
Husband. Father of 2 exhausting boys. Director of Biopharma Intelligence @BioCentury. Lives → U.K., roots in Minnesota. Opinions my own. Landscape photography⬇⬇
England, United Kingdom
Joined February 2018
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Hi @anish_koka genuine Q: if placebo group only receives superficial nick in the scalp, won't they or family immediately know they didn't get the real gene therapy? So there is no true blinding, so what's the difference from a historical control?
Replying to @anish_koka
4/ What did FDA ask UniQure to do? Compare their brain injection against a sham intervention — a small nick in the scalp under brief anesthesia. Not 10 hours of surgery. A few minutes. ( I can find no official confirmation from FDA they have asked for a 10 hour sham surgery comparator arm)
FDA staffing exodus degrading oversight biocentury.com/article/65769…
Stephen Hansen 🇺🇦 retweeted
Live from London: #BioCenturyThisWeek podcast discuss takeaways from the #LondonLifeSciencesWeek and expectations for M&A, dealmaking and venture in 2026 #OnTheRoad with @StephenPHansen and @FishburnSimone buff.ly/wJmB2RS
Stephen Hansen 🇺🇦 retweeted
The latest #BioCenturyThisWeek podcast talks the return of Prasad to @US_FDA, why @Lilly's obesity data is better than you may think, Acadia's ambition & Biosecure's revival with @FishburnSimone @SteveUsdin1 @StephenPHansen @SelinaMKoch @Jeff_Cranmer buff.ly/2tXjWAu
Stephen Hansen 🇺🇦 retweeted
$SRPT
without further comment:
Third patient dies from acute liver failure caused by a Sarepta gene therapy buff.ly/G0IbXHh
Stephen Hansen 🇺🇦 retweeted
Third patient dies from acute liver failure caused by a Sarepta gene therapy buff.ly/G0IbXHh
Stephen Hansen 🇺🇦 retweeted
RFK Jr's thimerosal thread is a masterclass in misinformation. Let's fact-check it line by line. 🧵
In conformance with the pharma-financed mainstream media’s mantric ritual of dutifully parroting the propaganda tropes spoon-fed them by vaccine makers and their captive regulators, @guardian on Friday pronounced thimerosal, the ethylmercury-based vaccine preservative, “safe.” Opining under the headline, “CDC vaccine panel to review ingredient RFK Jr has targeted for removal,” The Guardian authoritatively assures: “The preservative has been deemed safe.” The Guardian did not bother to cite any peer-reviewed study.
Journalists don’t seem to read those anymore. Instead, it referenced a fact check website operated by the Pharma-funded American Academy of Pediatrics. @AmerAcadPeds likewise cites no peer-reviewed study to support this claim or its equally terse assertion that “Thimerosal has been removed from all routine childhood vaccines.”
This is another treadworn lie of the vaccine industry. There are high bolus doses of mercury in flu shots, which CDC recommends to pregnant women in any trimester of pregnancy and as a routine vaccine for children at six months and in every year of life. Between conception and age 18, a compliant American child today could get a cumulative load of as much as 500 mcg of ethylmercury from multidose flu shots—nearly double of what they were once getting from all the childhood vaccines put together.
Now let’s look at The Guardian claim that thimerosal is safe.
A quick search at the National Library of Medicine’s PubMed and PubChem websites nets thousands of studies on search terms such as: mercury neurotoxicity,[1],[2] mercury and development,[3],[4] and mercury and brain,[5],[6] and hundreds that identify thimerosal as a potent neurotoxin, carcinogen, mutagen, and endocrine disruptor. There has never been a study that proves thimerosal safe.
In early 2001, Director of the FDA Office of Vaccine Research and Review, the late William Egan, admitted under oath before Congress that thimerosal’s safety had never been studied in human beings.[7],[8] I leave it to the reader to speculate as to why CDC has not performed such studies in the intervening 24 years as it dosed hundreds of millions of American children and pregnant moms with mercury-laden flu shots. Furthermore, CDC has no existing guidelines for safe exposure to ethylmercury.[9]
But let’s put all that peer-reviewed science aside and just look at what the government and the vaccine industry say about thimerosal. Thimerosal’s label advises against its use during pregnancy, pointing out that thimerosal has never been shown to be safe and that it causes mutations in mammals.[10],[11] Thimerosal’s material safety data sheet (MSDS) acknowledges that thimerosal is “toxic,” has “Nervous System and Reproductive Effects,” and is “mutagenic in mammalian cells,” and that exposure to mercury in thimerosal “in utero and in children can cause mild to severe mental retardation and mild to severe motor coordination impairment.”[12]
The MSDS lists a grim inventory of dozens of other devastating injuries from thimerosal exposure.[13]
In 2001, the National Institute for Environmental Health Sciences (NIEHS) revised its thimerosal toxicity statement, warning that thimerosal is “toxic by ingestion and inhalation.”[14]
The California EPA recognizes thimerosal as a reproductive toxicant in the clearest possible language: “Thimerosal dissociates in the body to ethyl mercury. The evidence for its reproductive toxicity includes severe mental retardation or malformations in human offspring who were poisoned when their mothers were exposed to ethyl mercury or thimerosal while pregnant, studies in animals demonstrating developmental toxicity after exposure to either ethyl mercury or thimerosal, and data showing interconversion to other forms of mercury that also clearly cause reproductive toxicity.
The US EPA, the authoritative body relied on when mercury and mercury compounds were listed under California’s Proposition 65, currently identifies mercury and mercury compounds as causing reproductive toxicity.” The amount of ethylmercury in a flu shot is 25,000 times EPA’s safety level for drinking water.[15],[16]
Federal and state laws provide that whenever expired thimerosal vaccines are disposed of, they constitute a hazardous waste.
In 1998, FDA banned thimerosal in all over-the-counter products, ending its use in creams, eye medicine, and disinfectants like mercurochrome. It’s ironic that CDC still recommends its injection into babies.
A 2000 study by the National Research Council found that prenatal and infant mercury exposures cause multiple impacts to basic brain development by disrupting the division and migration of neuronal cells.[17],[18],[19]
According to a National Toxicology Program PowerPoint presentation entitled “Comparative Toxicity of Ethyl and Methyl Mercury”: “Ethylmercury is a neurotoxin. Infants may be more susceptible than adults. Ethylmercury exposure from vaccines (added to dietary exposures to methylmercury) probably caused neurotoxic responses (likely subtle) in some children.”[20]
A 2005 NIH study commissioned by FDA’s Center for Biologics Evaluation and Research (CBER) and performed by the National Toxicity Program (NTP) obliterated the industry claim that the ethylmercury in vaccines is less toxic than the heavily regulated methylmercury in fish, finding that the ethylmercury in thimerosal crosses the blood-brain barrier, lodges in the brain, and metabolizes into the most toxic form of mercury at double the rate of methylmercury.[21] A subsequent study found that this highly toxic mercury remains in the brain for over 27 years.[22]
A 2000 study in Neurotoxicology by Dr. William Slikker Jr., former head of the FDA’s National Center for Toxicological Research, directly foretold the results of a 2005 NIH-funded study, reporting that “Thimerosal (sodium ethylmercurithiosalicylate) crosses the blood-brain and placental barriers and results in appreciable mercury content in tissues including brain.”[23]
A 2017 NIH/CDC study links miscarriage to flu vaccines, particularly in the first trimester. Pregnant women vaccinated in the 2010/2011 and 2011/2012 flu seasons had two times greater odds of having a miscarriage within 28 days of receiving the vaccine. [24]
In women who had received the H1N1 vaccine in the previous flu season, the odds of having a miscarriage within 28 days were 7.7 times greater than in women who did not receive a flu shot during their pregnancy. These results are all the more significant when considering the fact that 7 of the 13 authors on the study had potential conflicts of interest such as having received research support from GlaxoSmithKline, Sanofi, Pfizer, Merck, Novartis, Novavax, and other Big Pharma companies. One author, Frank DeStefano, was head of CDC’s immunization Safety Branch.
It’s noteworthy that these authors chose not to differentiate outcomes between thimerosal-containing flu shots and those that did not contain thimerosal. Around half the flu shots available at that time contained thimerosal.
On October 1, 2001, the Institute of Medicine of the National Academy of Sciences Immunization Safety Review Committee (ISR) issued a report concluding that the link between thimerosal and the rise of neurological injuries in children, including autism, is “biologically plausible,”[25] and recommended the termination of all thimerosal-preserved vaccines.
An entire bibliography of pharmacokinetic studies by independent scientists, prestigious universities, and prominent research institutes published in high-gravitas journals, attest to thimerosal’s powerful neurotoxicity, and show that mercury tends to accumulate (and remain for considerable periods of time, years to decades) in the brains of primates and other animals after injection of thimerosal-containing vaccines.[26]
It’s worth noting just one of these, a well-known Russian study from 1977 led by Dr. N.D. Mukhtarova, found that the majority of adults exposed to much lower concentrations of ethylmercury than those currently given to American children in vaccines were still suffering neurological injury and neuropathology several years after the exposure. These symptoms included decreased vision, hearing, memory, vertigo, and pain and numbness in the hands and feet.[27],[28]
The Guardian is blind and scientifically baseless repetition of empty industry assurances about thimerosal safety is yet another proof that journalists, and particularly science journalists, have now devolved into obsequious stenographers for Big Pharma.
I don't know if this is normal, but seems pretty cheeky for @NintendoUK to actually expect you to buy the "welcome tour" for the new #Switch2 - you can't just give that to customers for free when they've upgraded or are new to Switch? Bad first impression IMO
Look at what NIH funding can achieve...
In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by @US_FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe, rapidly progressing genetic disease... all in an astounding 7 months. Best of all, the infant patient shows apparent benefit. Congratulations to @kiranmusunuru, Rebecca Ahrens-Nicklas, and other team members for this heroic and inspiring effort, which has implications for the hundreds of millions of patients that suffer from thousands of genetic diseases.
drive.google.com/file/d/1Jfk…
Stephen Hansen 🇺🇦 retweeted
Listen to the head of the Port of Los Angeles.
No single person is getting more real time data about the economy than this guy.
He says we are fucked.
Stephen Hansen 🇺🇦 retweeted
HHS Secretary Kennedy made scientifically inaccurate statements to justify holding up approval of the Novavax COVID vaccine buff.ly/pci5yzr
Stephen Hansen 🇺🇦 retweeted
My heart always skips a beat whenever I get the call from my friends at @MakeAWish letting me know we have a “Rush Wish” that needs to happen right away.
On March 11th, I had the privilege of making Kane’s wish come true - and despite not being able to speak when we met, I FELT this little boy’s SMILE, and felt this little boy’s MANA.
His mana was beautiful.
His mana was strong.
One week later on March 18th, brave Kane passed on.
Kane LOVED MAUI and loved bringing his Maui hook 🪝 everywhere he went.
He also wanted to sing “You’re Welcome” 🎶 🌊 and that’s exactly what we did.
He may have been quiet, but in his heart, Kane was just singing away….
To his parents, Charles and Christine, I’m so deeply sorry for your loss. Sending all my love, light and aloha.
Stay strong.
And lastly, to his twin brother, Dennis..
Man you’re an AWESOME brother and I can’t wait to shake your hand one day
🫱🏾🫲🏼
ps… Dennis - thanks dude for helping me sing You’re Welcome… you made it sound good!!!
😅🤜🏾🤛🏻
“He brought so much light to everyone who met him, so I want to continue to share that light” ~ Christine. Kane’s mama.
#kane 🕊️✨🪝
Stephen Hansen 🇺🇦 retweeted
"Not exactly a pick-me-up" says my @BioCentury pal @BioPharmaJosh about the new #BioCenturyThisWeek biotech podcast! But trust him, it's the stuff you need to know about what's happening to @US_FDA & $XBI. w/@steveusdin1 @FishburnSimone @StephenPHansen biocentury.com/article/65548…
Stephen Hansen 🇺🇦 retweeted
This 2016 video is just an incredible two minutes. Every second of it. It will be in the documentary.
Could amylin outshine GLP-1 in obesity? biocentury.com/article/65525…
Could amylin outshine GLP-1 in obesity? biocentury.com/article/65525…


















