Cognitive phenotypes and neuropsychological trajectories in post-COVID-19 syndrome: a 12-month follow-up study 🚨LongC0VID brains: memory often rebounds within a year, but attention and processing speed stay stuck. New 12-month study of 92 patients shows selective recovery, not full return to baseline. The daily life consequences...... 👇😧 ➡️This again interesting Spanish 12-month longitudinal study followed 92 adults with post-COVID19 syndrome (PCS: mean age ~49 years, predominantly women) who had previously undergone comprehensive neuropsychological assessment, ➡️Participants were retested after roughly 1 year using the same battery covering attention/processing speed, memory, executive functions, visuospatial abilities, and language, ➡️Pre–post comparisons (Wilcoxon tests with FDR correction) showed significant gains mainly in verbal memory (learning and recall measures), visual memory, matrix reasoning, inhibitory control, and certain action-processing tasks (fluency and naming), ➡️In contrast, attention and processing-speed measures remained largely unchanged, ➡️Using a domain-based phenotype approach, the proportion of participants classified as having normal cognition increased (from 65.1 % to 77.1 % at the −1 SD cutoff and from 83.1 % to 86.7 % at the stricter cutoff), ➡️Residual impairment was predominantly single-domain and driven by attention/processing speed, ➡️Multi-domain profiles that persisted also frequently involved this domain, ➡️Exploratory analyses linked neither cognitive reserve nor affective symptoms strongly to trajectories, ➡️The sample characteristics note that 51 % reported COVID-19 reinfection and 90 % were vaccinated. The study does not analyse or report any specific effects of reinfection or vaccination status on cognitive trajectories, phenotypes, or recovery rates, ➡️Overall, the data indicate selective, partial cognitive recovery in PCS, with attention and processing speed emerging as the most persistent vulnerabilities. ‼️So, one year later, memory and some higher-level thinking skills improved in people with LongC0VID syndrome, yet attention and processing speed barely recovered, leaving a lasting vulnerability. In everyday terms: trouble focusing and thinking quickly can still make ordinary things harder, staying concentrated while driving in traffic, flying as a pilot, keeping up with a complicated conversation, meeting work deadlines, or using phones and computers without getting overwhelmed. Memory often gets better (so people may forget less), but the stubborn attention problems can leave them slower, more mentally drained, and make it tougher to fully get back to work or social life even when other thinking skills improve. Sound familiar??? #AvoidSars2 #AvoidReinfections nature.com/articles/s41598-0…