Illuminating keratinocyte cell biology @DermatologyUW to understand epidermal differentiation/tissue homeostasis and how they are compromised in skin disease.

Joined October 2021
Proud of med student Rafael Homer whose summer research project @SimpsonLabUW @DermatologyUW won 2nd place in the @uwsomwwami Wyoming site poster competition! Rafael also won a travel award to attend the Western Medical Research Conference & was chosen for an oral presentation🤩
1
2
12
619
New paper from @SimpsonLabUW @DermatologyUW is online @JCI_insight🍾We found ERK hyperactivation disrupts cell-cell adhesion in epidermis, linked this pathway to both drug-induced & spontaneous Grover disease & identified MEK inhibition as a novel therapy: insight.jci.org/articles/vie…
1
6
2
21
3,315
Great lunch @SimpsonLabUW⁩ ⁦@DermatologyUW⁩ for lots of celebrating including Arti’s birthday 🥳 More good news to share soon now that I’m out from under the cloud of this R01 submission 😮‍💨📝 ✅🤞
1
18
671
Very proud of Akshata for representing @SimpsonLabUW @DermatologyUW at the @UWISCRM Fall Symposium. She did a great job at her 1st poster session explaining her work developing quantitative methods to assess our model of #HaileyHailey disease, a rare #skin #blistering disorder.
2
18
836
We were sad to bid farewell to Rafael Homer, rising 2nd-year med student (left), who joined @SimpsonLabUW @DermatologyUW for the summer from the Laramie, Wyoming campus of @uwsomwwami @UWMedicine. Thanks for your work on a project to improve our understanding of #Darier disease.
1
7
456
Grateful for an @american_skin1 grant to support our work @SimpsonLabUW @DermatologyUW to understand how #keratinocytes mature via #autophagy to form the outer skin layers and how this is disrupted in thick, scaly #psoriasis plaques (image from DermNetNZ). americanskin.org/news/pr_202…
4
25
1,225
Thank you to @UpliftingAth Researcher Connection Program for providing a travel award for @JessicaLeeAyers from @SimpsonLabUW @DermatologyUW to attend the #Darier & #HaileyHailey Disease Symposium @SocInvestDerm mtg. Her poster was well-attended and she gave an outstanding talk!
1
10
453
@SimpsonLabUW has grown over the summer so we needed two selfies🤳🤩Very proud of this group of curious & collaborative scientists all doing great work to understand skin regeneration and @RareDiseases in #dermatology while teaching me to be a better researcher, teacher & mentor.
1
1
193
Fun happy hour to celebrate CJ @johnsonch20 departing @DermatologyUW to return to clinics @uwsomwwami. Special thanks to @PssfMsrf for supporting his 1-year fellowship @SimpsonLabUW. Look fwd to sharing his awesome work @ASCBiology in Dec and submitting his 1st-author paper soon!
1
1
1
9
656
So proud of @UWM3D PhD student @JessicaLeeAyers (photo #2) for her awesome lightning⚡️talk @UWISCRM Symposium on her thesis project modeling #HaileyHailey disease, a rare genetic skin blistering disorder w/o any FDA-approved therapy. Making @SimpsonLabUW @DermatologyUW shine! 🤩
The 2024 Symposium continues with trainee lighting talks!
1
7
649
Loved seeing @SimpsonLabUW members Afua Tiwaa & @uwsomwwami med student CJ Johnson do a great job explaining their projects @UWISCRM Symposium. Congrats to CJ on his poster prize! They're gearing up for oral presentations in Dallas @SocInvestDerm mtg in just 2 wks!🧫🔬🤩 #ProudPI
1
1
1
6
2,373
Fantastic talk by @DrWoappi imagining new horizons in #regenerative #medicine for #skin. Impressive work addressing wounds which have HUGE impact on quality of life & healthcare💰 Thanks to @UWBioE for giving me a slot for a chat. Hope to see you @SocInvestDerm as a rising⭐️soon!
4
1
18
1,941
Excited to share our paper @theJIDJournal w/@JennyNathans @JShendure reviewing how DNA barcoding can map cell lineages in skin development/cancer & how CRISPR-based DNA Typewriter can be used as a molecular tape-recorder to log biological signals in vivo. authors.elsevier.com/a/1iyKb…
1
5
1
19
1,991
Just 1 mo until our inaugural #Darier & #HaileyHailey Symposium convenes scientists, clinicians & advocates for these rare diseases w/o any FDA-approved drug (appealed another Rx denial for patient today). Join us pre @SocInvestDerm mtg in Dallas Tue 5/14! survey.alchemer.com/s3/76319…
Less than 2 mos until @SocInvestDerm mtg. Join us pre-mtg (Tue 5/14 @ 2pm) for a FREE inaugural symposium on #Darier & #HaileyHailey disease organized by @SimpsonLabUW @KathyGreenLab @CellJxn + fun group dinner w/another org for @RareDiseases @Pachyonychia:survey.alchemer.com/s3/76319…
1
1
2
1,181
Thanks again to @LEOFondet for investing in @SimpsonLabUW @DermatologyUW @UWMedicine to fund our work on Hailey-Hailey disease, a rare blistering disorder. Look fwd to our inaugural symposium on Darier & Hailey-Hailey @SocInvestDerm mtg on May 14--join us! pachyonychia.org/2024symposi…
4
16
1,783
Looking forward to attending @the_asci meeting in Chicago in April. I am very grateful for their support of the clinician-investigator pipeline through this award program that provides networking and career development opportunities for early-stage physician-scientist PIs.
The ASCI is proud to announce our 2024 Early-Career Awardees! Click here for the complete list of awardees: YPSA: buff.ly/3ucQEce E-Gen: buff.ly/3HtWnxC Congratulations to our awardees and to the institutions they represent!
2
12
1,135
Excited our new grp focused on the rare genetic blistering disorders #Darier & #HaileyHailey Disease will partner w/@Pachyonychia for 2 awesome symposia before @SocInvestDerm 2024 mtg. We aim to bring together researchers & clinicians to kindle translational synergy in our field!
Registration is now open for two synergistic scientific meetings, joining forces to understand rare skin disorders & advance research & treatments for patients who suffer from these painful diseases. Learn more & register here: pachyonychia.org/2024symposi…
4
1
11
2,687
Lots of fun @FlatstickPub⛳️ for @SimpsonLabUW holiday party! Not pictured is the scorecard🤫Looking forward to working with this wonderful group of scientists @DermatologyUW in 2024. Happy holidays!
1
6
477
Excited to present at #CellBio2023 in Rm204B @ 3:45p on Organelle Dynamics in Disease. Will show @SimpsonLabUW work spanning cells to patients: depleting Golgi pump SPCA1 in epidermis, we model a rare blistering disease to find new Tx. Join us as a postdoc apply.interfolio.com/113194
2
7
1,103
Super excited to organize (w/@KathyGreenLab & @CellJxn) a pre-mtg @SocInvestDerm focused on translational research for @RareDiseases including blistering disorders #Darier & #HaileyHailey Disease. Thanks to partners @Pachyonychia for helping get the word out RE:our 1st symposium!
Announcing a collaboration to give you two excellent scientific meetings! Mark your calendar and plan to join us in Dallas, TX, on May 14-15, 2024, right before the Society of Investigative Dermatology Meeting. More details and registration coming soon! #Pachyonychia #RareDisease
3
1
12
1,606