Pathologist, PGY 3+2
New Delhi, India
Joined March 2021
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🫣
When sclerosing epithelioid fibrosarcoma does its best to mimic osteosarcoma, it's MUC4 to the rescue! #BSTpath
ALT MUC4 IHC
Sherrin Jacob retweeted
🔬 Benign or Malignant❓ ~ Focus of glands in TURP specimen... Comment your choice below... and tomorrow, I will show the PIN-4 stain! #GUpath #Pathology #PathResidents
Sherrin Jacob retweeted
🧩 Kidney riddle
Is every renal tumor an RCC or AML?
Before it was described, this entity could be quite scary.
What is your diagnosis?
#DxMindMap #Kidneytumor #GUPath #PathTwitter @JHUpath
Sherrin Jacob retweeted
How long have we known about glomeruli? Today’s teaching point is offered in honor of Marcello Malpighi (1628-1694), the Italian anatomist who is credited with having published the world’s first accurate description of glomerular structure (Bologna, Italy 1666). We learn from those who teach us!
Bellomo G. A short history of 'glomerulus'. Clin Kidney J. 2013 Apr;6(2):250-1. PMID: 26019863
Fogazzi GB. The description of the renal glomeruli by Marcello Malpighi. Nephrol Dial Transplant. 1997 Oct;12(10):2191-2. PMID: 9351094.
Image Credit (for oil painting, Malpighi): Wellcome Collection (wellcomecollection.org/)
#TeachingPoints #kidneypath #renal #pathology
Sherrin Jacob retweeted
Palate. What is your diagnosis? 🔎
Poll below 🗳️👇
#PathPuzzle 🕵️♂️
@UMichPath #Pathology #PathX #PathTwitter
Sherrin Jacob retweeted
New #OpenAccess review by N. Paul Ohori MD of @UPMCPathology et al details the fascinating history of PTC nuclei & summarizes the major events representing the paradigm shifts, classification system changes, and controversies: acsjournals.onlinelibrary.wi… #CytoPath #ENTPath
A quick glance through confusion
#PathQuiz 🔬🦴 #BonePath
10-year-old boy presents with anterior tibial bowing.
A) Fibrous Dysplasia
B) Low-grade central osteosarcoma
C) Adamantinoma of long bones
D) Osteofibrous Dysplasia
#Pathology #BonePath
ALT Woven bone with prominent osteoblastic rimming surrounded by spindle-shaped cells @IARCWHO
ALT Axial CT showing the tumor is confined to the cortex without medullary involvement @IARCWHO
Sherrin Jacob retweeted
A good 🔬clue to distinguish between mucocele-like lesion (MLL) vs. mucinous carcinoma is the frequent presence of neovascularization in the latter.
Dr. Nour Seige, challenges in breast pathology, Romanian National Congress of Anatomical and Molecular Pathology, First Edition, Bucharest, Romania
#breastpath #PathTwitter
Sherrin Jacob retweeted
Metastases to Small Intestine
- Colonize surface mucosa, creating the impression of a "precursor"
- Asynchronous architecture and cytology
- Patchy surface involvement
- Predominantly intravascular distribution
Uterine (endometrioid) carcinoma metastatic to small intestine (pic 2)
Prostate cancer metastatic to small intestine (pics 3-4)
Always check history if available
Dr. Panarelli - 2025 Diagnostic Pathology Update #USCAP #PathX #PathTwitter
Hands down; an important bookmark! 2026 seems to be on fire!
I'm working on a teaching presentation on Hodgkin's lymphoma.
Picture below contains HRS-like cells from 9 different cases.
Which ones are classical Hodgkin's lymphoma and which ones are something else?
#hemepath #pathtwitter #pathology
If your new year resolution was to exercise, here’s a workout for the pathology brains!! Happy new year everyone!! ✨
Happy New Year to everyone! First case of 2026.
Female in her 50s. Multiple mixed sclerotic and lytic lesions involving the thoracic spine and pelvis.
#PathX #PathTwitter #BSTPath
Sherrin Jacob retweeted
New in #HumPathol: Colloid cysts of the third ventricle show consistent expression of PAX8 but lack other features of thyroid, müllerian or intestinal differentiation. sciencedirect.com/science/ar… #pathology #PathTwitter #PathX #neuropath
A wonderful tweetorial to cover the bases. #PathX #PathTwitter
The Epigenetic Engines of Cancer: Decoding the SWI/SNF Complex 🧬⚙️
From the brain (AT/RT) to the lung (SMARCA4-def) to the kidney (MRT). Different organs. Different ages. Same Molecular Culprit.
Why does the loss of one "Chromatin Remodeler" create the most aggressive, chemo-resistant tumors?
A Mega-Thread on SWI/SNF, SMARCA4, & INI1. 🧵👇
#PathX #PathTwitter #MedEd #Oncology
