Assistant Professor, Department of Cell and Biological Systems, Penn State College of Medicine. Researcher in #Tcell biology, #cancer and #immunity #biophysics.
Penn State College of Medicine
Joined May 2011
- Tweets3.4K
- Following598
- Followers578
- Likes8K
Pinned Tweet
Honored and humbled with the fact our works were featured three times by various journals since 2021. 1. pubs.acs.org/doi/10.1021/acs……
2. onlinelibrary.wiley.com/doi/……
3. science.org/doi/10.1126/scia…
Erdem Tabdanov retweeted
Çoook ilginç bir yayın okudum…
Editörü ikna etme sanatı! 😂
Yıllarca deney laboratuvarda deney yap, cihazların başında sabahla, binlerce veri topla, makaleyi yaz, istatisktik kabiliyetini göster, düzenle…
Sonra makaleni heyecanla editöre gönder ve hayatının en uzun bekleyişine başla!
-“Your manuscript is under consideration.”
Bu cümleyi görünce umutlanırsın…
-“Under review.”
Artık hakemlerin insafındasın…
-“Minor/Major revision.”
Hakemi cevapların ile ikna/mutlu etmeye çalışırsın.
Dr. Hites, 2021 yılında Science of the Total Environment dergisinde yayımlanan makalesinde bu süreci anlatıyor:
“How to convince an editor to accept your paper quickly”
Yani: “Editörü makaleni hızlıca kabul etmeye nasıl ikna edersin?”
Okumanızı öneririm, çok ilginç önerileri var
Erdem Tabdanov retweeted
Another high profile paper showing the formation of blebbisomes from another cell type and not even a citation of the blebbisome paper...... Really???? My talk at AAEV next month is going to be fun for me........... aaev.org/
Erdem Tabdanov retweeted
1. CRISPR came from basic research on bacteria.
2. Optogenetics started with a discovery in algae.
3. The GFP protein comes from jellyfish.
The biggest breakthroughs all trace to scientists follow their curiosity. This is one huge reason why we must keep funding basic research!
Erdem Tabdanov retweeted
Why should we kill senescent cells in cancer patients?
Senescent cells block T cells from killing the cancer.
Nature paper !
nature.com/articles/ncomms11…
Erdem Tabdanov retweeted
A real professor makes a simple problem look complicated, just to impress the students.😄
Erdem Tabdanov retweeted
🚨 New work from our lab:
ESR1 fusions don’t just alter ER signalling — they fundamentally change how the protein behaves in the nucleus.
We show they form chromatin-linked condensates that reshape nuclear organisation and transcription.
biorxiv.org/content/10.64898…
“Dumb ways to die, so many dumb ways to die…..”
Erdem Tabdanov retweeted
Thank you to the folks @NikonSmallWorld and this year's panel of judges for selecting my videos for the 2026 Nikon Small World in Motion competition! Have a look at all the winning videos at the link below.
Presenting... 🥁 ... The 2026 Nikon Small World in Motion winners! Congratulations to all of our winners, and thank you again to everyone who entered! The full gallery is available to view now:
nikonsmallworld.com/gallerie…!
Erdem Tabdanov retweeted
wake up babe new horrors beyond comprehension just dropped
An extraordinary @Nature paper has just landed from the lab of @Sergiu_P_Pasca at @Stanford - led by Konstantin Kaganovsky. They have found a way to create "xenocortical mice" which have ~92% of their cortex occupied by a cortical organoid derived from human stem cells. This human-derived cortical graft integrates deeply with the host nervous system, supporting organised neural activity and behaviour.
This study is a milestone in synthetic biology and chimera research. It has the potential to generate multiple medical breakthroughs by providing an enhanced biological model of human brain tissue that allows behavioural as well as neural and genetic assays.
The Stanford team have been exceptionally thorough and proactive in addressing ethical concerns that comes from this frontier work. But their pioneering work nonetheless raises many open questions: are the xenocortical mice conscious? Do they have any human-like properties of consciousness or cognition?
@NitaFarahany and I will be addressing some of these questions in a forthcoming commentary - where we'll also offer an ethically-informed roadmap to guide this important research as it progresses. In this context, "pacing the frontier" really does make sense 😉
Read the Stanford @nature paper here, and buckle up. It's wild. nature.com/articles/s41586-0…
Erdem Tabdanov retweeted
In an extraordinary new paper, just out, in Nature @Sergiu_P_Pasca and his team genetically altered mice to make them "apallial" (missing a cortex). And then, postnatally, transferred organoids derived from human neural cells into that space.
Three months later, in the animals measured, the cortex was 91.9% human-derived neural cells by volume.
The result is not quite a mouse mouse (albeit I would still say, it's a mouse!), and certainly not anything like a human. Nothing the researchers measured suggests these animals have human-like experiences.
What a model like this promises for neurological disease modeling and drug discovery cannot be overstated. It's nothing short of an extraordinary breakthrough.
It also raises complex ethical questions (to be clear, these researchers carefully engaged external ethicists (I was one of them), and followed every ethical and legal guideline possible.) Which is why In a forthcoming commentary, Anil Seth and I explore what an ethical roadmap forward would be for this work. We address whether these mice chimeras could have any human-like capacities, how we might measure and know, and who, and how, we decide together what the next steps in this research should be.
Erdem Tabdanov retweeted
Nature has just published a pretty incredible paper.
The authors introduce a framework that turns research papers into interactive AI agents.
Rather than engaging with a paper only as static text, researchers can question its agent, ask it to reproduce an analysis, or apply the paper’s methods to new data.
This could make research methods much easier to understand, reproduce, and use.
It also opens up a strange possibility: research papers that can, in a sense, talk to one another. The authors demonstrate this by connecting agents derived from different papers so that they can combine their methods and data.
Used carefully (and with human scientific judgment still firmly in the loop) this could become a powerful new form of scientific communication.
*
Full paper in the first reply
Erdem Tabdanov retweeted
New ad by the Norwegian Consumer Council about the declining lifespan of products.
Erdem Tabdanov retweeted
AI's energy problem is now so severe that companies are restarting decommissioned nuclear plants just to power GPU clusters. Your brain runs everything you think on 20 watts. A single LLM training run consumes what a small city uses in a year. So a few researchers stopped trying to build better chips and started growing them instead.
Cortical Labs built CL1 – 200,000 human neurons grown from skin cells, spread across electrodes, trained to play Doom. Not by programming, by punishment: chaos signal when they fail, calm when they succeed. The cells aren't playing to win. They're trying to make the noise stop. Final Spark now rents human mini-brains over the internet – same pitch, same logic, up to a million times less power than silicon.
12 minutes. Bookmark & watch today. The most uncomfortable thing happening in AI infrastructure right now.
