@SaricLab
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Prof of Bio & Soft Matter Physics. Living @ISTAustria; Associated @UCL Physics & @LMCB_UCL. Simulations not animations.
Vienna, Austria
Joined September 2019
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Relaxing #beachread 🏝️: filaments that grow and shrink by burning energy🔥, death💀, assembly, division ring formation 💍, and more in our new paper in @NaturePhysics nature.com/articles/s41567-0…. Great collab with @nartimsoole & @seamus_holden , led by soon-doctor @vainhilla96. ⤵️
Did you know cell filaments love to treadmill? 🔄 They grow and shrink on opposite ends and burn energy doing it! But why? How does it drive self-organisation and bacterial division? Dive into our new publication ft. @SaricLab @nartimsoole @seamus_holden labs to find out! 🧫🔬🖥️
Andela Saric retweeted
Registration is open for the 2025 iteration of the wonderful @EMBOevents workshop on cell polarity and membrane dynamics #EMBOcellPolarity25 I am organizing with Ed Munro! Wonderful lineup wonderful please sign up and RT meetings.embo.org/event/25-c…
Andela Saric retweeted
Are you a fan of #ComputationalBiophysics?🖥️
The @SaricLab at the #ISTA is seeking a talented #PhDcandidate to investigate the fascinating interplay between #MolecularCondensates and #CellMembranes.
Check our #PhDposition: comeincell.org/dc12-in-silic… #MSCA #ComeInCell
Andela Saric retweeted
New edition of Interdisciplinary challenges (IntCha25) on physics of complexity and life will take place at Heidelberg in 2025 embl.org/about/info/course-a… @embl So proud the event keeps gathering ECR for rich exchanges
@Dmichiel1 ready for the 10th anniversaire?
Previous Editions👇
Thank you @AllenInstitute for seeing the magic in #membranebiophysics 🪄✨ We’re thrilled happy to be a part of this cohort!
Using simulations, synthetic cells, and live archaeal cell communities, @SaricLab, @KGoepfrich, and Buzz Baum are challenging the assumption that the cell membrane is passive and only changes shape when acted upon.
#FrontierScience
Andela Saric retweeted
Congratulations to Anđela Šarić @SaricLab on being named an Allen Distinguished Investigator by @PGAFamilyFdn! She will lead an international collaboration, funded with $1.5 million, to investigate how chemically active membranes influence cell shape.
🔗 bit.ly/3B65vJc
ALT ISTA Professor Anđela Šarić © ISTA
Andela Saric retweeted
🤩 Exciting milestone for the #MSCA Doctoral Network #ComeInCell! Today we held our kickoff meeting to drive this groundbreaking project forward.
Stay tuned for insights into #SyntheticBiology, #MembraneCondensates, #NeurodegenerativeDiseases, #MembraneTrafficking & more! 🔬✨
Andela Saric retweeted
📢 Open PhD position as part of #MSCA network of 17 students
@ComeInCell
Interested in exploring membrane stability/repair & #condensates ?
Check out & apply:
👉bit.ly/4fd8HRU
The project will include secondments at
@SaricLab, @MarquesLab & @NatureComms
ALT https://doi.org/10.1038/s41586-023-06726-w
Andela Saric retweeted
We're hiring for a MSCA PhD position! @ComeInCell
We're curious about how biological condensates can be actively targeted to membrane surfaces with the thoroughly mastered self-assembling protein machinery.
Check out the project at comeincell.org/dc03-active-s…
Andela Saric retweeted
The ITN ComeInCell 🧫comeincell.org is UP sand running!
Interested in synthesizing life-like systems from the bottom up?
🔊Apply now to the 2 PhD positions that we offer @ciqus within an outstanding network!!
RT is highly appreciated!
⏰👉 usc.es/ciqus/es/formacion-y-…
Andela Saric retweeted
We're super excited to launch ComeInCell- a doctoral network aimed to develop advanced cellular mimics that integrate functional membrane structures and biomolecular condensates. With a team of 14 PIs and 13 associated partners, this will be an exciting journey!
Andela Saric retweeted
Archeal monolayer membrane properties. Interesting work from @SaricLab.
Are there implications for origin of life?
biorxiv.org/content/10.1101/…
Andela Saric retweeted
Taken together, we find membrane tradeoff design principles evolved in extremophiles - stability vs reshapeability - that can be valuable for (bio)technological applications. (7/7)
🙏 @sciFelixFrey , @xiuyun_jiang , @BaumBuzz @SaricLab
preprint → doi.org/10.1101/2024.10.18.6…
Andela Saric retweeted
Did you know there are more than bilayer #membranes in nature? Meet the #archaeal monolayer and its surprising mechanical properties! New #preprint! (1/7)
A great 🇬🇧-🇦🇹team of @BillieMeadowcr1 (currently cycling 🚴♀️ across 🇺🇸) @IvnPla @v_sorichetti and Eryk teamed up with with @NargessKGharibi and @YanlanMao to simulate collagen-iv remodelling under strain and enzymatic activity. @ISTAustria
@LMCB_UCL @UCL_IPLS More ⬇️
Collagen-IV networks rule the #mechanics of our epithelia, but we know little about how they reshape. Our new preprint (with the 1st coarse-grained MD models of #collagen-IV!) shows how consuming energy during remodelling might make the difference: 📑tiny.cc/s6fqzz 🧵
Apply! 📝
Take your career to the next level: #FacultyCall @ISTAustria is open! We're seeking exceptional group leaders in #chemistry, #ComputerScience, #DataScience, #EarthScience, #LifeSciences, #mathematics, and #SoftMatterPhysics to join our institute.
Apply 🔗 bit.ly/47mxEre
ALT 📸 © Josef Herfert | ISTA
New PhD in the family!: Chris Vanhille Campos @vainhilla96 🍸🥂🧉🧁. Chris was our stellar ☄️💫 student with many passions — from bacterial division, to vesicle reshaping, condensates, self-assembly, guitar, icey Danube 🧊, braving bears, to making softies @ISTAustria happy 🍧
He’s currently travelling around South Korea 🇰🇷🍜 before continuing his research path. ⛰️Huge thanks to Karsten Kruse and Philip Pearce @pearce_maths for being on his committee @UCL_IPLS , and looking forward to all the great things he’ll do in the future.
Andela Saric retweeted
The actin #cortex is attached to the #membrane via linking proteins. When these linkers get trapped in the cortex meshes, actin jams🚧, #contractility stops🛑 and cells polarise☄️Exciting collaboration (+ real fun!) with @diz_lab @TesoroRuben @SaricLab
📑biorxiv.org/content/10.1101/…
New Preprint! How can cells polarize in the absence of a stimulus? We suggest a surprising biophysical mechanism, protein caging!
We reveal how the complex mechanical interactions at the cell surface lead to symmetry breaking.
biorxiv.org/content/10.1101/…
Andela Saric retweeted
New Preprint! How can cells polarize in the absence of a stimulus? We suggest a surprising biophysical mechanism, protein caging!
We reveal how the complex mechanical interactions at the cell surface lead to symmetry breaking.
biorxiv.org/content/10.1101/…