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New publication from our lab shows how a muscle myosin regulates metabolism featured in Science Advances @ScienceAdvances. science.org/doi/10.1126/scia…
Congratulations @Jaydeep_Sharma_ @somnath_im @aparnarai_27 @MahimaK2104 @AnushreeBharad5 for the dedication, perseverance & hard work
New publication from our lab describes the skeletal muscle defects in Parkinson's Disease using a mouse model. Congratulations to @Jaydeep_Sharma_ @somnath_im @Krishna_SBisht Ankit Biswas & Lakshmikanthan P & @Tushar_RCB
nature.com/articles/s41419-0…
This study is from an excellent collaboration wh @Tushar_RCB lab. Grateful to @unescorcb for funding. The skeletal muscle loss in Parkinson's Disease results from elevated oxidative stress and cellular senescence causing reduced levels of the LaminA/C nuclear membrane protein.
Sam Mathew retweeted
The skeletal muscle slow myosin heavy chain regulates mammalian metabolic homeostasis through the NRF2 pathway
science.org/doi/10.1126/scia…
3. The NRF2 pathway is a crucial therapeutic target to control the type 2 diabetes, metabolic and muscle dysfunction associated with loss of myosin heavy chain-slow. Using a mouse model that we developed, we can rescue these defects by giving sulforaphane, which activates NRF2.
2. How myosin heavy chain-slow regulates fiber type, mitochondrial properties and metabolic function in the mammalian skeletal muscle is studied in this work. Grateful to @DBTIndia and @unescorcb for funding support 🙏
Sam Mathew retweeted
Our commitment to advancing healthcare goes hand in hand with empowering those who drive it forward. Sun Pharma Science Foundation’s Science Scholar Fellowship supports young researchers whose work holds the promise to create lasting impact. Congratulations to the 2025 winners!
Sam Mathew retweeted
A proud moment for RCB!
Congrats to Mr. Jaydeep Sharma from RCB, Faridabad for receiving the Sun Pharma Science Scholar Fellowship in Pharmaceutical Sciences 2025 by the Sun Pharma Science Foundation.
@DBTIndia @UNESCO @ArvindK_Sahu @shivanivashist5
Excited and thrilled that Jaydeep Sharma from our lab @unescorcb has been awarded a Sun Pharma Science Scholar Fellowship in Pharmaceutical Sciences for 2025. Congratulations Jaydeep for this wonderful achievement. sunpharmasciencefoundation.n…
@Jaydeep_Sharma_
Sam Mathew retweeted
We are excited to host our alumnus Dr. Bhargab Kalita on 25 July for a research talk. He will be talking about the therapeutic challenges of high-risk #rhabdomyosarcoma. Dr Kalita did his post-doctoral research in Prof Sam Mathew's lab & is currently working at NYU School of Med.
Sam Mathew retweeted
The Developmental Genetics Laboratory at @unescorcb hosted B.Tech Biotechnology students from MGM College of Agricultural Biotechnology on their educational tour! It was a fantastic experience for our lab members, filled with fun, teaching, and learning.
Sam Mathew retweeted
Join us tomorrow to know more about the i3c BRIC-RCB PhD program in Biosci with Dr Sivaram Mylavarapu.
i3c BRIC-RCB PhD is a collaborative initiative of BRIC with RCB & ICGEB, a new PhD training model based on the principles of ideate, immerse, innovate & collaborate #i3c.
Sam Mathew retweeted
Thanks @CellCellPress for highlighting our exciting scientific discoveries @nyugrossman @nyulangone @mikedyerlab
Now online! PAX translocations remodel mitochondrial metabolism through altered leucine usage in rhabdomyosarcoma dlvr.it/TK0B7D
Sam Mathew retweeted
Participated in and moderated a panel discussion on "Women in Science" at RCB's Annual Scientific Retreat on International Women's Day. We discussed gender stereotypes and biases, and how we can empower women to achieve their full potential. @unescorcb
Sam Mathew retweeted
Attended #YIM2025 at Agra. A meeting that brings together young investigators, postdoctoral fellows, mentors and institutional representatives. One of it's kind and meticulously organized by @IndiaBioscience @unescorcb
Sam Mathew retweeted
The first mentor talk is underway! 🎙️
@deepjxtal (@unescorcb) offers incredible insights into the field and the challenges she has overcome during her research journey.
"It's never too late. Don't self-reject yourself before applying."
@IndiaBiofilms
Sam Mathew retweeted
UNESCO Regional Centre for Biotechnology (RCB) commemorated National Science Day on February 28, 2025, with an Open Day event that drew over 1,500 students from schools and colleges.
Sam Mathew retweeted
40 years since the Heidelberg genetic screen that revolutionized developmental and cell biology
Read this Perspective article from Mark Peifer @peiferlabunc, revisiting the genesis of the Heidelberg screen and the stories behind the experiments:
journals.biologists.com/dev/…
ALT The mutants identified in the X-chromosome screen. Derived with permission from Wieschaus et al. (1984).
Sam Mathew retweeted
At @ccmb_csir, we look forward to your participation in a Muscle workshop covering concepts and practices across scales and species on Nov 4th-7th '24. Accomplished speakers and hands on training. PhD students to new PIs, do apply and share. youtu.be/3sTN-RcRles #MyoTwitter
