Professor of Pharmacology at Pitt. Investigator at the Vascular Medicine Institute. Interested in calcium signaling in physiology and disease.
Pennsylvania, USA
Joined February 2019
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Small Correction. Had to delete &retweet. In final form. Response to 3 attack papers by (now former) EiC+EBMs on the same issue of their own journal. If we were wrong, 1 peer-reviewed data-driven paper in an independent journal would have been enough.
doi.org/10.1093/function/zqa…
Trebak Lab retweeted
Check out our new paper. A great collaboration between the Yule, Orlandi and Groblewski labs:physoc.onlinelibrary.wiley.c…
Trebak Lab retweeted
Don’t miss this week’s new issue of #ScienceSignaling! New research shows how the loss of a calcium-sensing protein can exacerbate colorectal cancer growth, a preclinical study identifies dendritic scaffolds that shape the plasticity of synapses, and more. scim.ag/3FStmP1
Trebak Lab retweeted
Loss of the calcium sensor #STIM2, but not of STIM1, worsens #ColorectalCancer growth and metastasis by boosting calcium ion content in the endoplasmic reticulum, remodeling mitochondria, and rewiring transcriptional activity. @TrebakM @Trayambak_P scim.ag/44v3O3E
Great piece Manuel! Thank you!
🚨Editorial Alert🚨 Excited to share this editorial highlighting work from Magda Chrzanowska group in collab with @TrebakM Lab on the role of Rap1A in lung endothelium: ahajournals.org/doi/10.1161/…
Collab with @Miguel_MartinAB & @MNCline @UCDavisHealth
ahajournals.org/doi/10.1161/…
Trebak Lab retweeted
We're excited to share that @APSPhysiology named @mf_navedo the 2025 recipient of the Robert M. Berne Distinguished Lectureship! This award is presented annually by the society’s Cardiovascular Section to an established leader in cardiovascular research. ucdavis.health/3BEi7qJ
Trebak Lab retweeted
Paper alert!!! I am excited to share our recent work showing that phosphorylation of a single amino acid on the vascular Cav1.2 channel controls vascular reactivity & blood pressure in #hypertension. @ucdavis, @UCDavisHealth, @MCIPUCD, @UCDAVISPharmac1
ahajournals.org/doi/full/10.…
Check out our new study in collaboration with the Chrzanowska lab showing that Rap1A regulates CRAC channels in endothelial cells as a mean to control NFAT activation and vascular inflammation!
ahajournals.org/doi/pdf/10.1…
Congratulations on a fantastic lecture Martha!
Thank you to #ECS2024 for establishing the Claude Klee memorial lecture and inviting me to deliver this keynote. Great way to celebrate Claude Klee’s legacy and talk about calcineurin!
Trebak Lab retweeted
Check out our new offering. Great collaboration with Serysheva lab. @Irina52948708
biorxiv.org/content/10.1101/…
Trebak Lab retweeted
I hope labs in Africa will take advantage of this fantastic opportunity! 🔬🌍
📢GOOD NEWS!
The Africa Microscopy Initiative, in partnership with @zeiss_micro will distribute refurbished research-grade light microscopes to African Scientists.
Read more and APPLY: equipment.microscopy.africa/…
Deadline: 13 September 2024
Trebak Lab retweeted
This is going to be a great meeting for vascular folks. Don’t suffer FOMO and register today!
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Trebak Lab retweeted
Check out our new collaboration with @RoseEDixon1 from @ucd_physiology in @PNAS (pnas.org/doi/10.1073/pnas.23…). We observed two modalities of beat-to-beat ATP fluctuations in ventricular myocytes based on SR-mitochondrial coupling strength. (1/2)
Trebak Lab retweeted
Excited to announce the next #ECSwebinar on June 5th - 5 PM CET!🌟
We are looking forward to the talk of David Yule on modulation of IP3R regulation by Ca2+.
Find meeting link and updates on upcoming webinars here: docs.google.com/spreadsheets…
@DavidYule64
Trebak Lab retweeted
Great opportunity for a young assistant professor in a vibrant research environment at WCMQ and in Qatar to perform cutting edge cell biology research with translational potential. wcmq-academicpositions.odoo.…
Trebak Lab retweeted
Check out this large collaborative effort re computational approach to drug design nature.com/articles/s41598-0…
Congrats to @lfsantana68 for being named Distinguished Professor at UC-Davis, apparently the first Latino to receive this honor. Well deserved Fernando!
Trebak Lab retweeted
Inflammation is a common feature of many diseases.
Murali Prakriya, PhD, discusses the evolution of this groundbreaking research in ion channels and his latest findings, which were published in @NatureComms, in this episode of our #BreakthroughsPodcast.
spr.ly/6018kJdyC
Trebak Lab retweeted
Contact sites between organelles are critical for cell physiology. Interestingly during cell division the contacts between the ER and mitochondria expand with implications on cellular energetics. cell.com/iscience/fulltext/S…
