
UNITY is harnessing pathways of aging biology to develop new senolytic medicines, with a focus on retinal diseases | $UBX
San Francisco Bay Area, CA
Joined March 2016
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Today we announced complete 36 week results from the Phase 2b ASPIRE clinical trial of intravitreal UBX1325 in patients with diabetic macular edema #DME who had poor vision despite prior anti-VEGF treatment.
Read the full announcement: ir.unitybiotechnology.com/ne…
As the aging biology field evolves, we’re learning more about the role of cellular senescence in diseases. CEO @anirvan0419 discussed our approach as pioneers in the senolytics field and our recent Phase 2b ASPIRE trial results.
Read on @LongevityTech: longevity.technology/news/we…
We’ll be presenting first time results from the ASPIRE Phase 2b study of UBX1325 for #DME at #ARVO2025 this Wednesday, May 7.
@ArshadKhanani, M.D., M.A., FASRS will host the presentation onsite at 11:00 a.m. MDT.
More details: ir.unitybiotechnology.com/ne…
The Phase 2 BEHOLD study data results of UBX1325 in patients with diabetic macular edema (DME) were published in the @NEJMEvidence peer-reviewed journal.
Read the full announcement and access the article: ir.unitybiotechnology.com/ne…
Today we reported Q1 2025 financial results and provided forward-looking business updates as we anticipate full 36-week Phase 2b ASPIRE data in Q2.
See the earnings release: ir.unitybiotechnology.com/ne…
Our collaboration with Vestrum Health, @corevitasdata has been instrumental in driving efficiency and accelerating patient enrollment in our ASPIRE Phase 2b #DME study.
Hear from Sara Huang, SVP of Clinical Operations on the impact of this partnership below.
Data from our Ph 2b ASPIRE Study found that UBX1325 generally outperformed aflibercept in patients who had moderate DME disease severity, potentially addressing a treatment breakthrough for patients who have exhausted existing therapies.
Read more: bit.ly/3RjoS5R
Today we announced topline results from the Phase 2b ASPIRE clinical trial of intravitreal UBX1325 in patients with diabetic macular edema (#DME) who had poor vision despite prior anti-VEGF treatment.
Read the full announcement: ir.unitybiotechnology.com/ne…
Today, we welcomed Yehia Hashad, MD, to our board of directors. As an experienced ophthalmologist and pharmaceutical executive, he will help guide the continued execution of our strategic vision of UBX1325 in #DME ir.unitybiotechnology.com/ne…
Today we announced our Q4 and full year 2024 financial results and business updates, including progress on our senolytic pipeline and the upcoming 24-week topline data from our Phase 2b ASPIRE study in diabetic macular edema (#DME).
See the full release: ir.unitybiotechnology.com/ne…
To our dedicated staff—you are the heart of our company.
At UNITY, we foster an inclusive culture that celebrates individuality and embraces our rich diversity. We’re grateful to our wonderful team for continuously embodying the heart of UNITY! #EmployeeAppreciation
Where can #DME patients turn to after anti-VEGF treatment plateaus?
#UBX1325’s novel MOA shows promise for additional visual gains, even after anti-VEGF therapy. Hear from Dr. Dante Pieramici on how UNITY’s senolytic approach could redefine DME care.
bit.ly/3XpnuCP
Ever wonder what our executives’ lives are like outside of advancing our #DME senolytic candidate? Our CMO Federico Grossi, M.D., Ph.D. shared how he unwinds in his garage-turned-workshop in this week’s edition of @statnews' “Up and down the ladder” below. statnews.com/pharmalot/2025/…
We’re headed to #JPM25! Just a short drive from our South San Francisco office, we’re looking forward to gathering with new and familiar faces onsite.
On the ground and interested in connecting? Reach out here: bit.ly/3ZXlVgJ
We’re excited to welcome Federico Grossi, M.D., Ph.D. as our new chief medical officer. He brings a wealth of experience in clinical and regulatory strategy and will support the clinical development of our lead candidate UBX1325. $UBX ir.unitybiotechnology.com/ne…






