meddling or censorship would result in losing that benefit.) Due to very tight deadlines to make this decision, I don’t yet have plans for my future career.
The NIH has been a wonderful place because it allows scientists to take risks, form unique collaborations, and do studies difficult to conduct elsewhere. I’m proud of what we’ve accomplished and I’m fortunate to have had such wonderful colleagues and scientific collaborators. I hope to someday return to government service and lead a research program that will continue to provide gold-standard science to make Americans healthy.
skyfall retweeted
There has been so much noise about this KETO CTA study it is becoming overwhelming but I want to raise a concern that I am not sure others have voiced, at least that I have seen. Specifically, if you look at the patient flow diagram from the supplement, there is no information on how many people were screened and not enrolled (screen fails)
skyfall retweeted
The pre-registered primary outcome was percent change in non-calcified plaque volume. Trying to say you reported this through the below graph—which in no way reports this—is intellectual dishonesty and this should not have slipped past editors/reviewers.
clinicaltrials.gov/study/NCT…
skyfall retweeted
If you call yourself a scientist but omit reporting the primary outcome in your study 🚩🚩🚩🚩
skyfall retweeted
Three years ago they discussed the inclusion criteria in detail over internal emails. It didn't make sense to group people with CAC alongside people without CAC, and also they couldn't investigate either in isolation because they just didn't have enough people in the cohort. The only way to have enough participants to have statistical power would be to lump them all together. But if they did that, the results would also be practically useless.
They chose to lump them all together, thus creating useless results that are basically uninterpretable to anyone with domain knowledge, but they're still keen on calling it a groundbreaking study. At this point, I'm convinced that it's all a big PR project, and very little of anything else. It's just a big game to inflate Feldman's LMHR branding. It's really difficult for me to interpret this project as anything other than that.
They're just interpreting the results in any way they can to salvage their narrative and drive traffic. Even to the point where their primary outcome, as specified in their preregistration, is not the data point that they're making all of their social media noise about. They've barely even made a sound about it, and instead they're focusing on the statistical relationship between ApoB and plaque progression.
Nowhere in the preregistration is this analysis mentioned as a second or even third order goal. Their preregistration has a single primary outcome and that's all, and if they actually focused on the primary outcome that they preregistered, they wouldn't be able to report the results in a way that is as rhetorically powerful, because those results actually weren't very good for keto. In fact, they're awful.
If you remember back a few years, the primary thrust of this study was pitched as being a prospective study on LMHRs that would be compared to likewise non-keto cohorts for the purposes of investigating differences in plaque progression rates. After all these years and all of that consistent social media hype, they finally have those data, and instead of making those data front and center in their manuscript, they stuff those results at the ass end of the supplement (where only a small percentage of people are likely to look).
This was 100% intentional, because with respect to plaque progression, those results actually make it look like being an LMHR is worse than being a metabolically unhealthy person on a standard American diet, independent of ApoB. They've completely shifted the goalpost away from what they said the study was going to be (in both their preregistration and their social media hype) to something that they think will simply salvage what's left of their narrative. And it's disgusting.
The correct way to respond to this is just to shame them, throw their shitty results in their faces at every opportunity, and laugh at them.
skyfall retweeted
Of course this is incorrect. They hid the primary outcome of the study which showed on average a lot of progression. More than an average person on the ol SAD (standard American diet).
