@Sleebs_Lab
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Medicinal Chemistry and Chemical Biology Research Laboratory @WEHI_research #cancer #malaria #infectiousdiseases | views are our own
Melbourne, Victoria, Australia
Joined December 2021
- Tweets220
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Pleased @Sleebs_Lab @WEHI_research contributed to research led by Gregory Adams at MSD on the development of peptidomimetics with potent antimalarial activity that target plasmepsin V pubs.acs.org/aidcbc/article-…
Please to share @Sleebs_Lab @WEHI_research on characterisation of new structural classes that exhibit potent antimalarial activity by targeting plasmepsin X pubs.acs.org/doi/full/10.102…
Sleebs Lab retweeted
In @Sleebs_Lab @WEHI _research discovered the ADHQ chemotype exemplified by WJM590 that exhibits potent antimalarial activity by inhibiting plasmepsin X. #ACSInfectiousDiseases
go.acs.org/er1
Pleased @Sleebs_Lab @WEHI_research played a small role in the published research on the discovery of Plasmodium RBC invasion inhibitors lead by Claudia Barnes and Hayley Bullen @BurnetMalaria
sciencedirect.com/science/ar…
Want to know which plasmepsins are the most promising targets of the next generation of antimalarials. Find out in the recently published review by @Sleebs_Lab @WEHI_research
doi.org/10.1002/med.70065
Pleased @Sleebs_Lab contributed a small role in remarkable team led by Paola Favuzza and Alan Cowman @WEHI_research and David Olsen and John McCauley at MSD that developed MK-7602 now in clinical development for the treatment of malaria.
thelancet.com/journals/ebiom…
Please to share @Sleebs_Lab @WEHI_research latest research led my @MadelineDans and @Wenyin_Su demonstrating the on-target activity of plasmepsin V peptidomimetics in Plasmodium falciparum parasites using genetic and proteomic approaches.
pubs.acs.org/doi/10.1021/acs…
Please @Sleebs_Lab @WEHI_research has contributed to a review at @npjAMR led by Emma Mao @UniofAdelaide on the contribution of natural products to the drugs approved to treat disease caused by apicomplexan parasites
nature.com/articles/s44259-0…
Pleased to see our research is published @Sleebs_Lab @WEHI_research led by William Nguyen on the optimization of an antimalarial class that targets ROM8 & CSC1
...stay tuned for more research on the intriguing role of ROM8 & CSC1 in parasite survival...
pubs.acs.org/doi/10.1021/acs…
Sleebs Lab retweeted
Truly honoured to receive the #MCCB2025 Peter Andrews Award for Innovation in Medicinal Chemistry and Chemical Biology. Grateful for the recognition of our work at @NitscheLab and @ANUChemistry! Congratulations to @PScammells on the well-deserved Adrien Albert Award!
Congratulations to our @RACInational MCCB Division award winners, delivering their lectures this morning in Darwin:
@PScammells - Adrien Albert award
@NitscheLab - Peter Andrews award
👏👏👏
#mccb2025
Sleebs Lab retweeted
Exciting Day 3 @RACI #MCCB2025 ! Starting with showstopping stories from GateBioscience's Pat Sharp on the development of Sec61 #inhibitors for Prion disease, & Prof. Avril Robertson @UQ_News on targeting NLRP3 #inflammasomes. Impressive preclinical efficacy fromin both stories!
Sleebs Lab retweeted
#mccb2025 was great for many reasons. Seeing a plenary swim with a croc was one!
Pleased @Sleebs_Lab @WEHI_research has contributed to research led by Aya Taki @UniMelb on the prediction and prioritization of novel anthelmintic candidates using deep learning is published at Int J Mol Sci. mdpi.com/3245704 #mdpiijms via @IJMS_MDPI
Pleased to see our research @Sleebs_Lab @WEHI_research lead by Tony Hodder on the structural analysis of dual plasmepsin V and plasmepsin X inhibitors is now online at FEBS. febs.onlinelibrary.wiley.com…
Pleased to see the review lead by Harry Shanley @Sleebs_Lab @WEHI_research in collaboration with the Gasser Lab @UniMelb on Advances in Anthelmintic Target Identification is now published. mdpi.com/3270800 #mdpiijms via @IJMS_MDPI
Pleased to see our latest research lead by Kyle Awalt and Zi Kang Ooi @Sleebs_Lab @WEHI_research on the investigation of a novel class of antimalarials that target PfATP4 published is now online at the Journal of Medicinal Chemistry. pubs.acs.org/doi/10.1021/acs…
Sleebs Lab retweeted
Congratulations to @UpamaliSajinika from our lab for receiving the poster prize at the #MCCB2025!
Sleebs Lab retweeted
A big THANK YOU to all MCCB 2025 sponsors & exhibitors! Your support drives innovation & makes this conference possible🌟 #MCCB2025
