Senior Research Scientist-Clinical Trial Lead Scientist for Off-the-Shelf CAR T cells. UCL GOS ICH.
London, England
Joined August 2017
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- Following570
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Sameer (Farhatullah Syed) retweeted
Just published @NEJM
A striking 90% reduction in death for booster shots (vs not receiving the 3rd shot) among over 840,000 people, age 50 or older
nejm.org/doi/full/10.1056/NE…
Sameer (Farhatullah Syed) retweeted
🗞️@CRISPRTX announced that the FDA granted Regenerative Medicine Advanced Therapy designation to CTX110™, its wholly-owned allogeneic CAR-T cell therapy targeting CD19+ B-cell malignancies.
bit.ly/3cPOoeX
Sameer (Farhatullah Syed) retweeted
“Mask-wearing is the single most effective public health measure at tackling Covid, reducing incidence by 53%, the first global study of its kind shows.”
theguardian.com/world/2021/n…
Sameer (Farhatullah Syed) retweeted
⚠️ COLIN NEEDS OUR HELP! He is just 18 and has blood cancer. His only chance of survival is a blood stem cell donation, but there is no matching donor anywhere in the world. Please RT & help us find Colin his lifesaver 🙏🏽
Request a swab kit to register at bit.ly/3c8dghD
Sameer (Farhatullah Syed) retweeted
#مستشفى_الملك_فيصل_التخصصي ومركز الأبحاث يفوز بجائزة الحسين للتفوّق المؤسسي في مجال الأبحاث لعام 2021
Sameer (Farhatullah Syed) retweeted
Fully vaccinated people account for just 1.2% of COVID deaths in England.
If you retweet one thing today, let this be it.
Please please get vaccinated.
Love,
NHS staff everywhere 💙
PS no hate please, we are literally trying to save your life.
Saudi Arabia’s public investment fund to invest in a city without cars.
m.economictimes.com/news/int…
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Brexit: The EU and UK have reached a post-Brexit trade deal, ending months of disagreements over fishing rights and future business rules bbc.com/news/uk-politics-554…
Covid: New variant found ‘due to hard work of UK scientists’ bbc.com/news/health-55413666
Terminally ill cancer patient has been given the all-clear after becoming the first woman in Wales, to be given CAR-T treatment to fight cancer. bbc.com/news/uk-wales-553200…
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Very nice explanation of
How the Pfizer-BioNTech mRNA Vaccine Works?
Definitely worth a read for those wanting to understand better, and a share for those who'd like to educate their friends, family and colleagues better!
nytimes.com/interactive/2020…
"90-year-old woman in the UK becomes first person to receive the Pfizer COVID-19 vaccine outside clinical trial" xitter.cf/i/events/1336208790622…
Saudi Arabia feels the chill as cool weather sweeps over regions arabnews.com/node/1772626#.X… – at Jeddah, Kingdom of Saudi Arabia
Gene Editing Shows Promise in Sickle-Cell Disease. Drug development for sickle-cell disease, largely overlooked for decades. Data published in the New England Journal of Medicine report promising results from studies of experimental therapies (1/2).
nejm.org/doi/full/10.1056/NE… – at Jeddah, Kingdom of Saudi Arabia
Numerous ways for gene editing for precision medicine, such as use of viral vectors. However, use of viral vectors has some serious concerns.
Lipid nanoparticles are clinically approved non-viral nucleic acid delivery systems.
advances.sciencemag.org/cont… – at Camden Town, London
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Best example is mRNA1273 LNP-encapsulated mRNA-based vaccine forCOVID19. Furthermore recently shown that light-sensitive LNP delivery offers precise gene editing with CRISPR-Cas9.Disruption of gene expression in-vivo using non-viral approaches opens new avenues for gene editing. – at Camden Town, London
The FDA has granted fast track designation to “Off-the-Shelf” CAR T-Cell Therapy for relapsed or refractory multiple myeloma. globenewswire.com/news-relea… – at Enfield, London
This is our 3 years of hard work to produce Ultra-pure Off-The-Shelf CAR T Cells for CD19. So happy to see finally bench to clinic. This is just the beginning, I am more excited for the upcoming Off-The-Shelf CAR T cells for AML (CARAML) using Base Editing.crisprmedicinenews.com/news/… – at Camden Town, London
CAR T cells display potent antitumor immunity, but T cell exhaustion can compromise their efficacy.Zhi et al., showed that using helper and killer T cells modified to express a constantly active form of STAT5 led to tumor regression in cancer mouse models. immunology.sciencemag.org/co… – at Tottenham, London