
Bio Investor, Entrepreneur, Philanthropy, Dad. Insta: Sheffbiotech. Get it Done! Not InvestAdvice! @VIPSheffTrades-https://xitter.cf/t.co/jw2hZa7L7S
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Joined July 2010
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Brand new guys!! Listen & watch. Great stuff here & awesome plays to be watching for. 👊🏽 Please like it & RETWEET! Trying to get 250k views on this one. Greatly appreciated!!
The "two-trial dogma" is over. 🧬
The FDA's new one-pivotal-trial shift is the new default for 2026, and it’s rewriting trial timelines and cash runways. In biotech, this isn't just a rule change—it's a survival metric.
Full breakdown with John & @SheffStation :
🎧listen here: youtube.com/watch?v=0EGusAkr…
#biotech #FDA #stocks #investing
Sheff retweeted
Did you know?
Vance Sheffield has three game-winning goals this season, which leads the @HorizonLeague and is tied for fourth-best in the nation.
$RNTX … $.88 … look at the increased positions vs decreased. Look at all the new shareholders from 6/30 filings which came out a few weeks ago!! Data YE26 w/ a few investor conferences & some data next week!
Sheff retweeted
Rein presenting late-breaking poster at #ERS2026 in Barcelona highlighting data from our randomized dose-escalation study of inhaled LTI-03 in idiopathic pulmonary fibrosis.
📅 Sept. 8 | 12:30–2:00 p.m. CEST
📍 Poster PA6217
🎤 Philip Molyneaux, MD
Data published in Nature Communications.
$RNTX #IPF #PulmonaryFibrosis
Sheff retweeted
CEO Brian Windsor will present at two investor conferences in NYC this September:
📍 Cantor Global Healthcare Conference
Sept. 11 | 8:00 a.m. ET
📍 H.C. Wainwright Global Investment Conference
Sept. 14 | 11:00 a.m. ET
Watch the presentations live through the Events & Presentations section of our website, with replays available afterward.
$RNTX
R.I.P 💚 Dolly!
JUST IN: Country music icon Dolly Parton, 80, has died.
Her nephew, Brian Seaver, made the announcement on Instagram.
"My name is Brin Seaver, son of Cassie Parton, and I’m representing the Parton and Owens family today announcing the passing of my aunt, Dolly Rebecca Parton Dean, Sister, Sis and Granny to one generation and Gigi to the next."
"This video announcement is something Dolly asked of me years ago, before I fully absorbed it as a future reality..."
Rest in peace.
$SPRB .. $62.41 ..BRiley Securities … SPRB completes tech transfer, and newly disclosed FDA alignment de-risks the gating analytical report, residual CMC risk, and keeps
the 4Q26 BLA submission timeline intact. PT $160
Sheff retweeted
🟢 INSIDER BUY — $PTIX
Armen Garo H buys $13K
• 20,000 shares @ $0.65
• Position +37%
• Stock −87% from 52W high
• Trade: Aug 21, 2026 | Filed: Aug 24, 2026
💡 Moderate Signal
#InsiderTrading #PTIX
Sheff retweeted
Ryan Swan Receives Contract Extension niuhuskies.com/news/2026/8/1…
Sheff retweeted
🚨🚨🚨BREAKING CANCER NEWS! 🚨🚨🚨
Merck $MRK and Moderna $MRNA personalized mRNA cancer vaccine slowed the return of melanoma and its spread to other parts of the body in a Ph3 clinical trial.
No data disclosed yet, but the study was stopped for positive results at the first interim analysis.
Magnitude of benefit TBD, but this is a potentially huge breakthrough for cancer patients and the use of mRNA to treat cancer.
Read STAT's story from @matthewherper and @angRchen
statnews.com/2026/08/19/mrna…
Thx Jay! Makes sense.
Replying to @SheffStation
CITM-76 the big one at this point. I think theyll release updated QW data in Q4. I emailed IR to confirm and waiting to hear back. CT-202 more potential than CT-95. So they trimmed the fat.
Thank you sir! Been a great play. One that can be traded many times. Key catalyst is YE approval. Best of success.
Replying to @SheffStation
great call. watch Vera. 102weel trial data in Q3, sold off due to Otsuka news. this is a recurring theme then she comes back to 3bn cap over and over again
$CNTX …$.50 AH .. 80% tutes holding & other products in pipeline. 43m in cash as of today’s earnings call. One Catalyst now in Sept it’s just that the CT-95 was the bigger one of the expected two. Have till new yr to be Nasdaq compliant & get over $1. No R/S approval in place.
Replying to @SheffStation
Catalyst desert for 6-9 months….will probably drift to 20 cts….and r/s. Will not survive unless stellar data & PIPE somewhere next year
$CNTX ..$.55 in AH… just happened in earnings today! from hero in the hero to zero or discontinued in their case! CT-95.
”As part of a portfolio prioritization and capital allocation strategy, Context is discontinuing the development of CT-95 and will focus its development efforts on CTIM-76 and CT-202.”
$CNTX .. $.65 … trading near 52wk low of $.55 & pancreatic cancer read in Sept 2026. Also another catalyst in Sept. This was $2.50 before the June CTIM-76 data in pretreated ovarian cancer pts in June. Sept data for CTIM-95 looks promising. 80% institutional holdings here.
$CNTX .. $.65 … trading near 52wk low of $.55 & pancreatic cancer read in Sept 2026. Also another catalyst in Sept. This was $2.50 before the June CTIM-76 data in pretreated ovarian cancer pts in June. Sept data for CTIM-95 looks promising. 80% institutional holdings here.
Replying to @SheffStation
That’s % ownership not of their portfolio
$ADGM … $.90… ADAR Capital Mngmt. Avg price in at $1.78. 4th largest position in their portfolio from what I see. 🤷🏽♂️

























