This guideline is going to be so important for our people living with diabetes and renal disease @DSNforumUK @UKCPADiabetes @DiabetUK @drpatrickholmes @drkevinfernando @MikeWMLeeds @PNewlandJones @pcdsociety

Our West Yorkshire Guideline for CKD approved today at APC. This guidance should help us screen, refer & optimise care for people living with CKD. Thank you to all the brilliant minds who contributed and to Andrew Frankel and the imperial team for the inspiration

It’s out .. NICE TA Tirzepatide … the era of the multi incretin begins … nice.org.uk/guidance/ta924/r…

The TEDDY study … so only testing GADs would lead to us missing 39% of onset .. wonder if that’s the same for adults ?? Interesting results on links to childhood viral exposure .. very different results depending on age #EASD2023

Still more work to do .. lovely to see my alma mater @UW with Dr Zhao’s incredible collaboration with this work on the TEDDY study

Brilliant Claud Bernard lecture today #EASD2023 .. staging autoantibody onset could help is treat this more effectively and hold off development of symptomatic T1DM

Data from a pooled analysis supports a renal outcome trial for Tirzepatide , particularly compelling improvements seen in those with pre existing CKD #EASD2023

Interesting exploratory analysis of SURPASS 2 looking at sustained reduction of HbA1c and weight .. slightly interesting results for composite .. longer studies would be helpful I think #EASD2023

Really nice network meta analysis .. let’s not forget we don’t use 2mg Semaglutide in the UK ..so for us Tirzepatide is better for HbA1c and weight loss than anything else we have currently available for management

Exogenous ketone supplementation .. does it help with post prandial glucose excursions ? Yes in people NOT living with T2DM or with those with obesity without diabetes .. you do not see this helping in T2DM .. why ??!! 🤔 dose ? Administration route/formulation? #EASD2023

sPIF ,there may be a new insulin secretagogue in the pipeline .. IDE is the target .. very interesting presentation #EASD2023

favourite study so far .. GLP-1 pancreatic gene therapy for a durable therapy solution .. 1 injection !! all that knowledge about GLP-1 and looking at how to create a lasting solution .. no signs of pancreatic Ca/pancreatitis in animal studies .. really exciting !!#EASD2023

EMINENT study .. electroporation therapy in addition to GLP-1 , can help avoid insulin #EASD2023 .. one time procedure , so could help with compliance

Brilliant editorial .. there is opportunity to revisit with other avenues ! @JaneDiggle1 thank you 🙏

Really really excited about this job !!! Diabetes Pharmacist Role in a PCN … this innovative role is just the start and we can’t wait for the post holder to join #diabetesleeds #onesystem ⁦@UKCPADiabetes⁩ ⁦@LeedsHCP⁩ ⁦@WYpartnership⁩ beta.jobs.nhs.uk/candidate/j…