Professor and Founding Head of Center for Translational Cardiology and Pragmatic Randomized Trials (@CTCPR_). Cardiac imaging, heart failure and RCT’s.
København, Danmark
Joined June 2020
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Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
Llega uno de los momentos más esperados de la jornada de hoy: la conferencia inaugural de #AEVigo26.
El Professor @TorBiering es el encargado de impartirla para hablar sobre ciencia de datos, vacunación personalizada y adultos de alto riesgo.
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
¿Cómo podemos evaluar mejor la eficacia de las vacunas en el mundo real?
👉 Combinar los registros nacionales con ensayos clínicos aleatorizados permite obtener evidencia sobre cómo funcionan las vacunas, su capacidad para prevenir hospitalizaciones y su coste-efectividad.
🎥 Tor Biering-Sørensen @TorBiering , profesor, médico jefe y ponente inaugural del XIII Congreso de la AEV, explica este enfoque innovador y cómo puede ayudar a decidir qué vacunas implementar en salud pública.
#AEVigo26
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
🙌 ¡Hoy comienza el XIII Congreso de @AEV_Vacunas!
Por la mañana, seguimos con los simposios del precongreso. Por la tarde, @TorBiering abrirá las sesiones científicas con una conferencia sobre vacunación personalizada. Después, hablaremos de sarampión y celebraremos la inauguración oficial, antes de dar paso a las comunicaciones orales.
📣 ¡Os esperamos en #AEVigo26!
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
Denmark strongly disagrees with US decision to impose sanctions on the ICC, which will have immense consequences for the work of the court and the investigation of the most serious international crimes. DK reaffirms its unwavering support to the @IntlCrimCourt.
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
🫀How does inflammation during influenza affect cardiac function?
The FluHeart Study, led by @KristofferSkaar with colleagues from @CTCPR_ examined 241 patients hospitalized with laboratory-confirmed influenza.
54% had LV dysfunction, while higher CRP levels were independently associated with elevated LV filling pressure, pulmonary hypertension and RV dysfunction.
The findings highlight a potential link between influenza-related inflammation and cardiac impairment.
Read the full study here:
onlinelibrary.wiley.com/doi/…
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Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
❤️ Can age- and sex-specific reference ranges improve LV strain rate assessment?
A recent Copenhagen City Heart Study led by @JacobChrDK and colleagues from @CTCPR_ included 1.930 healthy participants to establish age- and sex-specific reference values for LV strain rates.
Low global late diastolic strain rate (GSRa) was independently associated with higher risk of cardiovascular death, HF or acute MI — highlighting its potential prognostic value.
Read the full study here:
heart.bmj.com/content/early/…
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@matslassen
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Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
❤️How reliable are respiratory infection diagnoses in the Danish National Patient Registry?
A Danish study, published in the International Journal of Infectious Diseases, by Jacob Christensen and colleagues from @CTCPR_ examined 43 influenza/pneumonia hospitalizations among 12,477 participants in the DANFLU-1 trial.
The positive predictive value was 86–91% vs medical expert opinion, but 65–67% when requiring symptoms plus laboratory/radiological confirmation.
All 3 influenza diagnoses were confirmed, while uncertainty was mainly related to pneumonia.
The findings highlight the importance of validating registry-based outcomes when using nationwide health data for clinical research.
Read the full study here:
sciencedirect.com/science/ar…
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Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
🫁 Does chronic kidney disease affect RSV vaccine effectiveness?
A prespecified DAN-RSV analysis in European Journal of Preventive Cardiology, led by @LisaSteenDuus with @CTCPR_ colleagues, examined 131.276 adults ≥60 years, including 13.364 with CKD.
RSVpreF reduced RSV-related respiratory and cardiorespiratory hospitalizations, with no significant difference in vaccine effectiveness by CKD status
Read the full study here:
academic.oup.com/eurjpc/adva…
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@niklasdj1
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@AM_reimer
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@GuldasKose
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
❤️ How does GLP-1 treatment affect cardiac physiology?
A Danish study in European Journal of Heart Failure, led by Frederik Fussing and colleagues from @CTCPR_, examined HeartLogic sensor data from 666 ICD/CRT patients, including 111 initiating GLP-1RA treatment.
GLP-1RA initiation was associated with higher heart rate and thoracic impedance, and lower S1 amplitude. Semaglutide was used in 95% of initiators.
The findings highlight the potential of implantable cardiac devices and remote monitoring to capture physiological changes following GLP-1RA treatment.
Read the full study here:
academic.oup.com/eurjhf/arti…
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Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
#IDCBreathAndBeyond: Preventing respiratory infections means protecting #CardiovascularHealth ❤️ This #WorldHeartDay, we're highlighting the growing evidence showing a two-way link between respiratory virus infections & #CVD. Learn more: eswi.org/education-hub/idcbr… #DontMissABeat
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
🫁 Does diabetes affect RSV vaccine effectiveness?
A prespecified DAN-RSV analysis led by @MananPareekMD with @CTCPR_ colleagues, published in Diabetes Care, examined 131,276 adults ≥60 years, including 14,439 with diabetes.
RSVpreF vaccine effectiveness was consistent in people with and without diabetes — despite higher event rates among those with diabetes.
@TorBiering
@CopCard
@RigsHeart
@HGHHjerte
@Stenodiabetes
@matslassen
@niklasdj1
@KristofferSkaar
@AM_reimer
@dons_maria
@KBernholm
@fdavidovski_MD
@LisaSteenDuus
@camillaiottosen
@AnneBjergn
@drJBorchsenius
@Espersen_C
@GuldasKose
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
How can real-world data improve clinical trials?
A recent paper by @NinaNouhravesh and @CTCPR_ collaborators in Trials explores how RWD can support patient identification, safety assessment, and regulatory decision-making — while highlighting the need for better data quality, interoperability, and collaboration.
📖 Read the full paper here: link.springer.com/article/10…
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Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
New research from @AM_reimer and colleagues from @CTCPR_, published in @CIDJournal, shows that electronic nudges can increase influenza vaccination uptake among immunosuppressed adults.
Vaccination increased by 4.1 percentage points among immunosuppressed participants—and by 13.3 percentage points among younger adults with chronic conditions and immunosuppression.
An important example of how simple, low-cost interventions can improve vaccination uptake in high-risk populations. 💉
Read the article here:
academic.oup.com/cid/article…
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@LisaSteenDuus
@KiraJanstrup
Please see our results from the extended DAN-RSV trial in @NEJMEvidence 👇
In a randomized trial that included expanded enrollment during a second RSV season, the RSV prefusion F vaccine was associated with a lower incidence of RSV-related respiratory tract disease hospitalization as compared to no vaccine. Full trial results: eviden.cc/45IHPq3
ALT This image is a forest plot showing vaccine effectiveness for an RSVPreF vaccine across various subgroups. The subgroups include different age groups, years, countries (Denmark and Spain), health characteristics (such as chronic lung disease, cardiovascular disease, immunodeficiency), and vaccination history. Each subgroup lists control and vaccine participant numbers, followed by a graphical representation with confidence intervals. The plot visually compares control versus RSVPreF vaccine groups.
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
𝗢𝗿𝗶𝗴𝗶𝗻𝗮𝗹 𝗔𝗿𝘁𝗶𝗰𝗹𝗲𝘀
Durability of RSV Prefusion F Vaccine Protection across Two RSV Seasons eviden.cc/4ztWEdx
Bivalent RSV Prefusion F Vaccine to Prevent Hospitalizations in Adults eviden.cc/45IHPq3
Please see our results on the durability of the RSVpreF vaccine, new insights from the unique DAN-RSV trial
“Among adults 60 years of age or older, the [RSV prefusion F protein–based] vaccine was associated with a lower incidence of RSV-related respiratory tract disease during a second RSV season as compared to no vaccine.” Full trial results: eviden.cc/4ztWEdx
ALT This flowchart illustrates the process of a study on RSV vaccination from the 2024–2025 and 2025–2026 seasons. It starts with 131,379 participants. Of the 131,276 who underwent randomization, 65,642 were assigned to receive the RSVpreF vaccine, and 65,634 were assigned to receive no vaccine. Outcomes are documented for both periods. The chart details intention-to-treat analysis for each season.
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
🔴 ⏯️ Recording available: Focus on respiratory virus ↔️ NCD links at #WOHC2026. Co-organised by #ESWI. "Exploring bidirectional links between respiratory viruses & non-communicable diseases". Available: eswi.org/education-hub/recor…
Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
Recent research from Kaveh Hosseini and colleagues from @CTCPR_ , published in @AmJCardio, shows that influenza vaccination may provide important cardiovascular protection in patients with ischemic heart disease or heart failure.
Vaccination was associated with 28% lower all-cause mortality, 23% lower cardiovascular mortality, and 19% lower risk of MI.
An important reminder of the potential role of influenza vaccination in cardiovascular prevention. 💉🫀
Read the full article here:
sciencedirect.com/science/ar…
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Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
New research from Ramin Assempoor and colleagues from @CTCPR_ , published in Cardiovascular Diabetology, shows that higher C-reactive protein–triglyceride glucose index (CTI) is strongly associated with mortality among adults with MASLD.
Those in the highest CTI quartile had an 86% higher hazard of all-cause mortality and a 107% higher hazard of cardiovascular mortality.
An important step toward better risk stratification in MASLD—and further evidence of the link between inflammation, insulin resistance and cardiovascular risk. 🫀
Read the full article here:
link.springer.com/article/10…
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Tor Biering-Sørensen, MD, MSc, MPH, PhD retweeted
New research from @matslassen and colleagues from @CTCPR_ , published in @CircAHA , shows that poor cardiovascular–kidney–metabolic (CKM) health is widespread in older adults and strongly linked to heart failure risk.
Higher CKM stage was associated with worse cardiac remodeling—and up to an 8.3-fold higher risk of incident HF.
An important step toward better risk stratification and prevention. 🫀
Read the full article here: ahajournals.org/doi/10.1161/…
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