Assistant Professor at UT Southwestern Medical Center studying how glial cells sculpt the nervous system. Views are my own.
Dallas, TX
Joined September 2019
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Excited to introduce four new mouse lines described in our recent study @YiheZhang97 (soon available from JAX), including two lines for studying TFEB in broader contexts (TFEB 6xMyc, JAX#041044; Rosa26-TFEBS141A;S210A-Halo, JAX#041043) and two new KI lines for myelinating OLs.
Lu Sun retweeted
The most important briefings of the day.
Karl Deisseroth, professor of bioengineering and of psychiatry and behavioral sciences, shares the news of his Nobel Prize with his kids.
Lu Sun retweeted
This study identifies #oligodendrocytes as active contributors to #cognitive decline in #aging, by leveraging a unique #human brain bank with >70 years of associated cognitive data combined with experimental modeling of oligodendrocyte dysfunction. #Glia
nature.com/articles/s41591-0…
Lu Sun retweeted
Thank you Lu Sun, Ph.D. for presenting his talk, "Cellular and Molecular Mechanisms Governing Neuron-Glial Interactions" at the recent Klingenstein Fellowship Awards in Neuroscience Conference. @SunLab19
Lu Sun retweeted
"Find Your Way" - Olson strikes inspiring chords in musical keynote at Graduate School commencement - Center Times Plus, UT Southwestern utsouthwestern.edu/ctplus/st… via @@utswnews
Excited to share our recent PNAS paper (led by @Dani_B1256): pnas.org/doi/10.1073/pnas.25…, where we discovered the mechanisms governing myelin integrity during the onset of myelination. We are grateful to collaborate with Ellisman lab (UCSD), @WertLaboratory, and UTSW EM Core (1/6).
These defects are accompanied by prolonged visual signal transduction. We speculate that this mechanism that safeguards myelin integrity during early development might also play roles in myelin breakdown during neurodegeneration, where dysmyelination is a hallmark.
This work was supported by UTSW Endowed Scholar Funds @UTSWMedCenter, @utsweye, @UTSWBrain, @NatEyeInstitute, @klingensteinorg, @czi.
Lu Sun retweeted
The 2026 Klingenstein Fellowship Awards in Neuroscience Conference brought together current and past fellows, distinguished advisors, and colleagues for top-notch science, engaging discussions, slide and poster presentations, and community-building.
Today we say goodbye to @ZhangTingxin, an outstanding postdoc and research scientist in our group, as he begins his independent lab at SUSTech (the first one from our lab!). He published our group’s first paper and has another under review. Congratulations and best of luck!!
Lu Sun retweeted
OBI Investigator, Lu Sun, Ph.D. (right), & Aksheev Bhambri, Ph.D., developed a new research tool that sheds light on myelination. Learn how the discovery is providing deeper understanding of how neurological disorders like multiple sclerosis develop. bit.ly/49PPmEZ
Glad to share our published version: “ Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms”, led by @AksheevB
nature.com/articles/s41593-0…
We made the Enpp6-CreERT2 mice available from Jax: jax.org/strain/041040
and updated the premyelinating oligodendrocyte multiomic website: utswbioinformatics.shinyapps…
Lu Sun retweeted
A terrific new opportunity for new or early career faculty to join the outstanding and rapidly growing faculty of @UTSWBrain. Spread the word!
Lu Sun retweeted
Thanks to everyone for an amazing Myo Life celebration of the 40-year anniversary of the Olson Lab, along with a big birthday. Here's my special song for the occasion, "The Ballad of Myo Life". Rock on! 😎 @UTSWMedCenter
