
Wetenschapper, vader, vogelaar / Scientist, dad, birder - Chemical Immunology @VerdoesLab @TIL_Radboudumc
Joined November 2019
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Martijn Verdoes retweeted
Very happy and grateful that our cover art has been selected for the September issue of @nchembio 🤩
nature.com/articles/s41589-0…
Our September issue is live!
nature.com/nchembio/volumes/…
The cover image by Petruzzella et al. depicts different non-natural peptide inhibitors bound to cathepsin S, representing a few possible outcomes of site saturation mutagenesis screening.
Martijn Verdoes retweeted
Great to see our probe have such great results in the phase II trial with @VergentBio. Check out the paper.
Phase 2 data published in @STS_CTsurgery journal @annalsthorsurg show VGT-309 may help surgeons see difficult-to-find and previously undetected tumors in real-time during #MIS and robotic-assisted surgery.
bit.ly/4bNYCIE
#TumorVisualization #LungCancer
Martijn Verdoes retweeted
Excited to announce that as of this week, the van Mierlo lab is officially open in the dpt. of Medical BioSciences, @RIMLSInstitute , @radboudumc Nijmegen. Quantitative (prote)omics, tumor immunology, and a bit of epigenetics. Exciting times ahead #newPI .
Martijn Verdoes retweeted
My latest blog now online on the website of @vogelnieuws - vogelbescherming.nl/actueel/…
How @Deceptiontours birding weekends on Vlieland let to come eye-to-eye with the Monkey-eating Eagle on the Philippines.
(In Dutch, but maybe @ChatGPTapp is kind)
@VerdoesM with a Pallid Swift
Martijn Verdoes retweeted
Live from the field.
@VerdoesM just photographed this male Gough Bunting on Gough island in the middle of the southern Atlantic islands during the #AtlanticOdyssey. One of the remotest places on earth.(Just for fun, look it up!)
#BirdsSeenin2024
#Gough
#tristandacunha
Martijn Verdoes retweeted
What is happening? Something new... come join us jobs.ac.uk/enhanced/linking/… @imperialcollege @QMUL @emblebi
Martijn Verdoes retweeted
Becker et al. showed that patients with NSCLC had increased blood levels of CD1c+CD14+ DC3s expressing an immunosuppressive phenotype and reduced T cell stimulatory activity. bit.ly/3SsRqdr @TIL_Radboudumc
Martijn Verdoes retweeted
Thanks to @9NewsMelb for highlighting our study of VGT-309 with @StVincentsMelb, as we aim to help surgeons see difficult-to-find tumors in real time during surgery. Check out the story below! #lungcancer #innovation @msanto92
Martijn Verdoes retweeted
Phase II clinical trial data just reported for our covalent cathepsin probe by @VergentBio. Exciting! businesswire.com/news/home/2…
Martijn Verdoes retweeted
1⃣We defined the metabolome of M-CSF- vs GM-CSF-differentiated human macrophages.
2⃣We discovered adenine to be more abundant in M-CSF macrophages.
3⃣Adenine suppressed inflammation and elicited metabolic quiescence
Mechanism to be uncovered...
➡️sciencedirect.com/science/ar…
Martijn Verdoes retweeted
Save the date!
The ICI Chemical Immunology Conference 2024 will take place on June 28th at Naturalis, Leiden, The Netherlands.
Stay tuned for the program.
Martijn Verdoes retweeted
Great talk by @kimbonger @BongerLab at #EFMCISCB2023. She talked about her group's exciting research on new tools to better understand biology including using THRONCAT to study newly synthesized proteins in cells. doi.org/10.1038/s41467-023-3…
Martijn Verdoes retweeted
Overpublishing puts enormous stress on students and PIs.
And brings tons of money to publishers in STEM.
A new study shows that the number of papers is increasing FASTER than the number of #PhD graduates.
It’s an amazing work with very useful statistics. Huge kudos to the authors!
▫️
Main outcomes:
1️⃣ In 2022 the number of articles is 47% higher than in 2016. The amount of writing, reviewing and editing workload per scientist is increased enormously.
2️⃣ “Special issues” is a strategy for publishing lots of papers with reduced review time. This is possible due to the “publish or perish” pressure and clearly benefits the publishers.
3️⃣ The publishing time varies widely!
MDPI = 37 days. Frontiers = 72 days. Elsevier = 134 days. Springer = 157 days. Nature = 185 days.
4️⃣ The article rejection rates do not seem to correlate with publisher growth. However, rejection rates decline with increased use of special issue publishing.
5️⃣ Certain for-profit gold-open-access publishers create an increasing number of special issues, with uniquely reduced turnaround times, and in specific cases, high impact inflation and reduced rejection rates.
6️⃣ The authors suggest a new metric - Impact Inflation, which is reflected in self-citation within the same journal. For example, MDPI has a high impact inflation due to excessive self-citation compared to other publishers.
Conclusions and my opinion:
- Scientists have to spend a lot more time on reviewing and writing than before (on average).
- The more papers are published, the more the quality is compromised.
- Scientific progress has become partially bound to the business models of publishers and their revenue (a sad reality today).
- There is a huge lack of transparency. Much of these data had to be ‘web-scraped’ from numerous sources in order to get a full picture. We clearly need regulators to mandate open access to publisher’s statistics.
- Reduce the number of special issues! Those typically have low standards.
▫️
Science, publishing and funding make a trio that is very hard to disentangle.
However, research quality is controlled by the community.
This is why preprint + community review can make a big difference.
#AcademicTwitter #AcademicChatter
Martijn Verdoes retweeted
11th - 13th October was this years IMAGINE! Autumn Retreat. This event is organised every two years. This year we were in Vinkeveen Haven!
Nearly all PhD and postdoc positions are now filled. It was great to meet you all there!
Martijn Verdoes retweeted
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
Martijn Verdoes retweeted
"Straks pakt een wolf een kind!".
Het vreemde is, honden doen dat al, maar daar hoor je amper iemand over.
Martijn Verdoes retweeted
Today we presented new data at the @IASLC 2023 World Conference on #LungCancer providing compelling evidence that VGT-309 increases the potential that surgeons can identify all tumor tissue during minimally invasive and robotic surgery. #WLCL23 Read more: vergentbio.com/news-2023-sep…
Martijn Verdoes retweeted
Great news for the use of our cathepsin activated optical probes for surgical navigation. Great work @VergentBio. Can’t wait to see the next data set!
Today we presented new data at the @IASLC 2023 World Conference on #LungCancer providing compelling evidence that VGT-309 increases the potential that surgeons can identify all tumor tissue during minimally invasive and robotic surgery. #WLCL23 Read more: vergentbio.com/news-2023-sep…
Martijn Verdoes retweeted
We will present Phase 2 clinical data for VGT-309 at the @IASLC 2023 World Conference on Lung Cancer on Sept. 11, sharing findings from the first surgical study using our novel, tumor-targeted fluorescent imaging agent. Read more: vergentbio.com/news-2023-aug… #WCLC23





































