@S_Ray_09

Postdoc UNC Chapel Hill O'Brien Lab | PhD Augusta University O'Connor Lab | Renal Physiology and Acute Kidney Injury | she/her

 Chapel Hill, NC
Joined October 2018
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Interested in ischemic kidney injury? My recent review in Comprehensive Physiology details the role of red blood cell trapping (vascular congestion) to meditate tubular injury in ischemic AKI. @APSPublications onlinelibrary.wiley.com/doi/…
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Sarah Ray retweeted
Duke Kidney@DukeKidneyFeb 13
Sarah McLarnon, PhD (UNC) Taylor Kress, PhD (Duke) and Brendyn Miller, PhD (Wake Forest) present their research at Duke Nephrology Grand Rounds as trainees part of the NC TRIO NIH U2C/TL1 training grant
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Sharing this excellent review now out from postdoc Sarah McLarnon! Lots of useful info on 3D imaging, quantification of imaging data, and how this has been applied to the kidney. #FluorescenceFriday figure with our own imaging data! sciencedirect.com/science/ar…
Figure from our review paper showing various fluorescence microscopy images of cells and structures of the kidney

ALT Figure from our review paper showing various fluorescence microscopy images of cells and structures of the kidney

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Intermediate mesoderm isn't the sole contributor to nephrons in zebrafish-new manuscript out showing somites are a source of nephron progenitors! Led by Alan Davidson's group. Many fun discussions were had-grateful for the inclusion! nature.com/articles/s41467-0…
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For #FluorescenceFriday sharing the fantastic work of postdoc Sarah McLarnon! A follow up to our '23 Development paper where we asked: Does precise vascular patterning matter for function and what happens after ischemic injury? The results were surprising! journals.physiology.org/doi/…
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So excited to see @P_NGUETTA manuscript officially published! 🎉 He has put in an enormous amount of work to detail kidney innervation @l_obrien_lab Comprehensive mapping of sensory and sympathetic innervation of the developing kidney: Cell Reports cell.com/cell-reports/fullte…

Comprehensive mapping of sensory and sympathetic innervation of the developing kidney

N’Guetta et al. map the spatiotemporal innervation of the developing mouse kidney. They find that innervation begins at E13.5 and that this network expands with the arterial tree. Sympathetic and...

cell.com
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Editorial on our recent work in function academic.oup.com/function/ad…

Function

journals.physiology.org
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Congrats to newly minted PhD Matt Stevenson! A stellar defense and so well deserved. He was the first grad student to join my lab. It was an honor to be his mentor and I look forward to all the amazing accomplishments yet to come in his postdoc and beyond!
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View of today's eclipse from NC @UNC @l_obrien_lab
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Another great @APSPhysiology Summit! So great to catch up with everyone @AUG_University #APS2024
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Thank you @WEHsectionAPS for inviting me to share our work at Data Diuresis!
Annet Kirabo D.V.M., M.Sc., Ph.D., F.A.H.A.@annetkiraboc15 Apr 2024
Congratulations Data Diuresis winner! Fantastic talk on “Piezo2 in kidney development and physiology” by Sarah McLamon, PhD ⁦@APSPhysiology⁩ #APS2024!
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Stop by the WEH and Renal poster sessions to learn more about renal innervation from our lab! Poster boards 812, 865, & 263 @P_NGUETTA @l_obrien_lab
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Thanks @APSPhysiology for great poster sessions @l_obrien_lab @P_NGUETTA
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Congrats to @P_NGUETTA from @l_obrien_lab for receiving the renal recognition award at his first #APS2024 @APSPhysiology
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Fantastic talk from @desmondmoronge on pregnancy after AKI in the Advanced in Renal Physiology session! @APSPhysiology
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For this #FluorescenceFriday, an image showing innervation of the postnatal (P0) kidneys and bladder. Courtesy of postdoc @S_Ray_09 and grad student @P_NGUETTA.
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This review also highlights the hypotheses surrounding the development of RBC trapping as well as summarizes the newest data from the @PaulMOConnor1 lab regarding it's initiation
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Our most recent paper investigating the mechanisms of RBC trapping on ischemic injury from the O'Connor lab is out now in the newest issue of Function! @PaulMOConnor1
Function@APS_Function18 Sep 2023
#AdvanceArticle: "Extravasation of Blood And Blood Toxicity Drives Tubular Injury from RBC Trapping in Ischemic AKI" by McLarnon et al. ow.ly/Y1yT50PLoUp #renal
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#AdvanceArticle: "Extravasation of Blood And Blood Toxicity Drives Tubular Injury from RBC Trapping in Ischemic AKI" by McLarnon et al. ow.ly/Y1yT50PLoUp #renal
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Our new paper investigating mechanisms of RBC trapping in ischemic AKI! @APS_Function
Paul O’Connor@PaulMOConnor17 Sep 2023
The textbooks suggest kidney injury in ischemic AKI is due to medullary hypoxia. Our new paper challenges this hypothesis. Our data suggest injury is secondary to RBC tapping and toxic injury from the extravasation of blood. academic.oup.com/function/ad…

Function

journals.physiology.org
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