natural product biosynthesis, enzymes & drug discovery @UniBasel
Basel (Switzerland)
Joined September 2019
- Tweets154
- Following366
- Followers1K
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TeufelLab retweeted
@BioCIS, beautiful work on viduamanide, a new cyclopeptide isolated from the recently described deadly mushroom Amanita vidua in the Journal of Natural Products @ACSPublications @CNRSchimie @InsermIDF @ScienceSorbonne @BeniddirM
Two new studies lead by Sven Sowa: We developed a bioinformatic tool for the rapid analysis of related biosynthetic gene clusters to streamline the discovery of novel natural product congeners and distinct tailoring enzymes
pubs.acs.org/doi/10.1021/acs…
pubs.acs.org/doi/10.1021/acs…
Check out our new study lead by Heiner Weddeling! We explored amide bond synthetases to bioengineer new-to-nature rubromycin polyketides including “Trojan horse” siderophore conjugates.
pubs.acs.org/doi/full/10.102…
New study in @JACS overturns the proposed Baeyer-Villiger Monooxygenase role of RslO9 in rishirilide biosynthesis. Instead, it uses a Hooker oxidation-like mechanism: substrate hydroxylation + alkyl migration. Led by Heiner Weddeling @unibas
pubs.acs.org/doi/10.1021/jac…
YUCCA enzymes are key for plant auxin biosynthesis – but Sina Rütschlin (@Unibas) discovered their surprising dual role: they also drive chlorophyll degradation, which may link leaf senescence to auxin homeostasis in plants! Great collab w/ Simone Moser onlinelibrary.wiley.com/doi/…
TeufelLab retweeted
We are organizing our second workshop in this June at Riga with four Invited Speakers, Yvain Nicolet, Robin Teufel, Joleen Masschelein and Florian Hubrich.
TeufelLab retweeted
We had a wonderful 3rd Japanese-German Symposium on the Biosynthesis of Natural Products in Bonn. Thank you all for the great talks and fruitful discussions! See you again at the next conference in Japan.
TeufelLab retweeted
Very happy that our work on understanding tropolone biosynthesis is now out in @mbiojournal Great work from the PhD of @AlasterMoffat and some excellent biochemistry from @TeufelLab #biosynthesis #Pseudomonas
journals.asm.org/doi/10.1128…
TeufelLab retweeted
Happy to share our latest publication on a #flavin #oxidase family and a tool to depict and simplify enzyme mining and selection by @DEggerichs et al
#biocatalysis #flavoprotein #enzymology #biotechnology
nature.com/articles/s42004-0…
TeufelLab retweeted
🙏 for the highlight! @ChemEurope
Our Pick of the Week, published #OpenAccess in @ChemBioChem by @MarcGBQ, @KaiSchuelke, @Stephan_Hammer and team at @unibielefeld:
"Efficient Transferase Engineering for SAM Analog Synthesis from Iodoalkanes"
ow.ly/m1te50Rinso
TeufelLab retweeted
New @biorxiv_micrbio preprint from our group: "Understanding the biosynthesis, metabolic regulation, and anti-phytopathogen activity of 3,7-dihydroxytropolone in Pseudomonas spp.” Great work from @TheRealAlimoff with some important biochemical data from @TeufelLab
Understanding the biosynthesis, metabolic regulation, and anti-phytopathogen activity of 3,7-dihydroxytropolone in Pseudomonas spp. biorxiv.org/cgi/content/shor… #biorxiv_micrbio
TeufelLab retweeted
Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry.
Organic chemistry meets #DirectedEvolution
Highly interdisciplinary & passionate research group
🙏RETWEET (We want to recruit internationally)
uni-bielefeld.hr4you.org/job…
TeufelLab retweeted
We have set up a new Masters degree program, the MSc Physics of Life, at the Biozentrum in Basel. I am looking forward to training the next gen avant-garde at the interface of physics, maths, engineering and biology!
👉Scholarships available👈
NEW: MSc in Physics of Life – training in cutting-edge research at the interface of physics, mathematics, engineering and life sciences. Apply now and be one of the first students of the program. Scholarships available. @biozentrum @UniBasel_en ow.ly/r6h950QKBTX
TeufelLab retweeted
The Berg Lab is hiring two postdocs for the @ERC_Research funded Synergy project “Archean Park” (duration 3 years). #biochemistry, #microbiology
Link to application: tinyurl.com/arnmw9p3
Please RT!
I have one open Postdoc position (100%, natural product biosynthesis, protein biochemistry) & one PhD position (100%, natural products against glioblastoma brain cancer). Join our lab with great colleagues and salaries located in vibrant Basel. Please RT!
jobs.unibas.ch/?lang=en
I have an open 100% postdoc position (natural products & mass spectrometry / ms networking). Come and work with us in fantastic Basel with great colleagues / salary and a vibrant pharma community ;). Please RT!
jobs.unibas.ch/offene-stelle…