@SekiLabs

Sensorimotor neuroscience lab at NCNP, Kodaira, Tokyo, Japan. Tweets from our lab on the cortical- and subcortical control of limb movement and its disorder.

 Kodaira, Tokyo, Japan
ncnp.go.jp/nin/guide/r_model/index.html
Joined November 2019
  • Tweets109
  • Following131
  • Followers279
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Check out our new manuscript. Our study demonstrates the remarkable ability of the #CNS to adapt #motor_control to long-term internal changes, even after significant alterations to the #musculoskeletal system.
Dr. Roland Philipp@myprefrontal22 Oct 2024
Finally! Still needs to go through peer review but having it out on @biorxiv_neursci is a very important first step. Fingers crossed 🤞@SekiLabs @ValeroLab @OyaTomomichi @NCNP_PR @ncm_soc #tenodesis #tendon_transfer #musclesynergy #electromyography
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In @eLife: Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization doi.org/10.7554/eLife.108684…

Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization

Long-term motor recovery after musculoskeletal alteration relies on gradually developing novel compensatory movements to overcome the rigid, maladaptive timing of stable muscle synergies.

elifesciences.org
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New paper! We demonstrate, at the single-neuron level in primates, that spinal circuits mediating autogenic (Ib-related) positive feedback are actively engaged during voluntary movement and contribute to the generation of skilled hand motor output. pnas.org/doi/10.1073/pnas.25…

Autogenic spinal excitatory circuit ensures skilled hand movements in primates | PNAS

Skillful hand movements are a hallmark of primates, including humans, requiring sophisticated motor planning and execution. Building on the well-es...

pnas.org
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Science Advances に論文が掲載されました！ 霊長類の手はなぜこれほど器用なのでしょうか？ 脊髄と大脳皮質に存在する進化的に異なる神経回路が協調し、安定性と柔軟性を両立させることが「巧みさ」を生み出している可能性が示されました。 science.org/doi/10.1126/scia…

Primate dexterous hand movements are controlled by functionally distinct premotoneuronal systems

Distinct spinal and cortical pathways coordinate muscle synergies and fine control to support primate dexterous hand movements.

science.org
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Our paper is out in Science Advances! What makes primate hands so dexterous? We show that evolutionarily distinct spinal and cortical pathways work together to balance stability and flexibility, supporting remarkable primate hand control. science.org/doi/10.1126/scia…

Primate dexterous hand movements are controlled by functionally distinct premotoneuronal systems

Distinct spinal and cortical pathways coordinate muscle synergies and fine control to support primate dexterous hand movements.

science.org
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【MC冬の学校2025】参加申し込み開始しました！ 学際的な分野であるMotorControl研究の垣根を取り払うべく、理論・実験・臨床の各分野の若手が切磋琢磨する場と2018年に始まった「MC冬の学校」が今年も開催されます！MC会員は参加費無料ですので皆様是非ご参加下さい！sites.google.com/view/mcwint…
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This study explores how the central nervous system (CNS) adapts to long-term changes in the musculoskeletal system using a tendon transfer model in macaque monkeys. biologpt.com/?q=Paper%20Revi…

Paper Review: Multi-timescale neural adaptation underlying long-term musculoskeletal reorganizati...

bgpt.pro
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Did you attend #NCMDub24 or are interested in what was presented? Take a look at the meeting highlights article written by some of the scholarship recipient. onlinelibrary.wiley.com/doi/…

Emerging perspectives for the study of the neural basis of motor behaviour

The 33rd Annual Meeting of the Society for the Neural Control of Movement (NCM) brought together over 500 experts to discuss recent advancements in motor control. This article highlights key topics...

onlinelibrary.wiley.com
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I am grateful to @SekiLabs for his continuous support and to @OyaTomomichi for running with me. Without them, I would not have been able to complete this >10-year (!!) project. We look forward to your comments and suggestions!
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Spinal and cortical premotor control of primate dexterous hand movements biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Arm movements are disrupted by unmodulated stretch reflexes. We propose a spinal cord circuit that could be as good as and complement mechanisms mediated by the brain & cerebellum. This has implications to the emergence and treatment of movement disorders. valerolab.org/Papers/2024_ni…
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Congrats to Shinji! This wouldn't have been possible without you and @OyaTomomichi. Selective recording from the cuneate in behaving NHPs will revolutionize the field! We dedicate this paper to @[email protected], the pioneer behind this challenge.
shinji kubota@kubota1983070711 Mar 2024
New paper from our lab finally officially published in @CellReports: “Modulation of somatosensory signal transmission in the primate cuneate nucleus during voluntary hand movement” You can find a summary in this thread (1/10).
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The NCM 2024 program is now available. We received a record number of submissions this year! There is still time to submit posters - abstracts are due by Feb 19.
NCM society@ncm_soc23 Jan 2024
The program is now available for #NCMDub24! Join us in Dubrovnik to hear all the amazing talks. Submit a poster for consideration before Feb 19 deadline. ncm-society.org/program/
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／ 【拡散希望】マーモセット研究会開催！ ＼ プログラム🐒 sympo.adthree.net/jsmr2023/p… 特別講演 「日本のマーモセットの由来と変遷」 「社会的コミュニケーションの困難に対する治療薬開発：社会行動の客観定量解析と脳分子イメージングによるマーモセットとのトランスレーショナル研究」 他多数...!
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/ 日本マーモセット研究会大会のお知らせ \ 開催まであと【３０日】！！！ ４年ぶりの対面開催です。 一部ハイブリッドのプログラムもございます。 詳細は大会HPをご参照下さい🐒 sympo.adthree.net/jsmr2023/p… #NCNP #研究会情報 #マーモセット #マーモセット研究会
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The program for #NCMDub24 is now live! Check it out here: ncm-society.org/program/. Looking forward to seeing everyone in Dubrovnik!

Program - NCM Society

ncm-society.org
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Scholarship applications for #NCMDub2024 opened yesterday, due December 4. Open to NCM members who are currently students OR within 6 years of earning their PhD!!
NCM society@ncm_soc31 Oct 2023
Did you know there are scholarship opportunities for #NCMDub24? And we've made it easier! Learn more and join us in Dubrovnik! ncm-society.org/scholarships…
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Thrilled to present our recent paper, just published in @NatureComms. In this work, we unveil a novel facet of #presynaptic_inhibition in the realm of #movement_control. (1/n) 🔗Full paper available here: doi.org/10.1038/s41467-023-4…
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Finally, this remarkable achievement would not have been possible without the tireless dedication of our coauthors, Saeka Tomatsu, Geehee Kim, and Shinji Kubota. (8/n)
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Stay tuned for more exciting reports on the neural mechanisms of sensorimotor control in limb movement from @SekiLabs. (9/n)
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