@VachetLab

Vachet Research Group at the University of Massachusetts Amherst: mass spectrometry, protein amyloid formation, nanomaterials in biology, protein therapeutics

 Amherst, MA
chem.umass.edu/~vachet/index.html
Joined September 2017
  • Tweets227
  • Following184
  • Followers491
111Media
Vachet Lab retweeted
ACS Nano@acsnano19 Jun 2024
A team led by @VachetLab of @UMassChemistry @UMassAmherst developed an imaging method that utilizes metal-coded mass tags and #LAICPMS to quantify the site-specific concentrations of proteins and their #nanocarriers in tissues. Read this article here: go.acs.org/9SN
TOC image from the article

ALT TOC image from the article

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Congrats our @UWMadisonChem grad student Cam on successfully passing the RP exam and officially achieving the PhD Dissertator status 🥳🥳🥳 Well done!!! – at Wisconsin, USA
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The @asmsnews election ballots are out! Check that email inbox
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In this article, Park et al. in collaboration with the @VachetLab, report a combination therapy for biofilm infections. Silver nanoclusters and eugenol integrated into polymeric biodegradable nanoemulsions demonstrated synergistic antimicrobial activity. pubs.acs.org/doi/10.1021/acs…

Synergistic Treatment of Multidrug-Resistant Bacterial Biofilms Using Silver Nanoclusters Incorpo...

Abstract. Multidrug resistance (MDR) in bacteria is a critical global health challenge that is exacerbated by the ability of bacteria to form biofilms. We

pubs.acs.org
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Membrane Protein Binding Interactions Studied in Live Cells via Diethylpyrocarbonate Covalent Labeling Mass Spectrometry #AC pubs.acs.org/doi/10.1021/acs…

Membrane Protein Binding Interactions Studied in Live Cells via Diethylpyrocarbonate Covalent...

Abstract. Membrane proteins are vital in the human proteome for their cellular functions and make up a majority of drug targets in the U.S. However, charac

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Vachet Lab retweeted
Advancing Mass Spectrometry@AdvancingMass8 Mar 2023
AMS 2023 conference will be held in Austin at the University of Texas from July 23-26, 2023. Mark your calendars! For additional details, including session topics and confirmed speakers, visit advancingms.org/

Advancing Mass Spectrometry

Advancing Mass Spectrometry for Biophysics and Structural Biology

advancingms.org
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Please RT. Online registration is still open for the Summer School on Computational Tools for Structural Interpretation of Ion Mobility Spectra chem.fsu.edu/ims-summerschoo…. Please find the finalized program below. @asmsnews @ISIMSSociety @FemalesInMS
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Gas-Phase Unfolding of Protein Complexes Distinguishes Conformational Isomers @CNS_UMass @UMassAmherst #GasPhase #Unfolding #Protein #Conformational #Isomers pubs.acs.org/doi/10.1021/jac…

Gas-Phase Unfolding of Protein Complexes Distinguishes Conformational Isomers

Abstract. Proteins can adopt different conformational states that are important for their biological function and, in some cases, can be responsible for th

pubs.acs.org
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Hi, friends! We are currently seeking a new post-doctoral student! 🧪🥼 Find out more/apply here: asms-jobs.careerwebsite.com/… Additionally, please feel free to reach out to any of us for any and all questions you may have! Lab website: sites.lsa.umich.edu/ruotolo/
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I think I've said most of what I want to say here, so I'll just post it and let others take the mic pubs.acs.org/doi/full/10.102…
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A post-doc position in my group in Manchester on HDX-MS of membrane proteins. Please get in touch for more details: jobs.manchester.ac.uk/displa…

Research Associate in HDX Mass Spectrometry of Membrane Proteins :Oxford Road, Manchester

jobs.manchester.ac.uk
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Boldly announcing our existence with this new sign! Join us and increase our atomic mass. We are well funded and looking to hire a postdoc to work on uncovering the mechanisms of how the innate immune system activates adaptive immunity. Experience with mice is preferred. RT!!
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The moment we've all been waiting for... 🧪⚡️The #JBCMethodsMadness Championship💥🏆 FINAL ROUND: #TeamMassSpec vs. #TeamCryo Which method should be crowned champion?
33%Mass Spectrometry
67%Cryo-EM/ET
5,572 votes • Final results
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Happy Monday! Voting starts now! ROUND 1: #TeamMassSpec vs. #TeamNMR Who should advance to the next round? Let us know in the comments and retweet to help spread the word! #JBCMethodsMadness #MassSpec #NMR #Methods #OpenAccess
67%Mass Spec
33%NMR
1,251 votes • Final results
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We are continuing our collaboration with the @VachetLab. We have improved our algorithm to model protein structure from DEPC covalent labeling data. Now out in @J_ASMS pubs.acs.org/doi/10.1021/jas…

Accounting for Neighboring Residue Hydrophobicity in Diethylpyrocarbonate Labeling Mass Spectrome...

Abstract. Covalent labeling mass spectrometry allows for protein structure elucidation via covalent modification and identification of exposed residues. Di

pubs.acs.org
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If you'd like to contribute to this kind of work at the interface of mass spec and neuro, I have a postdoc position open. please retweet
Journal of Proteome Research@JProteomeRes26 Jan 2022
One of our current most read articles is from our latest issue. In it, researchers uncover hidden gems within data-independent acquisition proteomics for Alzheimer’s disease and highlight the utility to pilot studies. pubs.acs.org/doi/10.1021/acs…
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Meet a mentor: Monique Johnson, NIST research chemist #MentoringMonth
A woman smiles for a photo. Text reads: "National Mentor Month. Monique E. Johnson, Research Chemist. How long have you been a mentor or advisor? My first mentor opportunity was my first year in graduate school. I had no idea what I was doing and neither did my mentee, but the best part was the process and investment of figuring out the project together, day-by-day."

ALT A woman smiles for a photo. Text reads: "National Mentor Month. Monique E. Johnson, Research Chemist. How long have you been a mentor or advisor? My first mentor opportunity was my first year in graduate school. I had no idea what I was doing and neither did my mentee, but the best part was the process and investment of figuring out the project together, day-by-day."

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Epitope Mapping with Diethylpyrocarbonate Covalent Labeling-Mass Spectrometry #AC pubs.acs.org/doi/10.1021/acs…

Epitope Mapping with Diethylpyrocarbonate Covalent Labeling-Mass Spectrometry

Abstract. Antigen–antibody epitope mapping is essential for understanding binding mechanisms and developing new protein therapeutics. In this study, we inv

pubs.acs.org
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Distinguishing Histidine Tautomers in Proteins Using Covalent Labeling-Mass Spectrometry #AC pubs.acs.org/doi/10.1021/acs…
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The lab’s first ASMS abstract submitted yesterday and our first paper is out today! pubs.acs.org/doi/full/10.102…

Fragmentation and Mobility Separation of Peptide and Protein Ions in a Trapped-Ion Mobility Device

Abstract. Ion mobility separations (IMS) have increasingly been coupled with mass spectrometry to increase peak capacity and deconvolute complex mass spect

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