@SciencesNetwork

Posting research for human genetics, model organism genetics, psychiatry, psychology, neurology, longevity, epidemiology, and more. Please support us:

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Joined April 2023
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Cholecystokinin released somatodendritically from dopamine neurons broadly alters synaptic strength across the ventral tegmental area biorxiv.org/content/10.64898…
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Ex vivo astrocyte-to-oligodendrocyte conversion in human adult cortical tissue using transcription factor overexpression biorxiv.org/content/10.64898…
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Capturing Spatially Organized Oscillatory Cliques as Signatures of Neuronal Assemblies biorxiv.org/content/10.64898…
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Differential Neurodevelopmental Disruption by Bisphenol A (BPA) and Valproic Acid (VPA) in Human Forebrain Organoids biorxiv.org/content/10.64898…
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KMT2C and KMT2D amplify GRHL2-driven enhancer activation biorxiv.org/content/10.64898…
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Sex- and hepatocyte PPARγ-dependent effects of an obesogenic dietary approach to induce MASH with fibrosis in mice biorxiv.org/content/10.64898…
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Clonal memory of cell division in humans diverges between healthy haematopoiesis and acute myeloid leukaemia biorxiv.org/content/10.1101/…

Clonal memory of cell division in humans diverges between healthy haematopoiesis and acute myeloid...

Clonal memory, a cellular property inherited across at least two divisions, has emerged as a key driver of cell heterogeneity. To uncover its roles in human haematopoiesis, we developed high-resolu...

biorxiv.org
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Joint likelihood-free inference of the number of selected single nucleotide polymorphisms and the selection coefficient in an evolving population biorxiv.org/content/10.1101/…
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#GWAS: pubmed.ncbi.nlm.nih.gov/4182… pubmed.ncbi.nlm.nih.gov/4180… pubmed.ncbi.nlm.nih.gov/4153… pubmed.ncbi.nlm.nih.gov/4142… pubmed.ncbi.nlm.nih.gov/4142… pubmed.ncbi.nlm.nih.gov/4136… pubmed.ncbi.nlm.nih.gov/4094…

Simultaneous rapid structure identification and accurate quantitation of chiral drugs based on a...

A chiral drug with different enantiomers exhibits different pharmacological activities. Structure identification, quality control, and accurate quantitation are all important issues for chiral drugs....

pubmed.ncbi.nlm.nih.gov
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Tauroursodeoxycholic acid alleviates depression-like behavior induced by chronic unpredictable mild stress through amelioration of catecholamine imbalance. pubmed.ncbi.nlm.nih.gov/4162…

Tauroursodeoxycholic acid alleviates depression-like behavior induced by chronic unpredictable mild...

Depression is thought to emerge as a result of monoamine neuromodulators' deficiency in a specific central nervous system site. Tauroursodeoxycholic acid (TUDCA) has been found to have a protective...

pubmed.ncbi.nlm.nih.gov
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SV40 exploits the Nesprin-2-SUN1-KPNA4 axis for stepwise targeting and entry into the host nucleus to promote infection biorxiv.org/content/10.64898…
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Mapping the chaperonin TRiC/CCT interactome in mouse photoreceptors reveals functional significance for energy metabolism biorxiv.org/content/10.64898…
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Identification of disease-specific alleles and gene duplications from 1,600 Haemophilus influenzae genomes using predicted protein analyses from an unsupervised language model and clinical metadata biorxiv.org/content/10.64898…
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ESPeR-seq: Extremely Sensitive and Pure, End-to-end, RNA-seq library preparation biorxiv.org/content/10.64898…
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Correction of a recurrent pathogenic variant in methylmalonic acidemia using adenine base editing biorxiv.org/content/10.64898…
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Transcriptional regulation of the TASK-1 potassium channel by ETV1 -Implications for atrial excitability biorxiv.org/content/10.64898…
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microRNAs bidirectionally regulate FUT1 to modulate α-1,2-fucosylation and cancer-associated biology biorxiv.org/content/10.64898…
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Damaged glomeruli in proliferative pediatric lupus nephritis exhibit a C5a-C5aR1 induced fibrotic transcriptional program biorxiv.org/content/10.64898…
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Resistance to Pyrethroids in Aedes aegypti: Insights into Transcriptomic Response to Different Insecticide Concentrations Transcriptomic responses of Aedes aegypti to insecticide concentrations biorxiv.org/content/10.64898…
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In vivo-compatible spatial multi-omics via hydrogen peroxide-independent APEX2 labeling biorxiv.org/content/10.64898…
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