@SternLab

Studying the evolution of viruses, microbes, their hosts and beyond at Tel-Aviv University.

 Israel
Joined June 2017
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  • Following358
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Millions of SARS-CoV-2 seqs out there..what info do they hide? Combining phylogeny & deep learning we infer hundreds of chronic infections & show they predict future evolution. Want to know how? ๐Ÿงต biorxiv.org/cgi/content/shorโ€ฆ @SheriHarari @Daniellemlrs @shay_fleishon @BursteinLab
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Heartbroken and shocked. Talented and wonderful Liam who was about to start her Master's degree in my lab, was killed in an accident in Thailand. ืฉื‘ื•ืจืช ืœื‘ ื•ื”ืžื•ืžื”. ืœื™ืื ื”ืžื•ื›ืฉืจืช ื•ื”ืžื‘ืจื™ืงื” ืฉืขืžื“ื” ืœื”ืชื—ื™ืœ ืชื•ืืจ ืฉื ื™ ื‘ืžืขื‘ื“ื” ืฉืœื™, ื ื”ืจื’ื” ื‘ืชืื•ื ืช ื“ืจื›ื™ื ื‘ืชืื™ืœื ื“. ynet.co.il/news/article/hj4cโ€ฆ

ืžืฆื˜ื™ื™ื ืช ื”ื˜ื›ื ื™ื•ืŸ ืœื™ืื ืฉืจื•ื˜ ื ื”ืจื’ื” ื‘ืชืื•ื ื” ื‘ืชืื™ืœื ื“: "ื”ืฉืžื™ื™ื ื ืคืœื•"

ืœื™ืื ืฉืจื•ื˜ ื‘ืช ื”-25, ืฉื”ื™ื™ืชื” ืžืฆื˜ื™ื™ื ืช ื“ื™ืงืŸ ื‘ืžืฉืš ืฉืœื•ืฉ ืฉื ื™ื ื‘ืจืฆื™ืคื•ืช ื‘ื˜ื›ื ื™ื•ืŸ, ื ื”ืจื’ื” ื‘ืชืื•ื ื” ื‘ืžื”ืœืš ื—ื•ืคืฉื” ื‘ืงื• ืกืžื•ื™ ืขื ื‘ืŸ ื–ื•ื’ื” - ืฉื ืคืฆืข ื•ืื•ืฉืคื– ื‘ื‘ื™ืช ื”ื—ื•ืœื™ื. ื”ืื ื›ืชื‘ื”: "ืคืืจ ื™ืฆื™ืจืชื™, ื”ืœื‘ ืฉืœื™ ืžืจื•ืกืง"ย 

ynet.co.il
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Given incredibly difficult, conflict-filled years,it makes me proud to present @BZman101 beautiful work on intra-host evolution in SARS-CoV-2. Briefly,we find evolution differs among patients: in some nothing happens; in others rampant adaptive evolution. academic.oup.com/ve/article/โ€ฆ

Diverse patterns of intra-host genetic diversity in chronically infected SARS-CoV-2 patients

Abstract. In rare individuals with a severely immunocompromised system, chronic infections of SARS-CoV-2 may develop, where the virus replicates in the bod

academic.oup.com
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Science is solace these days and what could be better than studying cheater viruses?? Proud to share our new work that probes what happens when you evolve a point mutant cheater virus. w/ @ugophna biorxiv.org/content/10.1101/โ€ฆ

Navigating a fine balance: point-mutant cheater viruses disrupt the viral replication cycle

Cheater viruses, alternatively denoted as defective interfering viruses, cannot replicate on their own yet replicate faster than the wild type (WT) when the two viruses coinfect the same cell....

biorxiv.org
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4. This is like pulling the strings of a marionette - cheaters change one part of the replication cycle and helpers compensate, all with the "aim" of producing more cheater progeny.
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5. Finally we speculate that cheaters are probably very common and may even serve as stepping stones on the way to generate novel forms of viruses... Stay tuned!
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ืดืืชื” ืžืจื’ื™ืฉ ืฉื™ืฉ ืœืš ืžื•ืกืจ ื™ื”ื•ื“ื™ืด? ืื™ืŸ ืžื” ืœื•ืžืจ ื™ื•ืชืจ. ืจืง ืœื‘ื›ื•ืช. #ืกื•ืฃืœื”ืคืงืจื”
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ืดื”ืžื—ื™ืจ ืฉื ืฉืœื ืขืœ ื”ื—ื–ืจืช ื”ื—ื˜ื•ืคื™ื ื™ื”ื™ื” ื™ืงืจ, ืื‘ืœ ื”ืžื—ื™ืจ ืฉื ืฉืœื ืขืœ ืื™ ื”ื—ื–ืจืชื ื™ื”ื™ื” ื™ืงืจ ื‘ื”ืจื‘ื”. ื›ื™ ืœืขื•ืœื ืœื ื ืชืื•ืฉืฉ ื›ืขื. ืœื ื ื•ื›ืœ ืœื˜ืขื•ืŸ ืฉืื ื—ื ื• ื”ืื•ืžื” ืฉืžืงื“ืฉืช ืืช ื”ื—ื™ื™ื. ืื– ื‘ืืžืช ื ืคืกื™ื“. ื›ื™ ืœื ื ื–ื”ื” ืืช ืขืฆืžื ื•. ื ื‘ื™ื˜ ื‘ืžืจืื” ื•ื ืจืื” ืื“ื ื–ืจ ืžื‘ื™ื˜ ื‘ื ื• ื‘ื—ื–ืจื”.ืด
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ื›ืžื” ื›ื•ืื‘ ื”ื‘ื•ืงืจ ื”ื–ื”. ื•ื”ื›ื™ื ื•ื™ ืžืคืงื™ืจื™ื ืžืžืฉ ืœื ืžืกืคื™ืง ื—ื–ืง ื›ื“ื™ ืœืชืืจ ืืช ื—ื‘ื•ืจืช ื”ื—ืœืื•ืช ืฉื™ื•ืฉื‘ืช ื‘ืฉืœื˜ื•ืŸ ื›ืจื’ืข.
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Heartbroken to share that Yagev Buchshtab, brother of PhD student Nufar, was murdered in Hamas captivity. Too much unbearable pain. This should not have ended, or started, this way.
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ื”ืกื˜ื•ื“ื ื˜ื™ื ื•ื”ืกื˜ื•ื“ื ื˜ื™ื•ืช ืžืคืกื™ืงื™ื ืœืฉืชื•ืง. ืขืกืงืช ื—ื˜ื•ืคื™ื ืขื›ืฉื™ื•! ืžื—ืจ, 8.5, ื‘ืฉืขื” 12:00, ื ืงื™ื™ื ื”ืคื’ื ื” ื‘ืื•ื ื™ื‘ืจืกื™ื˜ืื•ืช ื‘ื“ืจื™ืฉื” ื‘ืจื•ืจื”: ืขืกืงื” ืขื›ืฉื™ื•! ืื ื—ื ื• ืžืชื ื’ื“ื™ื ืœื”ืคืงืจืช ื”ื—ื˜ื•ืคื™ื, ื—ืœืงื ืฉื•ืชืคื™ื ืฉืœื ื• ืœืกืคืกืœ ื”ืœื™ืžื•ื“ื™ื. ื›ืœ ืื—ื“ ืžืื™ืชื ื• ื”ื™ื” ื™ื›ื•ืœ ืœื”ื™ื•ืช ื‘ืžืงื•ืžื. ืื™ ืืคืฉืจ ืœื”ืžืฉื™ืš ื›ืจื’ื™ืœ ื‘ืœืขื“ื™ื”ื. ื™ืฉ ืขืกืงื” ืขืœ ื”ืฉื•ืœื—ืŸ. ื”ืžืžืฉืœื” ื—ื™ื™ื‘ืช ืœืขืฉื•ืช ื”ื›ืœ ื›ื“ื™ ืœื”ื—ื–ื™ืจ ืืช ื›ื•ืœื ื”ื‘ื™ืชื”. ืชืคืกื™ืงื• ืœืฉื—ืง ื‘ื—ื™ื™ ืื“ื! ื‘ืื•ื ื™ื‘ืจืกื™ื˜ื” ื”ืขื‘ืจื™ืช - ืงืžืคื•ืก ื”ืจ ื”ืฆื•ืคื™ื | ืคื•ืจื•ื ืื•ื ื™ื‘ืจืกื™ื˜ืช ื‘ืŸ ื’ื•ืจื™ื•ืŸ - ืฉืขืจ ืกื•ืจื•ืงื”
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SternLab @sternadi.bsky.social retweeted
Lior Pachter@lpachter
14 Mar 2024
80 days ago @SternLab posted this video by her student Nufar Buchstab, a plea for help regarding her brother Yagev Buchstab who was being held hostage in Gaza for 80 days. It's now 160 days.
SternLab @sternadi.bsky.social@SternLab
26 Dec 2023
My brilliant PhD student Nufar, whose brother is a hostage in Gaza for over 80 days. Nothing prepared me to being a mentor under such a scenario. How can we even continue research in the lab?? Please help her, help us, spread this heart-breaking humanitarian call.
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ืฉืžื—ืชื™ ืœื“ื‘ืจ ืขื ื“ืจื•ืจ ืคื•ื™ืจ @drorfo ืขืœ ืื—ืช ืžืฉืืœืช ื”ืฉืืœื•ืช.... ืื™ืš ื”ืชื—ื™ืœื• ื”ื—ื™ื™ื ื‘ื›ื“ื•ืจ ื”ืืจืฅ? youtube.com/watch?v=a7HKWSf7โ€ฆ

ื”ืชืขืœื•ืžื•ืช ื”ื’ื“ื•ืœื•ืช ืฉืœ ื”ืžื“ืข ืคืจืง 1 - ืžื•ืฆื ื”ื—ื™ื™ื

ื”ื”ืชืคืชื—ื•ืช ื”ืžื“ืขื™ืช ื•ื”ื˜ื›ื ื•ืœื•ื’ื™ืช ื”ื™ื ื‘ืœื™ ืฉื•ื ืกืคืง ื”ื”ื™ืฉื’ ื”ื’ื“ื•ืœ ื‘ื™ื•ืชืจ ืฉืœ ื”ื...

youtube.com
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SternLab @sternadi.bsky.social retweeted
John Spencer
@SpencerGuard
30 Jan 2024
IMO Israel has implemented more measure to prevent civilian casualties in urban warfare than any other military in the history of war. This includes many measure the U.S. has (or has not) taken in wars & battles but also many measures no military in the world has ever taken. ๐Ÿงต
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SternLab @sternadi.bsky.social retweeted
Asher Leeks@AsherLeeks
22 Jan 2024
Announcing the Social Lives of Viruses 2024! Do you study social evolution in viruses? Do you want to? Join us in Puerto Rico this June for a 50-person meeting dedicated to viral sociality. All costs covered. Apply here: forms.gle/sHTEcHJjryDhHqZu9 #LoveVirology #SocialViruses
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Our paper is now out nature.com/articles/s41467-0โ€ฆ @SheriHarari @Daniellemlrs @shay_fleishon @BursteinLab I want to be happy but my heart is still torn to pieces with hostages incl. kids,women,elderly, being held for 107 days.

Using big sequencing data to identify chronic SARS-Coronavirus-2 infections

Nature Communications - Chronic SARS-CoV-2 infections have been hypothesised to be sources of new variants. Here, the authors use large-scale genome sequencing data to identify mutations predictive...

nature.com
SternLab @sternadi.bsky.social@SternLab
18 Jul 2023
Millions of SARS-CoV-2 seqs out there..what info do they hide? Combining phylogeny & deep learning we infer hundreds of chronic infections & show they predict future evolution. Want to know how? ๐Ÿงต biorxiv.org/cgi/content/shorโ€ฆ @SheriHarari @Daniellemlrs @shay_fleishon @BursteinLab
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SternLab @sternadi.bsky.social retweeted
Bring Them Home Now
@bringhomenow
18 Jan 2024
Sorry for that. #BringThemHomeNow
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SternLab @sternadi.bsky.social retweeted
Aviva Klompas
@AvivaKlompas
16 Jan 2024
This is Itai Svirsky. He was taken hostage to Gaza on October 7. Hamas forced him to participate in a propaganda video and then murdered him.
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