Norbert Weiss retweeted
Our paper on the mechanism of sensitisation of primary sensory neurons by DRG macrophages after nerve injury is out in @GLIA_Journal @WileyNeuro !
onlinelibrary.wiley.com/doi/…
Norbert Weiss retweeted
The final version of our @physiolrev editorial is published!
Ion channel dysfunction is a hallmark for many diseases. Since ion channels are key therapeutic targets, we anticipate that unraveling new aspects of their dysfunction holds a huge potential towards novel treatments.
Insightful Editorial on "Recent insights into channelopathies" by
Dr. Osama F. Harraz @UVMLarnerMed and Dr. Eric Delpire @vumchealth reflect on disruptions in ion channels, known as #channelopathies. ow.ly/M9Gp50Qi650
#CalciumChannels #IonChannels #PotassiumChannels
Norbert Weiss retweeted
A little rant about American universities, in the light on the recent Congressional testimony debacle:
Today I learned that Harvard President Claudine Gay seems to have published only 11 peer-reviewed journal papers in her entire academic career.
'So what?', you might ask.
Well, that's about the number you'd normally need to get hired as a first-year tenure-track assistant professor at a decent state university.
It's the number I published in the 12 months before I got tenure.
It's about the number that my more workaholic colleagues publish every year, decade after decade, throughout their careers.
And it's less than 1% as many papers as get published by outstanding researchers like behavior geneticist Nick Martin (with over 1,500 journal papers).
The situation at Harvard is not unusual. The leaders of academia are not typically leading academics, in the sense of highly productive researchers or widely respected teachers.
One might say they are career bureaucrats - but that would misunderstand their crucial ideological function.
The American people need to understand that in modern universities, both public and private, administrators function more like party political officers in communist Russian or Chinese universities. They are selected, throughour their careers, largely for their political commitments, and their willingness to enforce them. Like Cold War commissars, their allegiance is to the party, not to academia where they happen to work.
I mean 'party' quite literally: the Democratic party. Most American university administrators are loyal Democrats, and can't really imagine why anyone wouldn't be. Very few are Republicans or Libertarians.
And an increasing proportion of them are fully woke identitarian Leftists: they often launched their careers with a short series of papers on woke topics, using woke ideological frameworks, published in woke journals - before turning to the administrative track that offers much more political power to propagandize, indoctrinate, and control.
'So what?', you're might ask.
I've seen many calls for university administrators to enforce the rules of classical liberalism and free speech more fairly. This is like asking a Soviet-era commissar to abandon their Communist party allegiance, and to develop an entirely new identity and ethos grounded in an ideology that they have spent their entire career fighting.
It will not happen. Political animals do not change their spots.
University presidents who have prioritized amassing ideological power over producing academic research will not suddenly rediscover the merits of open inquiry.
They need to be fired, and replaced with academic leaders who are actually leading academics - rather than party political officers.
mindingthecampus.org/2022/12…
Norbert Weiss retweeted
Fun opportunity to write a Perspective for @jacionline on the role of peripheral sensory neurons in immunomodulation. #Neuroimmunology
Peripheral somatosensory neurons listen and orchestrate the immune response 👇
sciencedirect.com/science/ar…
Norbert Weiss retweeted
Check out our new review: Parkinson’s disease, epilepsy, and amyotrophic lateral sclerosis—emerging role of AMPA and kainate subtypes of ionotropic glutamate receptors. @MariaKarela3
frontiersin.org/articles/10.…
Norbert Weiss retweeted
Just out our new research paper! We identify PIEZO2-dependent rapid pain system in humans and mice. The work led jointly by @OtmaneBouchatta and @M_Brodzki in a close-knit joint effort of @saadsnagi and @SzczotLab groups. 🧵 1/10 👇doi.org/10.1101/2023.12.01.5…
Norbert Weiss retweeted
Happy to share a new article from my postdoc in @NCMlab out in @JPhysiol !!
In this work, we describe a role for the M-type potassium currents, conducted by KCNQ channels in the differential control of motoneuron subtype recruitment.
physoc.onlinelibrary.wiley.c…
Norbert Weiss retweeted
New preprint out from the Weir lab, check it out here
biorxiv.org/content/10.1101/…
Norbert Weiss retweeted
Research from Dr. Raj Khanna & team at the NYU Pain Research Center finds that a new compound reversed four types of chronic pain -- outperforming gabapentin without troublesome side effects -- by indirectly targeting calcium channels.
nyu.edu/about/news-publicati…
Norbert Weiss retweeted
NEW paper alert from @KhannaLabNYU @nyuniversity @NYUPainResCtr
A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain | PNAS pnas.org/doi/10.1073/pnas.23…
Especially proud of this one as it represents a 10+ year journey to get here.
Norbert Weiss retweeted
Final PRINT version of this paper from @KhannaLabNYU --> Neuropilin-1 is essential for vascular endothelial growth... : PAIN journals.lww.com/pain/abstra…
Norbert Weiss retweeted
Preprint Alert: Molecular and Cellular Context Influences SCN8A Variant Function. doi.org/10.1101/2023.11.11.5… #SCN8A #ionchannels #epilepsy
Norbert Weiss retweeted
Piezo channels in gastrointestinal disorders
@jclinicalinvest jci.org/articles/view/171955
Norbert Weiss retweeted
📜 Preprint alert! Our latest work on #ephys analyses of human DRG & hiPSC-derived sensory neurons is now online @biorxivpreprint Thanks to the incredible team that made this possible! We hope this will be a useful resource to #pain researchers
biorxiv.org/content/10.1101/…
Norbert Weiss retweeted
Great complementary work by Gabriel Stölting, Ute Scholl & colleagues on their mouse model harboring another gain-of-function CACNA1D variant, which reflects the more severe gating changes & clinical phenotype. Check it out! 🎉 #CACNA1D #science #TogetherStronger
Isradipine therapy in Cacna1dIle772Met/+ mice ameliorates primary aldosteronism and neurologic abnormalities: buff.ly/3FtHlqv
@ChariteBerlin
#Endocrinology #Neuroscience
Norbert Weiss retweeted
🤩🎉 Several years of work packed into one paper - check it out. Thanks to all collaborators and friends, it was my pleasure and I‘m looking forward to continue these great, productive and fun collaborations. #CACNA1D @CavX_PhD @uniinnsbruck
The human channel gating–modifying A749G CACNA1D (Cav1.3) variant induces a neurodevelopmental syndrome–like phenotype in mice: buff.ly/3QbJ7Bo
@OrtnerNadine @uniinnsbruck
#Neuroscience
Norbert Weiss retweeted
REVIEW Here our recent overview on “Voltage Gated Sodium Channels in genetic epilepsy”.
I hope you will find it useful !
onlinelibrary.wiley.com/doi/…
Norbert Weiss retweeted
New Micro report: Electrophysiological characterization of a Cav3.2 calcium channel missense variant associated with epilepsy and hearing loss molecularbrain.biomedcentral…
Norbert Weiss retweeted
So excited to finally share our work on one of the two first construct-valid mouse models of gating-modifying CACNA1D (Cav1.3) variants implicated in neurodevelopmental and endocrine dysfunction in @JCI_insight. insight.jci.org/articles/vie…
Norbert Weiss retweeted
All set for my lecture on Sep. 19 at the Czech Academy of Sciences - Institute of Organic Chemistry and Biochemistry
Lecture: Rajesh Khanna uochb.cz/en/event-calendar/2…

























