@SignerLab

Deputy Director - Sanford Stem Cell Discovery Center, Associate Professor of Medicine, UC San Diego. Unlocking the mysteries of stem cells. Opinions are my own.

 @UCSanDiego
signerlab.com
Joined November 2016
  • Tweets706
  • Following726
  • Followers1.8K
87Media
I’m thrilled to share the upcoming Hertzberg-Schechter Stem Cell Workshop: a collaboration between UC San Diego SSCI Discovery Center & the Weizmann Institute, highlighting emerging research on stem cells in cancer & aging. Oct 15, 2025 | 12–5:30PM Register to secure your spot!🌟
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‼️👇🏽👇🏽 The 2024 Myeloid Workshop will occur at the Museum of Contemporary Art in San Diego. Registration is required (but free) for this event, please register asap; attendance is capped. bit.ly/3ULm9nN
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Robert Signer retweeted
ISEH@ISEHSociety23 Aug 2024
Don't miss the latest #SimplyBlood 🩸 blog post, featuring the ISEH 2024 Janet Rowley Award Winner, Dr. Robert Signer (@SignerLab). Dr. Signer shares his career path to becoming a PI, mentorship, and more! Read more on simplyblood.org/
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bit.ly/4cBjfIx Save the Date our annual Sanford Stem Cell Institute Symposium October 17-18, 2024 in La Jolla CA #stemcells #UCSD #UCSanDiego #research
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Robert Signer@SignerLab17 Aug 2024
Help get me on stage at @SXSW ’25 by voting for my panel, “Guardians of Youth: Stems Cells & Human Longevity.” Visit: bit.ly/3YKsCCf before Sunday night. #SXSW #Longevity #HealthyAging #Healthspan #AntiAging
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Dudakov Lab@Dudakov_Lab7 Aug 2024
With a mix of pride, enthusiasm, and tremendous relief, I present our latest paper that describes the emergence of atypical epithelial cells in the thymus with age that limit the tissues function at steady-state and its repair after damage… 1/? nature.com/articles/s41590-0…

Age-related epithelial defects limit thymic function and regeneration

Nature Immunology - Here the authors identify age-associated changes in the epithelial cell compartment of the thymus that form high-density nonproductive microenvironmental niches that contribute...

nature.com
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Excited to share our lab's latest work online today @CellReports @DiegoLopezPhD cell.com/cell-reports/fullte…

Prenatal inflammation remodels lung immunity and function by programming ILC2 hyperactivation

López et al. report that prenatal inflammation induces lung ILC2 expansion and hyperactivation programmed from a fetal hematopoietic progenitor. Increased IL-5 and IL-13 production from hyperactiva...

cell.com
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Andre Catic@Catic_Lab1 Apr 2024
Out now! Our newest paper on how blood stem cells retain their regenerative potential and vitality with age. Paper link: nature.com/articles/s41556-0… More info and video abstract: tinyurl.com/4u7hud78 #StemCells #Aging #Hematopoiesis Summary below:
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Vijay Sankaran
@bloodgenes22 Jan 2024
Fantastic to have our paper "Deciphering cell states and genealogies of human hematopoiesis" published today in @Nature as an Accelerated Article Preview! We describe ReDeeM! Awesome work led by @chenweng1991 in a wonderful collaboration with @JswLab! nature.com/articles/s41586-0…
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Please join us today from 3-4pm for Dr. Fuchs seminar!
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I am thrilled and honored to share our lab's most recent work from the highly talented Diego López @___Dlopez___ as a preprint , available now on BioRxiv: biorxiv.org/content/10.1101/…

Prenatal inflammation reprograms hyperactive ILC2s that promote allergic lung inflammation and...

Allergic asthma is a chronic respiratory disease that initiates in early life, but causal mechanisms are poorly understood. Here we examined how prenatal inflammation shapes allergic asthma suscept...

biorxiv.org
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bit.ly/3YIHmzT Registration is open for our Sanford Stem Cell Institute Symposium 10/19-10/20. Join in-person or virtually at no cost #stemcells #UCSD #UCSanDiego #stemcellsyposium
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PLEASE RETWEET!!! @ucsdbe and @UCSDJacobs is hiring for multiple Assistant Professor positions in #Bioengineering. Come join our diverse group of amazing faculty, students, and staff! #DiversityInSTEM #AcademicChatter #AcademicTwitter apol-recruit.ucsd.edu/JPF037…
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UC San Diego FIRST Program is hosting an information session webinar for potential applicants on Sept. 13! Register for the webinar at go.ucsd.edu/3YCyknX. Registration required. #hiring #TenureTrack #AssistantProfessor #academia #sciencejobs #postdoc #STEMM #AcademicTwitter
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The next cycle of the applications is now open! UCSD is hiring new diverse Assistant Professors through the #NIHFIRST Program! First review date: Oct. 1st. Learn more at first.ucsd.edu. Apply now at apol-recruit.ucsd.edu/JPF036…
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Today, we get to see IN PRINT what happens when the beauty of megakaryocytes and the brilliance of @nubama combine I could not be more excited to share our publication, revealing that both MK maturation and platelet production rely on membrane PUFAs. 🧵👇 rdcu.be/dg3aH
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GutkindLab@SilvioGutkind13 Jun 2023
So excited to share our new publication in @NatImmunol! We leveraged new bioinformatics pipelines and a synthetic biology approach to identify a novel GPCR-Gs-PKA immune checkpoint promoting T cell exhaustion and cancer immunology failure. nature.com/articles/s41590-0… @NCIEytanRuppin
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Anna E. Beaudin@BeaudinLab1 Jun 2023
Excited to share the latest work from our lab investigating the response of fetal hematopoiesis to congenital infection, out today in @embojournal . Truly exceptional work by students @DiegoL011412 @KellyOtsuka and April Apostol, in collaboration with Kirk Jensen @toxobgondii
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Vijay Sankaran
@bloodgenes2 May 2023
Delighted to have our paper, led by @jmartinrufino, on conducting massively parallel base editing screens in primary human hematopoietic cells out in @CellCellPress today. Can help improve therapeutic approaches for #leukemia and #sicklecell disease: cell.com/cell/fulltext/S0092…
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Online debut of the new new 🔥 from the MK to Plt Group with @JosepItaliano Our new story in @RPTHjournal- Fearlessly led by @julia_tilburg and @andystone93 using single cell spatial to show that where MKs are in the bone marrow matters!! 🦴 sciencedirect.com/science/ar… – at Somerville, MA
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