@TheSladeLab

Associate Professor, Biochemistry, VA Tech. Bacteria, host-pathogen, cancer. Former athlete, mediocre rock climber, still finding what fuels my fire. Views=mine

 Virginia Tech
thesladelab.com
Joined January 2013
  • Tweets1.9K
  • Following1.3K
  • Followers1.5K
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Excited to share this collaborative work led by Scott Verbridge's group of @BEAMvt . A big thanks to @scisignal for another great review process and a second cover! @vtbiochem VT story out tomorrow and BBC podcast soon. science.org/doi/10.1126/scis…
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In less than 2 weeks I will shut the doors to my lab for the last time and start an entirely new career. I am very thankful for my time at Virginia Tech and @vtbiochem where I received great support and had amazing colleagues. Is it scary leaving a tenured position? 🧵
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Some might say yes, but I believe you have to trust your gut and bet on yourself sometimes to truly be happy. I have learned many lessons as a professor and PI and I am eternally grateful for the effort of students and scientists from my lab.
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I am more excited than ever for this new opportunity for my family and I, which is bittersweet of course. Last, I have made great friends and started long lasting collaborations through this platform. As this is likely my last Tweet, I thank you all and wish everyone the best!
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Always having fun in the lab. Here are our songs of the day so far this week. The lab that rocks together, publishes together. #confucius
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And one more
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Daniel J. Slade retweeted
Philip Dunne@ProfPipDunne2 Oct 2023
RT please: We are looking for a Scientific Project Manager to join our team. The role is based on Belfast & ideal for someone who has both postdoctoral research experience and project management experience This will become a long term role for our group hrwebapp.qub.ac.uk/tlive_web…
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Constant reminder to myself as a PI at the bench
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Since I spend a significant amount of time at the keyboard, I needed a change. Upgraded my key caps to something a bit brighter and I love it 🤙🏼🏝️. The before and after
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Sometimes you need to unwind. Fortunately we have friends we amazing views in Blacksburg
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*with. And I am not paying for a blue check just to edit grammar. #sorrynotsorry
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I forgot to introduce the World to the new family and lab dog, Lord Haesten Cnut Slade, King of the Brittany’s and chief presider of the couch. And yes, he’s soft and awesome 😎 From 7-17 weeks
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It’s been a decade since I received this note from my favorite bench mate. Still rings true today. Scientists helping other scientists to pull themselves together.
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Happy to share our latest work: Fusobacterium are naturally competent through Type IV pili. Great, concise study led by @blake_e_sanders and others not on twitter. We discovered it, now you go figure out what to do with it. sciencedirect.com/science/ar…
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All of this stems back to the great Fusobacterium secretion system analysis paper by @HendersonLab and colleagues that show potential Type IV or Type II secretion system genes. So we followed it and found an entire Type IV competence system.
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Finally, I guess now is a good time to stop telling people that Fusobacterium only have Type V secretion. But it's still up for debate if they have other protein secretion systems we have trouble identifying.
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Just found out that my anaerobic bag replacement is on hold because two other orders from my University aren't paid, they won't give me any info on who made the order so I have no power here. And I can't tape my bag enough because it's likely pre century. How's your day?
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Nice work Aideen, Phillip, and all involved! There might be something to this stroma phenomenon...
Aideen Ryan@aideenryan110 May 2023
If you are interested in how stromal cells in tumors suppress T cells, take a look at our research paper just published online and lead by @HannahEgan21 @olivertreacy1 cell.com/cell-reports/fullte…

Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microe...

Egan et al. show that stromal cells in the tumor microenvironment have elevated levels of sialic acid expression and can suppress activated T cells. Targeting sialylation using two independent...

cell.com
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A great read with really impactful work from @jutraslab and colleagues. I have no doubt this research will help a large group of people in the near future! 🚀 vtx.vt.edu/articles/2023/05/…
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