Research group at UQ studying the integrated physiology of health and disease. Strong focus on motor neuron disease.
Brisbane, Queensland
Joined May 2019
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Enjoying several expert talks by key metabolism researchers, including the talented @SezSaysScience as part of the @UQMedicine supported Mini-symposium on #metabolism.
Enjoying quiet time in the lab as @melkg97 @StephanieHowe98 and @AmberGreen67157 take on the challenge of not speaking for 48hrs to support those who have lost their voices to #ALS #MND. Click below to support a worthy cause👇@MNDFoundation @UQMedicine
secure.mndandme.com.au/my-fu…?
Steyn_Lab retweeted
We will be extending abstract submission until CoB Tuesday 26th September for those of you running a bit tight to the deadline!
somersetevents.eventsair.com…
Last chance - 2 days to go - get your abstracts in!
Closes 21st September
Abstract submission for the 2023 Australia and New Zealand MND Research Symposium is open. Sage Hotel in Wollongong on Friday 17th and Saturday 18th November 2023. - mndaustralia.org.au/research…
In, this #OpenAccess manuscript by the talented EMCR @StephanieHowe98 et al., we explored associations between #Ghrelinand #LEAP2 (endocrine factors and regulators of #appetite) in ALS; findings were somewhat unexpected. A thread to help explain (1 of 5) doi.org/10.1111/ene.16052
5/5 - #ghrelin acts on the #hypothalamus 🧠to regulate #hunger 🍔 #metabolism 🔥; can we strengthen this to benefit #PALS. Thank you to @MND_RIA @UQMedicine, and @FightMND and @NIHfor supporting @NgoShyuan @ZigmanLab. A BIG thank you to the #PALS for their time and contributions
3/5 – When comparing findings with functional decline, lower #ghrelin and greater #LEAP2ghrelin was associated with lower physical capacity; #ghrelin does more than regulate appetite. It can be neuroprotective 🧠 and support muscle 💪 function. Are these benefits lost in #ALS?
2/5 - Seeking to improve understanding of why some #PALS lose appetite, we show that postprandial hunger hormone #ghrelin is lower in ALS, and a big increase in #LEAP2ghrelin, suggesting #LEAP2 might block #ghrelin actions. @ZigmanLab was instrumental in making sense of this.
Steyn_Lab retweeted
Abstracts are open for the Aus/NZ #MND Research Symposium 2023 in beautiful Wollongong 17-18 November. Talks will be selected from abstracts, lots of options available for #EMCRs @mndaustralia
@FightMND @MNDNSW @UOW @wollongong_nsw
Pls RT mndaustralia.org.au/research…
Steyn_Lab retweeted
A quick snapshot of our lab at @GRIDD_GU @GU_Sciences! 😎
Dont forget we have 2 positions to join our group!
*Postdoc lnkd.in/e_U35C88
*RA lnkd.in/eDr3N_Hy#
#zebrafish, #DiseaseModels, #Neurodegeneration, #MND, #drugdiscovery, #genetics, #schizophrenia, #microscopy
Steyn_Lab retweeted
Hi Network, we are recruiting!!!!
Research Fellow and Research Assistant.
If you want to be part of a dynamic team who plays with genetics, develops cell/zebrafish models of human diseases and conducts drug discovery campaigns! You should have a look 👇 1/3
Please share 🙏
Steyn_Lab retweeted
Our Scientific Seminar Series is back with a new time on Tues, Feb 28 at 12pm AEDT! Our first talk is @Fred_Steyn & @HoldomCory from @Steyn_Lab with 'Use and validation of digital technologies, including actigraphy, for care and research in MND.' For more fal.cn/3vUfr
Collaborative project between @UQ_News and @UMCUtrecht showing that wear location will impact #actigraphy outcomes in #ALS #MND
Led by #PhD student @HoldomCory with insights from @rpavaneijk. Thank you for support from @HondaFoundation
@WesleyResearch @MNDFoundation @FightMND
I'm excited to share our paper following from @rpavaneijk's work on the use of passive actigraphy for monitoring #ALS #MND function outside the clinic. There is clearly a lot of opportunity to expand the potential of this technology. @Steyn_Lab @Ngo_Lab:
doi.org/10.1007/s00415-023-1…
Steyn_Lab retweeted
I'm excited to share our paper following from @rpavaneijk's work on the use of passive actigraphy for monitoring #ALS #MND function outside the clinic. There is clearly a lot of opportunity to expand the potential of this technology. @Steyn_Lab @Ngo_Lab:
doi.org/10.1007/s00415-023-1…
Thank you for sharing the blog - great summary of the talk by @NgoShyuan
Great to see @NgoShyuan's research getting highlighted;
Why is understanding hypermetabolism important in ALS outcomes? mndresearch.blog/2023/01/12/…
Steyn_Lab retweeted
Does hypothalamus size matter in #ALS? Patients with low hypothalamic volume with low BMI tend to lose fat mass and have increased risk for earlier death. Thank you to the #PALS and their friends and family who contributed to this work. doi.org/10.1111/ene.15589🧠@EANeurology (1/4)
ALT 3D rendering of the hypothalamus and fornix in front of an image obtained using Magnetic Resonance Imaging (MRI).
Steyn_Lab retweeted
So proud to have my first first-author paper, Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T, published in @JOSS_TheOJ with @Fred_Steyn @NgoShyuan Rob Henderson, Christine Guo @sbollmann_MRI Jurgen Fripp @MarkusBarth2 and @thomcat992 ✨🎉🧠
Just published in JOSS: 'Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T' doi.org/10.21105/joss.04368
