The Spangler Lab at Johns Hopkins University integrates structural biology, molecular engineering, and translational immunology to design new disease therapies.

Baltimore, MD
Joined May 2018
Exciting news! #HopkinsBME research landed the cover of @JCI_insight for September.
A complex approach for antitumor activity: insight.jci.org/articles/vie… The Cover features study by Elissa Leonard, Jakub Tomala et al. They engineered a cytokine/antibody fusion protein with important implications for future immunocytokine development. @SpanglerLab @HopkinsMedicine
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👀Preview of Ludwig et al.: Sharks give a handle to potent anti-tumor multiparatopic antibodies inducing membrane depletion of PD-L1 by Gordana Wozniak-Knopp and Veronica Natale at @BOKUvienna @acibGmbH dlvr.it/T6znCd
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Five brilliant minds from Johns Hopkins have been honored as 2024 Siebel Scholars! These scholars are making waves in bioengineering with their outstanding achievements. We're proud to have them represent JHU on this prestigious platform. hub.jhu.edu/2023/09/25/siebe…
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Excited to be in Orlando for #AACR2023 to share our latest on mRNA LNP delivery tech for cancer immunotherapy with @SpanglerLab and @veiseho! Come join the party in room W414! – at Orlando, FL
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SpanglerLab retweeted
Last year 4 ASPIRE Scholars moved on to permanent positions in the academy. @RebeccaKeener9 is a Research Scientist with @alexisjbattle. She credits ASPIRE making her a great mentor. Intentional mentor training is offered by our partner @MorganStateU.
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Congrats to the 2021 Damon Runyon-Rachleff Innovators! Six extraordinary researchers have received five initial grants, and four previous awardees were given “Stage 2” support. Read more about our new #braveandbold Innovators here: bit.ly/3qleTAh and below 🔽
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#HopkinsBME faculty Warren Grayson (@GraysonLab), Casey Overby Taylor, and Jude Phillip are among the 1,000 Inspiring Black Scientists in America. Read more on @CellMentor: bit.ly/381xFUp
Thanks @CellPressNews for creating this list for our scientific community!!
With this final list, @CommofScholars and @phdgprotein86 hope to dismantle the myth that outstanding Black scientists make up a small percentage of the scientific community. Read more in @CellMentor: crosstalk.cell.com/blog/1000…
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The 2020 CMBE Young Innovators issue is coming... see anyone you recognize?
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Super congrats to our local Bioengineeing Siebel Scholars. @JGreenGroup PhD student @Sci_Squirrel, @deniswirtz lab member Alexandra Sneider, @GraysonLab member Sarah Somers, Gilkes Lab member Ines Godet, and last but not least @GerechtLab member Bria Macklin!
We are thrilled to announce the #SiebelScholars Class of 2021. Congratulations to this exceptional community directly influencing the technologies, policies, economic and social decisions shaping our future! #SiebelClassOf2021 Press Release: bwnews.pr/3coFQKV
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Announced today: #HopkinsEngineer Jamie Spangler is 1 of 3 JHU researchers to receive a grant through the Bisciotti Foundation Translational Fund. She will use the funding to pursue a novel way to block cancer from spreading through the body. Learn more: ventures.jhu.edu/news/biscio…
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