@TianLab

Welcome to Dr. Rong Tian’s Lab of the Mitochondria and Metabolism Center at the University of Washington. Safe space for all metabolites!!!

 South Lake Union, Seattle
sites.uw.edu/mmcslu/laboratories/research-laboratories-tian-lab-2-2-2/
Joined October 2018
  • Tweets196
  • Following516
  • Followers957
33Media
Thinking about measuring FAO in cultured cells? Check out this story. Great work by Julia and the team! @TianLab
Julia Ritterhoff@JuliaRitterhoff29 Nov 2024
We've been busy this year... It's great to see this published! Using 13C-FA tracing in proliferating cells, we observe a robust incorporation into TCA intermediates, which is quiet different from Seahorse analysis. journals.physiology.org/doi/…

13C stable isotope tracing reveals distinct fatty acid oxidation pathways in proliferative versus...

The TCA cycle serves as a central hub to balance catabolic and anabolic needs of the cell, where carbon moieties can either contribute to oxidative metabolism or support biosynthetic reactions. This...

journals.physiology.org
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Happy to share our work on the development of S100A1ct, a peptide based therapy for the treatment of HF. Great collaborative effort! @DZHK_germany @uniklinik_hd ahajournals.org/doi/10.1161/…

S100A1ct: A Synthetic Peptide Derived From S100A1 Protein Improves Cardiac Performance and Survival...

BACKGROUND: The EF-hand Ca2+ sensor protein S100A1 has been identified as a molecular regulator and enhancer of cardiac performance. The ability of S100A1 to recognize and modulate the activity of...

ahajournals.org
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Bravo!!!
Arianne Caudal@arianneinthelab1 Jul 2024
I am grateful to be appointed into the AHA @BCVSearlyCareer Committee, starting my two-year term today. BCVS was the first conference I ever attended, so it’s both surreal and exciting to serve in this new role. Thank you for your support @emmcnally @Rongtian2 @Joseph_C_Wu!
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It’s great fun to work with Zolt @AranyLab on this! Human cardiac metabolism is wide open field, come on in!!!
The Arany lab@AranyLab25 Jul 2024
it's been a while since we posted... Here our recent review w/ @Rongtian2 on HUMAN cardiac metabolism in @Cell_Metabolism : deep dive going back 50+yrs - turned out to be >300 refs! Much is known, much MORE needs figured out... cell.com/cell-metabolism/pdf…
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Excited to share our latest paper in @CircAHA!! Congratulations to Dr. Walker and team👏👏👏 Fantastic work!! Check it out!!👇 @Rongtian2 @MitochondriaMe1 @UWAnesthPainMed
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In a new Review, @JuliaRitterhoff & @Rongtian2 discuss metabolic mechanisms in physiological and pathological cardiac hypertrophy and #heart failure: rdcu.be/dc5eb
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Serendipity took us on a fun journey to identify an unique role of liver in balancing BCAA and glucose metabolism. cell.com/cell-reports/fullte…

Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in...

Nishi et al. report that mice with impaired BCAA catabolism due to Ppm1k deficiency show reduced gluconeogenesis. Mechanistically, accumulated BCKAs inhibit liver MPC activity, resulting in reduced...

cell.com
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Thanks for visiting and sharing the truly inspiring work, Jon! @MitochondriaMe1 @WUSTLmed @WUSTLImmuno @UWAnesthPainMed
Jon Brestoff@BrestoffLab4 Apr 2023
Had an amazing time at Univ of WA Mitochondria and Metabolism Center @MitochondriaMe1 @uwsomwwami in @UWAnesthPainMed @UW to share our work on #mitochondria transfer. Special thanks to Matthew Walker twitterless and @Rongtian2 for hosting me. Really exciting work being done here!
A slice of Seattle and its many clouds

ALT A slice of Seattle and its many clouds

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Outstanding performance of our fellow Lee Bockus at ACC Heart Tank! Go Lee!!! @UWMedHeart @obtusediagnol @uwmnewsroom @UWCardiology @TianLab
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Today we bid farewell to two beloved members of our lab: @ChenHongye and Pat Arinno. We wish you all success in your next endeavor. You will be missed! @TianLab @Rongtian2
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The Tian Lab is pleased to announce that Dr. Dennis Wang, acting instructor of the lab, has been awarded the VA Career Development Award!! Congratulations, @DennisDWang !!👏👏👏 @TianLab @RongTian2 @MitochondriaMe1 @UWAnesthPainMed
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Happy Thanksgiving from our lab to yours!!🥳 @TianLab @Rongtian2 @MitochondriaMe1 – at Seattle, WA
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Best Saturday AM walk with friends and colleagues for a cause dear to my heart! Huge thanks to Toni and Bella for leading our team!!! @TianLab @BellaReichardt and faculty support @FMoussaviHarami @JD98119 @pmjboyle We are #3 fundraiser among @UWMedicine @UWAnesthPainMed @UWISCRM
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It is so cool to see our #SciArt featured this month on the @NatureCVR website!!! @Rongtian2 @TianLab @JamesBr70114556 @Bruce_Lab_UW #crosslink #proteomics #mitochondria 1/2
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Have a look at our latest paper about safety and tolerability of NR in HFrEF! Out now!👇 Congratulations to Dennis and team !!👏 @Rongtian2 @TianLab @MitochondriaMe1 – at Seattle, WA
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Congratulations to Dennis, and the amazing team!!!
F Moussavi-Harami, MD@FMoussaviHarami14 Sep 2022
New study led by former @uwashfellows and current @UWCardiology faculty Dr. Wang looking at NR as potential treatment in HF! @UWMedHeart @MitochondriaMe1 @TianLab @SophiaAirhartMD @Rongtian2 @UWAnesthPainMed @jaccjournals jacc.org/doi/10.1016/j.jacbt…

Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction:

jacc.org
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Our worlds collided in this all-hands-on-deck @TianLab and @BruceLab collaboration which defined my PhD thesis. The outcome is the first quantitative mito protein interactome comparing healthy and failing hearts, out today in @NatureCVR @Rongtian2 @JamesBr70114556 @UWBiochemistry
Nature Cardiovascular Research@NatureCVR9 Sep 2022
Research|@TianLab and @Bruce_Lab_UW labs compare the #mitochondria protein #interactome in healthy and #hypertrophic murine hearts, providing insights into the complex mitochondria remodeling in #heartfailure|#crosslink #proteomics 👉rdcu.be/cVhUL
https://www.nature.com/articles/s44161-022-00127-4

ALT https://www.nature.com/articles/s44161-022-00127-4

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Research|@TianLab and @Bruce_Lab_UW labs compare the #mitochondria protein #interactome in healthy and #hypertrophic murine hearts, providing insights into the complex mitochondria remodeling in #heartfailure|#crosslink #proteomics 👉rdcu.be/cVhUL
https://www.nature.com/articles/s44161-022-00127-4

ALT https://www.nature.com/articles/s44161-022-00127-4

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Check our latest paper about the mitochondrial interactome in the failing murine heart! Out now!👇 Huge congratulations to Dr. Arianne Caudal and team for the hard work!!👏 @Rongtian2 @arianneinthelab @TianLab @MitochondriaMe1 – at Seattle, WA
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News and Views by Akira Yoshii and @Rongtian2 on the recent study by @AranyLab deciphering the #metabolic remodeling of the human failing #hearts by multi-omics analyses @TianLab nature.com/articles/s44161-0… 👉rdcu.be/cUEwI
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