Cryo-EM aficionado that used tomography and subtomogram averaging to close the gap between HIV cores and Christmas trees.
Joined October 2017
- Tweets361
- Following484
- Followers1.2K
- Likes1.1K
Pinned Tweet
Upside down! Our latest in situ cryo-ET work shows how cytosolic ribosomes bind mitochondria via their SSU as an adaptive response to cellular stress. A great collaboration with @jomaa_lab! #TeamTomo @embl @EmblImaging
biorxiv.org/content/10.1101/…
Want to know what happens when mitochondria get stressed? Check our latest pre-print with @SimoneMattei19 lab on how mitochondria tether hibernating ribosomes as an adaptive response to glucose depletion in yeast!
biorxiv.org/content/10.1101/…
#teamtomo #cryoEM #ribosomes #mitochondria
Very happy to share that Robert Prevedel and I have been appointed to jointly lead the EMBL Imaging Centre!
Excited to build on its strong foundations and work with our fantastic team to advance imaging services, technology development and image analysis!
EMBL researchers Robert Prevedel and Simone Mattei now jointly lead the EMBL Imaging Centre.
The two look forward to boosting tech development and continuing EMBL's push to advance microscopy image analysis through machine learning & other tools.
tinyurl.com/26yb5nck
Simone Mattei retweeted
After 35 years, the structural biologist Christoph Müller has a new title: Emeritus Scientist. His career at EMBL is marked by lauded research and important mentorship.
Now he begins his next chapter.
embl.org/news/people-perspec…
Join our team at EMBL Imaging Centre!
We are looking for a Microscopy Specialist with strong expertise in super-resolution cryo-light microscopy.
Apply here:
embl.wd103.myworkdayjobs.com…
Simone Mattei retweeted
Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group @UVA and @simonemattei @EMBLHeidelberg
nature.com/articles/s41586-0…
Simone Mattei retweeted
Despite its name, SNOR, a newly discovered protein, is hardly asleep on the job.
EMBL researchers’ newest technologies allowed them to discover this tiny protein with a big role that awakens cells from dormancy to restart protein synthesis.
embl.org/news/science-techno…
Simone Mattei retweeted
Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: biorxiv.org/content/10.1101/…
Grateful to the Boehringer Ingelheim Stiftung for their renewed support. Their commitment empowers us to further advance our mission: enabling broad access to state-of-the-art imaging technologies for the scientific community
Boehringer Ingelheim Stiftung has committed €7 million to EMBL’s Imaging Centre.
That means more opportunities to create groundbreaking, next-gen imaging technologies & provide necessary support to European life scientists.
embl.org/news/connections/ne…
Simone Mattei retweeted
Check out our latest preprint with Qi lab on the structure and disease physiology of the human ERAD complex. Outstanding work by Leo, a cell physiologist whom we successfully tempted into structural biology! Preprint: biorxiv.org/content/10.1101/…
Thanks to @instructhub funding the @EmblImaging Centre is able to offer an advanced hands-on workshop on cryo-FIB-SEM methods. This is a great opportunity to exchange knowledge with our fantastic cryo-CLEM specialists! Apply here before May 12th: embl.org/about/info/imaging-…
(1/3)
📣 Apply now: @instructhub INSTRUCT-ERIC hands-on #workshop: Advanced cryo-FIB-SEM methods on 21-25 July 2025. Limited to 12 participants. Apply before 12th May 2025.
Simone Mattei retweeted
The @ChanZuckerberg Initiative is funding two EMBL projects, coordinated by @EmblImaging, to support imaging technologies development. 🔬
The projects will integrate advanced microscopy techniques to improve the understanding of biological systems.
embl.org/news/science-techno…
Simone Mattei retweeted
Science meets art at the EMBL Imaging Centre! 🔬🎨
Several scientists shared their experience as users of this facility and explain why it is a unique place to turn your research into stunning, informative images.
Read the full article here 👉 embl.org/news/connections/fr…
Simone Mattei retweeted
Niels Weidemann edited a volume of Methods in Enzymology on mitochondrial import. I was honoured to write a review about yeast genetics together with Maya Schuldiner! I hope it will be useful.
doi.org/10.1016/bs.mie.2024.…
It’s great to see our hibernating ribosomes story finally out @NatureComms! Thanks to @jomaa_lab @MedicineUVA and all @EMBL and @EmblImaging people that supported this project. rdcu.be/dWnv6
Happy to share our little discovery with @SimoneMattei19 team on how ribosomes hibernate upside down on mitochondria during cellular stress is now out @NatureComms! A collaboration between @medicineUVA, @EMBL, @EmblImaging, MEMC. Congrats to all authors! nature.com/articles/s41467-0…
Simone Mattei retweeted
What if we could peer inside a living organism + watch biology unfold in real-time...down to the microscopic level? 🔬 Researchers like @Prevedel_Lab are working to make this ultra-high res deep tissue imaging possible!
Fantastic news! All the best for this scientific journey Yura!
I am very honored to get the @ERC_Research StG and looking forward to the next 5 years of exciting research. I am grateful to my mentors and colleagues who helped me along the way!
rptu.de/en/newsroom/neuigkei…
Simone Mattei retweeted
Registration now to the @EMBL Imaging Centre User Symposium 2024!
Don't miss this opportunity, especially:
✅ limited workshop by @LeicaMicro and @zeiss_micro
✅ 10 speakers from different expertises
More info & registration: embl.org/about/info/imaging-…
#ImagingTechnology
Simone Mattei retweeted
How do karyotypes evolve? Turns out an intracellular tug of war within the metaphase spindle sets the limits for chromosome number evolution. Excited to see our study out today in @NatureCellBio nature.com/articles/s41556-0… 1/9
Simone Mattei retweeted
This is the one 👇🏻
#EMBOCLEM is back and open for applications! 🌟 Learn all about in situ correlative light and electron microscopy while networking and interacting with the experts in the field 🔬 🥼
Course modules include:
🔸 High pressure freezing
🔸 Freeze substitution
🔸 Plunge freezing and micropatterning
...and more!
💻 s.embl.org/lem25-01
⏰ Apply by 17 Nov
🌍 EMBL Heidelberg
📅 9 – 14 Feb
Be sure to apply soon, as this course is in high demand. We hope to see you in February! 🙌
Simone Mattei retweeted
We are looking for an experienced light microscopy specialist to support the Advanced Light Microscopy Facility @embl Heidelberg: embl.org/jobs/position/HD026… - closing date 5 August 2024
@EuLiMI1 @EuroBioImaging @GerBI_GMB @Fr_BioImaging @GlobalBioImage @BioImagingUK
Simone Mattei retweeted
(1/3)
Don’t miss the opportunity to join us at the @EMBL Imaging Centre User Symposium 2024 will be held on 17 to 18 October 2024. Do not miss the deadlines and secure the limited spot. #imaging #CryoEM #superresolution #microscopy.
Read more®ister: shorturl.at/B3FeB
