@SLoopmans

Metabolomics enthusiast | Metabolomics Core Facility, CCB, VIB | Laboratory of Applied Mass Spectrometry, KU Leuven

Joined February 2020
  • Tweets140
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  • Followers219
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nature.com/articles/s42255-0… (4/4)

The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in...

Nature Metabolism - Loopmans et al. show that the pentose phosphate pathway in chondrocytes provides reducing power to ensure proteostasis necessary for bone lengthening.

nature.com
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As usual, teamwork makes the dreamwork and this would have not been possible without the help of @SteveStegen, @katerinarohlena, @CarmelietLab, @LambrechtsDLab and many others, as well as @FWOVlaanderen and @KU_Leuven for the funding!! (3/4)
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We found that loss of G6PDH does not affect chondrocyte proliferation, but reduces NADPH, especially during differentiation: NADPH provides reducing power to safeguard oxidative protein folding, sustains proteostasis and protects against ferroptosis (2/4)
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Very happy to share the final chapter of my PhD Research with @GeertLab, now online in @NatMetabolism, revealing that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival to ensure chondrocyte functioning and bone lengthening (1/4)
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Time-lapse of our latest asset: meet the Echo-zenoTOF (@SCIEXnews). We will move into large cohort screening with analysis time as low as 0.3 sec/sample. The Echo is currently on its way to Hamilton (@HamiltonCompany) for robotics integration @FWOVlaanderen @VIBLifeSciences
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Shauni Loopmans retweeted
Steve Stegen@SteveStegen24 May 2024
First conference, first presentation! Stellar performance by Lore Rosseels, discussing the role of the glycolytic regulator PFKFB3 during #bone development and #metabolism! #proudPI #ects2024
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Shauni Loopmans retweeted
CCB_VIB_KUL@vib_ccb14 May 2024
Last weekend, a CCB delegation cycled the #1000km of @komop_tgkanker 🚴🚴 Together with 1250 other teams, they managed to collect almost 7M EUR to support cancer research! Amazing effort, amazing team 🤩 Thank you Bram, Shauni, Isabelle, Lars, Alexandra, Frederik en Amelie!
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Last week 2 of our colleagues (Shauni and Lars) cycled to raise money for the cancer research foundation @komop_tgkanker. Together with other cyclists they raised close to 7M euro!! @VIBLifeSciences @KU_Leuven @vib_ccb – at Geetbets, België
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About last week's site visit @thermosci in Bremen: #technology #breakingboundaries #OrbiTRAP #singlecell. Thank you @thermosci for the hospitality and interesting discussions! Looking forward to a new era of -omics @asso_kuleuven @vib_ccb @CBD_VIB
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And most importantly, grateful for the amazing team I have, every step, they supported, no matter how crazy the challenge or requests I had, they joined in the endeavour. Never had so much fun in all the steps of this grant application. We are LAMaS!!Thanks!!!
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Shauni Loopmans retweeted
Steve Stegen@SteveStegen13 Mar 2024
📢 PhD position available in our #research group 📢 We have an exciting project for a motivated #PhD student to study the impact of gender-affirming therapy on #bone! More info 👇: kuleuven.be/personeel/jobsit… Please share and RT! @KU_Leuven @ECTS_science @AcademyEcts @ASBMR
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Congratulations @protonsponge87 (aka Marco Giampa) for obtaining a MSCA postdoctoral fellowship! Thank you so much @MSCActions and @EU_Commission for supporting a talented young researcher keen on developing new metabolomics technologies! @KU_Leuven @VIBLifeSciences @vib_ccb
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Shauni Loopmans retweeted
Steve Stegen@SteveStegen10 Jan 2024
Very happy to share our latest work @GeertLab on the role of de novo #serine synthesis for #osteoclast differentiation, now online @NatMetabolism! 🥳nature.com/articles/s42255-0…

The serine synthesis pathway drives osteoclast differentiation through epigenetic regulation of...

Nature Metabolism - Stegen et al. show that serine metabolism is transiently upregulated during osteoclastogenesis, and it drives osteoclast differentiation via epigenetic regulation of NFATc1...

nature.com
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Do you want to know more about cancer metabolism? @VIBMetaboCoreLV is ready to teach you. Join us : KU Leuven - Wat eten kankercellen? - Op Locatie - dagvandewetenschap.be/activi…. And here is a sneak preview on how food is used to support growth of cells. @VIBLifeSciences @KU_Leuven
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Replying to @SCEBP_Lab @VIBMetaboCoreLV @VIBLifeSciences @vib_ccb
Thank you Christa!!
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Wait for ittttttt.... Very excited to announce the start of a new chapter in my academic career @VIBMetaboCoreLV ! #Metabolomics always had a special place in my heart, so I am ready to take it to the next level!! @VIBLifeSciences @vib_ccb
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Shauni Loopmans retweeted
Steve Stegen@SteveStegen22 Jun 2023
📢 PhD position available 📢 We have an exciting project for a motivated #PhD student to study how #metabolic alterations in skeletal progenitors cause #osteoporosis! More info 👇: kuleuven.be/personeel/jobsit… Please share and RT! #research #bone @ECTS_science @AcademyEcts @ASBMR
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Shauni Loopmans retweeted
Steve Stegen@SteveStegen17 Apr 2023
Awesome work by Karina Geurtzen @GeertLab on the role of #mitochondrial respiration for #bone #metastasis formation! #ECTS2023
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Shauni Loopmans retweeted
Steve Stegen@SteveStegen17 Apr 2023
Great presentation by @KarelDavid_ providing novel #clinical insights on the impact on #bone of targeting #androgen signaling in prostate #cancer patients! #ECTS2023
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Shauni Loopmans retweeted
Karel David@KarelDavid_16 Apr 2023
Early morning start with great talk on skeletal cell metabolism @SteveStegen #ECTS2023
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