@TimCaseyClyde

Cell engineering. PhD @UCSF. Bay Area forever 🌉

 San Francisco, CA
Joined June 2019
  • Tweets403
  • Following867
  • Followers1.2K
103Media
My PhD work is now out at @elife! Special thanks to @LabRaleigh for making it all possible! doi.org/10.7554/eLife.100159…
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Congrats @sjohnliu !!
RaleighLab@LabRaleigh7 Oct 2024
New collaborative paper with @LukeGilbertSF showing the feasibility and value of in vivo functional genomics for understanding #glioblastoma. Congratulations to lead author @sjohnliu and all the other investigators! @NeurosurgUCSF @UCSFCancer @UCSF link.springer.com/article/10…

In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiother...

Genome Biology - Genetic perturbation screens with single-cell readouts have enabled rich phenotyping of gene function and regulatory networks. These approaches have been challenging in vivo,...

link.springer.com
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Stellar work from @Charlotttiie10 and @LabRaleigh !!
RaleighLab@LabRaleigh9 Sep 2024
How do "benign" meningiomas grow? And can we tell if they're benign using non-invasive tests? @Charlotttiie10 from @LabRaleigh answers both of these question in a collaboration with @dlswaney, now online in @NatureComms. @NeurosurgUCSF @UCSFCancer @UCSF. rdcu.be/dTqVb
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PhDONE !! Grateful to @LabRaleigh and @UCSFGradDiv.
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Open postdoc position in @LabRaleigh at @UCSF !!
RaleighLab@LabRaleigh29 Jul 2024
Replying to @LabRaleigh
@LabRaleigh at @NeurosurgUCSF is hiring a postdoc with expertise and interest in preclinical and organoid models of brain tumorigenesis! Please apply or RT! @UCSFCancer @UCSF nature.com/naturecareers/job…

UCSF Postdoctoral Scholar in Brain Tumor Research - San Francisco, California

Postdoctoral position integrating wet lab and organoid technologies with support from bioinformatic co-investigators to understand brain tumor biology

nature.com
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Paris Olympics watch out
Niko McCarty.
@NikoMcCarty16 Jul 2024
A green alga cell can swim 100 microns per second. Scientists put little baskets on a wheel. As algae became trapped, they pushed and spun the wheel around.
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Tim Casey-Clyde retweeted
John Liu, MD PhD@sjohnliu10 Jun 2024
We’re opening the lab and recruiting at all levels! Come work with us on functional genomics in brain tumors. liulab.ucsf.edu @NeurosurgUCSF @UCSFCancer
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Amazing craniofacial GRC in Spain. Inspiring and creative developmental biology is thriving! @CTB_at_UCSF @GordonConf @LabRaleigh
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Tim Casey-Clyde retweeted
Hugo Tejeda@NeuroTejeda15 May 2024
When your antibody sucks and what little signal is there is just buried in background
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gobble gobble 🔬🦃
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Tim Casey-Clyde retweeted
RaleighLab@LabRaleigh21 Mar 2024
Mouse computed tomography data (even the WT mouse data) is my new favorite type of data. @Bush_lab @TimCaseyClyde @NeurosurgUCSF @UCSFCancer @UCSF
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*bombastic side eye*
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My PhD work is out now!! Using mouse genetics and single cell, we show Eed, a PRC2 subunit seldom studied in the neural crest, is a potent regulator of craniofacial development. Collective effort from @LabRaleigh @Bush_lab @sjohnliu @VasuLabUCSF. biorxiv.org/content/10.1101/…

Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural...

The histone methyltransferase Polycomb repressive complex 2 (PRC2) is required for specification of the neural crest, and mis-regulation of the neural crest can cause severe congenital malformations....

biorxiv.org
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If you’re in the mud in your PhD program, don’t fret. Your project will come together exactly at a time that will surprise and delight you. Your last year will be filled with discoveries and I promise, the time you went through the mud will have all been worth it. ☀️ – at San Francisco, CA
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Absolutely amazing. Nothing cooler than the intersection of genetics, developmental biology, and evolution!
Itai Yanai
@ItaiYanai28 Feb 2024
How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. nature.com/articles/s41586-0… @BoXia7
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SF you spoil me – at San Francisco, CA
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Long week eh? – at San Francisco, CA
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Friday slicin’
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Two recent @UCSF-led studies on Schwann cell tumors! Featured on the front page of @NatureComms, @sjohnliu, @TimCaseyClyde, & @LabRaleigh’s findings show how schwannomas transition into an immune-enriched state in response to radiotherapy: nature.com/articles/s41467-0…
Illustration depicting tumors forming in Schwann cells, which normally make the myelin that protects nerves. Art by Ken Probst.

ALT Illustration depicting tumors forming in Schwann cells, which normally make the myelin that protects nerves. Art by Ken Probst.

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Amazing to see our work investigating epigenetic landscapes of schwannoma make the front page! Shoutout to illustrators at @NeurosurgUCSF. – at San Francisco, CA
Nature Communications@NatureComms25 Jan 2024
New featured image on our homepage! nature.com/ncomms/ 3 papers on schwannomas, tumors of the nervous system derived from Schwann cells @VasuLabUCSF @LabRaleigh @sjohnliu #CancerResearch @NatResCancer nature.com/articles/s41467-0… nature.com/articles/s41467-0… nature.com/articles/s41467-0…
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