Post-Doc position in the MIMOL departement - Geneva University 🏔🔬 Studying misbehaving microorganism 🦠👨🔬
Joined September 2022
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If you wanna know how important is the apicoplast for toxoplasma bradyzoites check out our work now available on biorxiv 🔬🦠😁!
Is the apicoplast essential for Toxoplasma persistence? Sometimes you have to go through rather convoluted ways to answer a simple question. Huge effort of PhD student @SanchezSyrian in collaboration with the lab of Nico Blanchard @InfinityTLS to find out:
biorxiv.org/content/10.1101/…
Sanchez Syrian retweeted
How does Toxoplasma gondii tachyzoites multiply so efficiently?
Our review dives into the molecular choreography of endodyogeny—scaffolds, transcription factors, and cytoskeleton that enable parasite division.
👉 authors.elsevier.com/a/1lcOh…
@be_maanasa @VMudiyam @TrendsParasitol
Sanchez Syrian retweeted
🚨 2-year post-doc position available in my lab. More details below. Please repost!
acrobat.adobe.com/id/urn:aai…
Sanchez Syrian retweeted
I finally found the time to write a short piece on ATG8ylation of the apicoplast. You may want to check it out here: tandfonline.com/doi/full/10.…
#autophagy #ATG8ylation #apicoplast
Sanchez Syrian retweeted
🚨New paper out! 🚨
The apicoplast is an essential plastid retaining many crucial metabolic pathways 🦠🏭 However, bypassing all of them makes the apicoplast dispensable!
nature.com/articles/s41467-0…
Sanchez Syrian retweeted
Thrilled that @MBoCjournal chose our picture for their March issue cover, always happy when Toxoplasma gets the spotlight! Thanks to the Editors and check out our paper on methylglyoxal metabolism in the apicoplast here: molbiolcell.org/doi/full/10.…
Sanchez Syrian retweeted
Stoked to see the latest research from our lab now out in @PLOSBiology! Check it out to learn more about lineage-specific adaptations in the cytosolic iron-sulfur assembly pathway in Apicomplexa. #ironsulfur #apicomplexa
journals.plos.org/plosbiolog…
Excited to see our paper published in MBOC! 🎉 Our research explores a glyoxalase-like protein in the apicoplast, crucial for Toxoplasma growth and organelle homeostasis maintenance. Huge thanks to the newly promoted Research Director @s_besteiro🏋♂️
doi.org/10.1091/mbc.E24-09-0…
Sanchez Syrian retweeted
Delighted to share our study on a major Toxoplasma virulence factor that prevents lytic host cell death.
Many thanks to @ParaFrap for support, constructive reviews and all labs involved: Melissa Lodoen, Hiba El Hajj, @MGissot, @KarineLeRoch1
Link : rdcu.be/d6m3G
Sanchez Syrian retweeted
You want to know more about iron-sulfur cluster biogenesis in Apicomplexa? Have a look at our latest review, just out in the "Biogenesis and function of FeS proteins" special issue of @BBAjournals BBA Mol Cell Research:
authors.elsevier.com/a/1k7CO…
Sanchez Syrian retweeted
Extremely proud to see this beautiful collaboration with @yiweichang lab published. Thanks to all the people involved in this work. #ExM #CryoET
pnas.org/doi/10.1073/pnas.24…
Sanchez Syrian retweeted
📢Our team is seeking 2 postdocs to join a @ERC_Research funded project on cell cycle regulation of #malaria parasites!
#ParasitologyJobs #Academicjobs #Postdocposition
Deadline: 1/11; Start date: 1/1/2025 (Flexible)
Details here👇
lphi.umontpellier.fr/researc…
Sanchez Syrian retweeted
Years of hard work but is it now officially online. Thank you to my amazing students and collaborators for this great story! A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria | Science science.org/doi/10.1126/scie…
Sanchez Syrian retweeted
#Apicomplexans need specialized structures to invade host cells & replicate. @petersmback @GEWard14 @ToxInLA &co show that alveolin protein IMC6 is crucial for maintaining cellular morphology, invasion & successful replication in #Toxoplasma #PLOSBiology plos.io/3BgjxaE
Sanchez Syrian retweeted
A new study in @PLOSBiology from our lab shows the role of the PP1 phosphatase in controlling the tachyzoite cell cycle and amylopectin storage in T. gondii. Kudos to the two PhD students involved: AS Khelifa and @be_maanasa !
#PLOSBiology: dx.plos.org/10.1371/journal.…
Sanchez Syrian retweeted
Postdoc position available to work with me, in collaboration with Chris Lane @LaneLabURI, on Nephromyces, the closest non-parasitic, extracellular symbiont relatives of the blood parasites (Plasmodium et al). How did the business of blood parasitism start?
jobs.cam.ac.uk/job/48203/
Sanchez Syrian retweeted
Congrats to @SanchezSyrian and all the authors involved in the paper describing a novel protein involved in apicoplast homeostasis and parasite growth! 👏🦠🐈⬛
biorxiv.org/content/10.1101/…
Sanchez Syrian retweeted
New preprint from the lab, as @SanchezSyrian apparently had some time for a little side project towards the end of his PhD. 😉 biorxiv.org/content/10.1101/…
Sanchez Syrian retweeted
Excited to share a new preprint investigating the importance of the mitochondrial transporter ABCB7 for iron-sulfur cluster biogenesis in Toxoplasma. Great collaboration with @s_besteiro
biorxiv.org/content/10.1101/…
Sanchez Syrian retweeted
Ha! Rejoice with me - our paper got published! We developed a method to expand Toxoplasma cysts using ultrastructure expansion microscopy, so now you can do affordable super-resolution protein localisation on the chronic stage too!
tinyurl.com/5xzf524u