Scientist by day. Lover of mosquitoes and tacos. Caffeine and history buff. Unlikely midwesterner. Thoughts are my own.
Ames, IA
Joined August 2015
- Tweets2.4K
- Following882
- Followers2.3K
- Likes7.1K
Ryan Smith retweeted
🦟 We've just published the world's first head-to-toe single-cell atlas of the Aedes aegypti mosquito in @CellCellPress! The #MosquitoCellAtlas maps 69 cell types across 19 tissues, revealing surprising biology: mosquitoes taste with their legs (more than we thought), glial cells (not neurons!) dramatically rewire after blood meal & males/females are nearly identical at the cellular level—with intriguing exceptions. Read it here: cell.com/cell/fulltext/S0092…
Ryan Smith retweeted
Drs David Hall & @Vectorimmunlab highlight @merkling_lab & colleagues’ @CellGenomics article on #mosquito cellular responses in #midgut & #fatbody after #bloodfeeding. #Aedes #aegypti #scRNAseq #Metabolomics @IowaStateU @institutpasteur @univ_paris_cite
authors.elsevier.com/a/1lbEr…
Ryan Smith retweeted
I am thrilled to present the Mosquito Cell Atlas! We analyzed 367K nuclei from 19 tissues in male & female mosquitoes, creating a comprehensive resource for vector biology & infectious disease research.
Plus we made some surprising discoveries! 🦟🧵
biorxiv.org/content/10.1101/…
1/n
ALT Photos of Aedes aegypti female (left) and male (right). Numbers indicate location of collected tissues (listed in legend boxes). Photos by Alex Wild.
Ryan Smith retweeted
BIG NEWS! The Mosquito Cell Atlas preprint is live! 🦟🧬 My first senior author paper! Massive and accessible snRNA-seq dataset and a lot of cool mosquito biology. A true collaborative achievement! #MCA
biorxiv.org/content/10.1101/…
See @oliwiagoldman thread ⬇️
I am thrilled to present the Mosquito Cell Atlas! We analyzed 367K nuclei from 19 tissues in male & female mosquitoes, creating a comprehensive resource for vector biology & infectious disease research.
Plus we made some surprising discoveries! 🦟🧵
biorxiv.org/content/10.1101/…
1/n
ALT Photos of Aedes aegypti female (left) and male (right). Numbers indicate location of collected tissues (listed in legend boxes). Photos by Alex Wild.
Ryan Smith retweeted
I am super excited to share our latest review about the effects of blood-feeding and infection on arthropod (mosquitoes and ticks) hemocytes.
Huge thanks to @theticklab and my mentor, @Vectorimmunlab, for their efforts in putting this together..
sciencedirect.com/science/ar…
Ryan Smith retweeted
🎉Congratulations Dr. Ryan Smith @Vectorimmunlab, Iowa State U, for receiving the 2024 ACME Breakthrough in Medical Entomology Award.
🥇The award was presented by outgoing Chair @DrAdrianaTroyo at the awards ceremony during ACME Symposium II @ASTMH #TropMed24, with @hamer_lab
Ryan Smith retweeted
Free alternative to BioRender: BioArt Source
2,000+ science and medical art visuals of high-quality, scientifically accurate vectors, icons, and brushes is freely available within the public domain
bioart.niaid.nih.gov/
Ryan Smith retweeted
Check out this cool work from @samantsidis and @Vectorimmunlab using An gambiae transgenic lines we helped them create!
With some help from @UMDITF, we tested multiple candidate hemocyte promoters to drive fluorescent markers in mosquito immune cells. While not every promoter worked, we did have success with three promoters, SPARC, PPO6, and LRIM15
Ryan Smith retweeted
Now, this project has been one of my favorites during my postdoc with @Vectorimmunlab . Not only because it brought me stateside but also because I got to use groundbreaking techniques and dive into the world of mosquito immune cells.
Excited to share the latest preprint from the lab in which we made trangenic mosquitoes that express various immune cell markers and use cutting-edge flow cytometry techniques to examine mosquito immune cell populations! Awesome work from @samantsidis!
biorxiv.org/content/10.1101/…
Ryan Smith retweeted
Long-term mosquito sampling in Iowa offers crucial insights on the ecology of Anopheles species that could transmit the malaria parasite in the U.S.
🔗 How One State's Mosquito Data Could Reduce Risk of Malaria Returning to U.S. entomologytoday.org/2024/10/…
Ryan Smith retweeted
Come work with us! Our department @kstatebio is recruiting for a tenure-track faculty position broadly in the MCDB realm. Please help spread the word @ACME_ASTMH @MUVE_ESA @EsaPbt @_SOVE_
We are hiring! The Division of Biology at Kansas State has a tenure-track faculty position open in Integrative MCDB. Apply via tinyurl.com/2dv9kub8
Please RT!
Ryan Smith retweeted
Parasite, Fungal & Vector database resources will be coming back online … fill out the form at VEuPathDB.org to be kept informed, and an anonymous survey to help define the future
🔗veupathdb.org/
Ryan Smith retweeted
My commentary on the closure of @VectorBase. Join me in rallying for its sustainable continuation. Comment, repost, and circulate. Let’s ensure this vital resource remains accessible for our global #VectorBiology research community.
Ryan Smith retweeted
"Nothing in vector biology makes sense except in the light of @VectorBase... and now the lights are going out. 💡🔌 #SaveVectorBase
Ryan Smith retweeted
Only 5 more days! Every morning I am reminded that @VectorBase is going away! @NIAIDFunding what were you thinking?!? This resource is critical to so many research labs. MUVE_ESA @ACME_ASTMH
Ryan Smith retweeted
Iowa program tracks mosquito trends over 50 years: 2024 a big year - Iowa State University Associate Professor Ryan Smith. AMES, IA – Despite a slow start following several dry years, mosquito populations in Iowa ... - ift.tt/uHKa450
Ryan Smith retweeted
Thrilled to share our latest research in @NatureComms.
We performed single-cell analysis to computationally define new “driver genes” and study gene regulatory networks involved in male and female cell fate in Plasmodium falciparum gametocytes.
nature.com/articles/s41467-0…
Ryan Smith retweeted
Wow, this is mind blowing. Oxygen transport by insect blood cells!
Excited to share our latest work on the role of Drosophila crystal cells in respiration, published today @Nature! Huge congrats and many thanks to all the authors- Dr. Mingyu Shin, Eunji Chang, and Daewon Lee and our collaborators. (1/3)
doi.org/10.1038/s41586-024-0…
Ryan Smith retweeted
TNF signaling mediates cellular immune function and promotes malaria parasite killing in the mosquito Anopheles gambiae dlvr.it/T6TDBR @biorxivpreprint
