@StraubLab

The Straub Lab studies redox-controlled cell signaling that regulates endothelial and smooth muscle biology of the microcirculation in physiology & disease.

 Pittsburgh, PA
straublab.pitt.edu/
Joined January 2025
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3Media
Our lab has identified differences in sickle cell treatment outcomes in individuals with a genetic variant in CYB5R3. Check out the full story here... ashpublications.org/bloodadv…

CYB5R3 T117S tempers fetal hemoglobin induction by hydroxyurea in patients with sickle cell disease

TO THE EDITOR:

ashpublications.org
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Check out a new publication coming from our lab showing new insights into barrier function in pulmonary fibrosis... insight.jci.org/articles/vie…
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Congrats to the newest PhD to graduate from our lab! Wishing Dr. Hall all the best as he moves on to advance his science career at the NIH!
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The Department of Pharmacology & Chemical Biology here at the University of Pittsburgh is ranked 4th in the nation for NIH funding with our lab ranking in the top 4% of all Pharm Investigators brimr.org/brimr-rankings-of-… Check out the important research here! pharmacology.us/
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Have a hard time overexpressing proteins in endothelial cells? Our lab has figured out why and a simple technique to overcome it! Read about it here... pubmed.ncbi.nlm.nih.gov/3899…

STING inhibition enables efficient plasmid-based gene expression in primary vascular cells: A...

Plasmid transfection in cells is widely employed to express exogenous proteins, offering valuable mechanistic insight into their function(s). However, plasmid transfection efficiency in primary...

pubmed.ncbi.nlm.nih.gov
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Listen to Dr. Straub's thoughts on a new possible therapeutic for Sickle Cell Disease pittmed.pitt.edu/news/sickle…
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What exactly do we do in our lab? Here are some basics!
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