Organic chemistry lab at the University of Colorado.
Joined April 2019
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Oh, to be a 55 year old professor again. Do the ducks miss me? I think not. Sadly, I think not...
CU is still scheduled for an in person start to the semester on Jan 9 in just under 2 weeks. Let’s see how thing look after the New Year’s eve celebrations. Hopefully, everyone stays home, drinks a warm glass of milk and gets to bed early, which is the best start to the new year!
A dose of reality to go along with the approval of Merck’s molnupiravir. It's hard to understand how a drug with this exclusive MOA and low efficacy was approved on such a dangerous virus. @michaelzlin is spot on with this opinion piece. washingtonpost.com/outlook/2…
For a related thread by Lin: xitter.cf/michaelzlin/status/147…
Would you prefer (1) we get back to normal activities sometime, or (2) we make new vaccine-evading coronaviruses continuously, suffer widespread breakthrough waves, and wear masks forever?
If you chose #1, then know this: Merck's molnupiravir should not be approved.
Also, difference in dose is very large. Pfizer vaccine dosage: 30 mcg mRNA x 3 shots = 90 mcg. Paxlovid: 600 mg/day x 5 days = 3 g. That's 33,333 x greater by weight which compounds the problem. As Lowe points out, making small molecules lipids for mRNA vaccine was bottleneck.
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Reminds me of pretty much every synthesis or research project we've designed. It's that extra push here and there that makes it work.
Sammakia Lab retweeted
This story in @nytimes, beginning with its headline, fails spectacularly to explain what is happening right now to universities all across this country. The conflicts over plans for the fall are warning signs of an epic crisis for higher ed.
nytimes.com/2020/07/03/us/co…
Professor Slayton A. Evans Jr. was the first African American chemist to be hired at the University of North Carolina Chapel Hill @uncchemistry in 1974. I had him for Organic Chemistry 1 and 2, and for one of the hardest classes I ever took, "Intermediate Organic Chemistry". /1
The second picture in the first tweet in this thread was taken during graduation in 1983. It shows the pupil, awkward, nervous, unsteady, and guided by his advisor's confidence and steady hand. Slayton passed away in 2001 at the age of 57, one year younger than I am today.
In addition to the loss of his mentorship, the world lost a tremendous scientist, thoughtful and detailed in his approach and intellect, and one with much left to contribute.
A belated happy Junteenth, Slayton. #BLM /end