@Tate_Lab

The Viral Immunity and Immunopathology Laboratory at @Hudson_Research @CiiiD_Research Host-directed therapies for #influenza and pulmonary inflammation

 Melbourne, Australia
hudson.org.au/research-group/viral-immunity-immunopathology/
Joined March 2023
  • Tweets45
  • Following129
  • Followers109
🫁 It’s the epithelium, not myeloid cells. Epithelial NLRP3 drives lung injury and fibrosis via IL‑18 and pro‑fibrotic neutrophils. doi.org/10.1186/s12989-026-0…

Epithelial NLRP3 drives silica-induced lung injury and fibrosis through IL-18 and pro-fibrotic...

Particle and Fibre Toxicology - Silicosis is a progressive inflammatory and fibrotic lung disease with no effective treatments beyond symptom management. While global NLRP3 inflammasome deficiency...

link.springer.com
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Tate_Lab retweeted
NHMRC
@nhmrcApr 29
Although there are no effective drugs for severe influenza, a breakthrough led by @Tate_Lab in collaboration with Associate Professor Ashley Mansell, led to innovative treatments that target the body rather than the virus itself to limit inflammation and save lives. Read more in NHMRC’s 10 of the Best 17th Edition now on our website: ow.ly/yTS850YJiFC
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Excited to share our new work in @MucosalImmunol on preventing the #1 killer after flu: secondary bacterial pneumonia mucosalimmunology.org/articl…

Short-course intranasal LAT9997 therapy limits post-influenza bacterial pneumonia by recalibrating...

Influenza A virus (IAV) infection remains a major global health threat, not only due to its direct impact but also its role in predisposing the respiratory tract to secondary bacterial infections.1...

mucosalimmunology.org
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Our latest paper on influenza and gasdermin E @CiiiD_Hudson @Hudson_Research nature.com/articles/s41419-0…

Gasdermin E deficiency limits inflammation and lung damage during influenza virus infection

Cell Death & Disease - Gasdermin E deficiency limits inflammation and lung damage during influenza virus infection

nature.com
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Exciting news! The AVS12 Meeting Report is now published in the @ASMicrobiology Journal of Virology 🎉 AVS prides itself on supporting all voices in virology through career development, Indigenous engagement, collaboration, and recognition of excellence. journals.asm.org/doi/10.1128…

Twelfth scientific biennial meeting of the Australasian Virology Society: AVS12 2024 | Journal of...

The Australasian Virology Society (AVS) biennial meeting is highly recognized as the premier virology conference in Australasia, fostering collaboration across diverse fields of virology and promot...

journals.asm.org
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🚨 Registrations for #AVS12 are still open! 🚨 📅 Dec 2-5 | 📍 RACV Goldfields, Creswick, VIC Join us for an unforgettable event! 🔗 Register now: avs2024.org
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Taking AIM at Influenza: The Role of the AIM2 Inflammasome ✍️by Xu & Tate 👉mdpi.com/1999-4915/16/10/153… #influenza #sensing #immunology
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Options for the control of influenza XII Conference #optionsxii2024 Brisbane
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Join us this December for AVS2024! Early Bird Registration & Abstract deadline is Friday 9th August Stay Posted here: avs2024.org
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When patients with severe flu are admitted to hospital there are no effective drugs available to reduce the response to the virus. Our researchers are focusing on finding treatments to help these patients 2024 flu season guide: bit.ly/4dWolB5 @Tate_Lab @CiiiD_Research
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Tate_Lab retweeted
Maggie@mlam24_28 Mar 2024
Thrilled to be receiving this award! Massive thanks to the @Lungfoundation and @Tate_Lab for all the support! #TSANZRS2024
Lung Foundation Australia@Lungfoundation27 Mar 2024
Lung Foundation Australia's Hope Research Fund grants for 2024 have been awarded! We would like to offer our congratulations to the early and mid-career PHDs and fellowships awardees 👏
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Lung Foundation Australia's Hope Research Fund grants for 2024 have been awarded! We would like to offer our congratulations to the early and mid-career PHDs and fellowships awardees 👏
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We are pleased to announce our April #ACDS Seminar will feature @Sarah_Rosli_ @Hudson_Research & Dr Robson Kriiger Loterio @BurnetInstitute! 👏 Join us on Wed 3rd April (11am AEDT on Zoom) to hear how GSDME alters #influenza severity 🫁 and how Coxiella stops host #celldeath! 🦠
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Save the date for AVS 2024 2nd– 5th December RACV Goldfields, Creswick, VIC Stay Posted here: avs2024.org/
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Congratulations to @DrEmilyGulliver from @Forster_Lab on winning best ECR talk and @Sarah_Rosli_ from @Tate_Lab for winning best student poster at #lorneiandi! What a great meeting which showcased so much of the exciting research ongoing here at CiiiD & @Hudson_Research ! 👏
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Our latest study is online - a novel host-directed therapy for influenza. @CiiiD_Hudson @Hudson_Research academic.oup.com/jid/article…

Harnessing Endogenous Peptide Compounds as Potential Therapeutics for Severe Influenza

AbstractBackground. Excessive pulmonary inflammation and damage are characteristic features of severe influenza virus infections. LAT8881 is a synthetic 16

academic.oup.com
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hudson.org.au/news/controlli…
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A/Prof Michelle Tate, PhD student Sarah Rosli & their team have identified a protein, Gasdermin D, in lung epithelial cells which promotes hyper-inflammation & cell death in severe cases of #Influenza. 🫁 Read more: bit.ly/3uRQXZY
L-R, A/Prof Michelle Tate and PhD student Sarah Rosli

ALT L-R, A/Prof Michelle Tate and PhD student Sarah Rosli

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Congratulations @kristian_barry7! Hendra virus C-protein activates the NLRP3 inflammasome. @CiiiD_Hudson @Hudson_Research doi.org/10.1186/s12950-023-0…
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Our latest paper is out today!Congratulations @Sarah_Rosli_ @CiiiD_Hudson @Hudson_Research doi.org/10.1038/s41419-023-0…

Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection

Cell Death & Disease - Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection

nature.com
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