Research Fellow at the University of Oxford; CRISPR Screens and functional genomics for Alzheimer’s Disease 🧬 Part time jazz-man/baker/climber. Views my own.
Oxford
Joined December 2012
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Dr Sam Washer retweeted
I am thrilled to announce that my first, first-author publication from my PhD journey is now finally live on bioRxiv! biorxiv.org/content/10.1101/… 🥳🍾👏🎉
In this work, we used iPS-microglia to create a ‘’Everything you ever wanted to know about human microglial reaction to tau…’’
Dr Sam Washer retweeted
We're back in the studio today, recording a podcast with @nottalexi @Josiaharvey @sj_marzi @SamWasher2 & hosted by @FHMcLean.
Can you guess the topic?
Dr Sam Washer retweeted
If you are at #ADPD2024 in Lisbon come see our posters of our studies of DNA methylation meta-analyses in Lewy body disease led by @Josiaharvey and @Jenny_Imm, and spatial transcriptomics in the J20 amyloid model led by @millie_sander – at Almada, Portugal
Dr Sam Washer retweeted
Excited to see this work from my Postdoc in Andrew Bassett's lab at @sangerinstitute finally out in the world! biorxiv.org/content/10.1101/… we found an AD-associated variant in PTK2B that actually has a causal effect on chromatin accessibility, gene expression and microglial function
Dr Sam Washer retweeted
Microglia NLRP3 inflammasome 'DUBbed' by UCH-L1 @Zhu_L_Oxford @AndreasDamiano2 @flassen_ @ProteomOX @TaoDongGroup @theRafLab @TateScience @CmdOxford @CAMS_COI_Ox @ARUK_ODDI @KirOxford @bdi_oxford @HumanGeneticsOx @Dunn_School @NDMOxford biorxiv.org/content/10.1101/…
Dr Sam Washer retweeted
Come hear @MartaP4lcantara presenting on how we're mapping sceQTLs in iPSC-derived microglia to interpret neurodegeneration GWAS variants. Starting soon: 11:45am Ballroom A. A collaboration with @OpenTargets #ASHG2023
Dr Sam Washer retweeted
1 in 3 names are missing on the #Lionesses shirts tonight, representing the 1 in 3 of us born in the UK today who will develop dementia.
Tonight’s match was dedicated to @alzheimerssoc, raising vital funds to those devastated by dementia.
Donate now: alzheimers.org.uk 👈
Dr Sam Washer retweeted
#DataScience #PhD opportunity for quantitative student looking to apply their skills to big biological datasets. Be part of the @GW4BioMedDTP @ExeterMed and @PsyEpigenetics exploring methods to computationally derive cell-type specific epigenetic profiles to understand
Dr Sam Washer retweeted
Position available at @ExeterMed to work with on alternative splicing and epigenetic modifications in models of Alzheimer's disease pathology. @ExeterNeuro jobs.exeter.ac.uk/hrpr_webre… Please RT!
Dr Sam Washer retweeted
We’re hiring! Please reach out or RT if you might know of someone intersted:
- Computational biologist (esp. AI & ’omics) bit.ly/3n4tE84
- RA in cell culture (esp. iPSC) bit.ly/3O3qdKN
- RA in mol bio (esp. cloning & CRISPR) bit.ly/3xCIsQj
#sciencejobs
Dr Sam Washer retweeted
"Working class people should aim lower than Oxbridge."
We assume "lower" is in relation to height above sea level, and so have produced The University Elevation Rankings.
➡️ bantshire.github.io/ranking-…
Dr Sam Washer retweeted
Come and join our great team and live in an amazing part of the world. Post-doc bioinformatician post working on cancer and metabolic traits. Pls RT @awebster90 @timfrayling @PsyEpigenetics @ExeterMed
jobs.exeter.ac.uk/hrpr_webre…
Dr Sam Washer retweeted
This picture taken @SCICambridge is of microglia cells.
These important cells carefully clear up protein waste in the brain allowing them to function. Scientists are studying these cells to understand how targeted treatments can support them - to help people with dementia.
Dr Sam Washer retweeted
What do we know so far about the #COVID19 Danish ‘Cluster 5’? Check out the latest explainer from COG-UK, on the the mutations and science behind the current #SARSCoV2 mink outbreak. bit.ly/32p52x2
Dr Sam Washer retweeted
Work with us in Exeter! Are you interested in a 4-year postdoc focused on advancing disease genomics research using cutting-edge technologies (@illumina @nanopore @PacBio @10xGenomics) in beautiful Devon? Find out more: ow.ly/9fMh50BpXuc Please RT! @ExeterMed @UofE_Research
Dr Sam Washer retweeted
1/3 Latest preprint from the team @PaulWP_ @SamWasher2 @aaron_r_j @ElkyD - In one line - Acute but not recurrent low glucose (RLG) induces genes involved in the unfolded protein response in human primary astrocytes @PsyEpigenetics #ExeterDiabetes – at Broadclyst, England
Analysis of the transcriptome and DNA methylome in response to acute and recurrent low glucose in human primary astrocytes biorxiv.org/cgi/content/shor… #biorxiv_neursci
Dr Sam Washer retweeted
How is our COVID-19 vaccine research progressing? If you've got questions about our potentially life-saving work, join today's #COVIDConversations for a live talk/Q&A with Professor Gilbert - live at 1:30pm: youtu.be/MKNavonhXyk
Dr Sam Washer retweeted
Just published @CellCellPress: From 60 patients convalesced from #COVID19, single-cell sequencing of their B cells-> 14 potent neutralizing monoclonal antibodies. With 1 #3D crystal structure, and model efficacy in hACE2 mice as preventive therapy. Wow.👍
cell.com/cell/fulltext/S0092…
Dr Sam Washer retweeted
GOVERNMENT URGED TO RETHINK ‘DANGEROUS’
COVID-19 STRATEGY OF MANAGING NOT SUPPRESSING VIRUS
Watch #IndependentSAGE press conference with
@Sir_David_King - today, 12 May, at 12pm on Independent SAGE YouTube channel
youtube.com/channel/UCqqwC56…