Professor @umanitoba, Neurobiology of Autism n Schz., Molecular logic of neural circuits, Synapse Organization, Science advocate, President @manitobaneuro
Winnipeg, Manitoba
Joined June 2018
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I am pleased to share our paper showing that the minimal neurexin-1 isoform Nrx1γ forms a nanoscale trans-synaptic bridge aligning presynaptic release machinery with AMPAR nanodomains, tuning synaptic transmission and behaviour.
Full access at authors.elsevier.com/a/1nTlG…
Online now: Neurexin-1γ drives synaptic transmission through structural integration of neurotransmitter release machinery and postsynaptic receptor nanodomains dlvr.it/TTdskn
Tabrez J. Siddiqui retweeted
So happy to welcome Ismail into the drug world! This exciting project brings together chemistry with optical tools and models of drug reward and withdrawal! If you are looking for a post-doc, this is a golden opportunity!
Excited to announce we got an @NIDAnews AVENIR DP1 grant.
We are looking for a postdoc to join the group!
Tabrez J. Siddiqui retweeted
Excited to announce we got an @NIDAnews AVENIR DP1 grant.
We are looking for a postdoc to join the group!
Tabrez J. Siddiqui retweeted
“Sleuths say Thermo Fisher doctored data to sell antibodies.”
cen.acs.org/articles/104/web…
To date, 127 images for 119 products have been flagged.
zenodo.org/records/20402476
Tabrez J. Siddiqui retweeted
🚨 Please consider posting a comment to the NIH regarding the Strategic Plan that includes reducing funding for animal research. Responses from the research community are currently greatly underrepresented compared w/ advocacy groups opposing animal experimentation.
🔗 below ⬇️
ALT Image of racks of zebrafish tanks. Credit to NC3Rs. https://www.nc3rs.org.uk/events/guide-refinement-fish-species
Tabrez J. Siddiqui retweeted
@CIHR_IRSC 11% funding rates will slowly destroy our health research ecosystem. We continue to hire more researchers, and we want to do so, of course, with so many brilliant minds around, yet funding remains the same or decreases.
Tabrez J. Siddiqui retweeted
⚠️TYLENOL & AUTISM—RFK Jr and Trump are wrong—the largest & best study in the world in 2.5 MILLION KIDS—found no increased autism risk with acetaminophen (aka paracetamol, Tylenol) use by the mother during pregnancy. A crude unadjusted analysis found only a preliminary 5% risk, but once you adjust for family by matching using sibling controls (who didn’t get autism), the even tiny 5% risk vaporizes to 0% 📉. (Fun fact: I used to do drug safety epidemiology and have been whistleblower against big pharma when their drugs were dangerous—so I know a few things about drug safety data). Thread 🧵.
Tabrez J. Siddiqui retweeted
The really galling thing about the Acetaminophen thing is that the observations of a potential link between its use in pregnancy and autism WERE taken seriously, and WERE studied using "gold standard science", and found not to be there. The same thing is true of the link to vaccines. The only gaslighting that's happening here is repeatedly pushing disproven theories that will help no one, and harm many. jamanetwork.com/journals/jam…
Tabrez J. Siddiqui retweeted
Get ready to meet candidates by reading the CAN election one-pager! We encourage you to print it out and give it to candidates you meet, to emphasize the importance of science and research for all Canadians. #VoteScience #ResearcherVote
can-acn.org/can-election-one…
Tabrez J. Siddiqui retweeted
E4D has done the work. Check out the Party Platform Analysis: docs.google.com/document/d/1… @E4Dca #VoteScience
Tabrez J. Siddiqui retweeted
📢 Spread the word, researchers: We can #VoteOnCampus April 13-16. Let's help students #VoteScience🇨🇦too!
Avis aux chercheur.e.s! 👉Votez sur vos campus du 13-16 avril. Et aidons nos étudiant.e.s à #VoterRecherche aussi🗳️
#VotonsRecherche #ResearchersVote
#Elxn45
Les services de vote sur campus sont prêts! Le vote sur campus commence le dimanche 13 avril et se termine le mercredi 16 avril. Consultez la liste complète des campus participants : elections.ca/content2.aspx?s… (1/2)
ALT Une personne portant un sac à dos tient un bulletin de vote dans sa main.
Tabrez J. Siddiqui retweeted
To insult two highly respected and free thinking politicians like this is disgraceful.
It just shows how far standards in society have fallen.
Anyone reposting this insulting photograph should feel utterly ashamed.
😡
Tabrez J. Siddiqui retweeted
More fentanyl was dispensed by Trump’s White House doctor per the pharmacy logs from his first term than what is crossing the border from Canada.
Beautiful story.
Memory engram synapse 3D molecular architecture visualized by cryoCLEM-guided cryoET biorxiv.org/cgi/content/shor… #biorxiv_neursci
Tabrez J. Siddiqui retweeted
The power to repair in a tiny fish! Taking regenerative medicine to new heights at the University of Manitoba! @UM_RadyFHS @umanitoba @um_HACS_GSA @StemCellNetwork @manitobaneuro @can
